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Critical Care General

Risk factors for aspiration pneumonia in patients with dysphagia undergoing videofluoroscopic swallowing studies: A retrospective cohort study.

Nov 16, 2020

Prediction of aspiration pneumonia development in at-risk patients is vital for implementation of appropriate interventions to reduce morbidity and mortality. Unfortunately, studies utilizing a compre...

Influence of microcatheter position on first-pass success of thrombectomy for acute ischemic stroke.

Nov 12, 2020

In acute ischemic stroke, patient outcomes can be improved by first-pass successful recanalization of the occluded vessel. This study investigated whether microcatheter position could influence the su...

Continuous Interrupted Double Throw Suturing Method: A novel suturing technique for Extracranial-Intracranial Bypass.

Nov 12, 2020

Despite failure of "The EC/IC Bypass Study Group" to demonstrate effectiveness in minimizing future stroke events, STA-MCA bypass remains an essential treatment for complex giant intracranial aneurysm...

The long-term impact of perioperative red blood transfusion on patients undergoing cardiac surgery.

Nov 12, 2020

There is a known association between need for transfusion and short-term outcomes in patients undergoing cardiac surgery. However, long-term data are lacking in the contemporary literature.All patient...

Association between red blood cell distribution width and mortality of COVID-19 patients.

Nov 12, 2020

We have previously reported an association between high red blood cell distribution width (RDW) and mortality in septic and brain infarction patients. However, no association between RDW and mortality...

Relevance of Angiotensin-(1-7) and its receptor Mas in pneumonia caused by Influenza virus and post-influenza pneumococcal infection.

Nov 12, 2020

Resolution failure of exacerbated inflammation triggered by Influenza A virus (IAV) prevents return of pulmonary homeostasis and survival, especially when associated with secondary pneumococcal infect...

AI-driven quantification, staging and outcome prediction of COVID-19 pneumonia.

Nov 12, 2020

Coronavirus disease 2019 (COVID-19) emerged in 2019 and disseminated around the world rapidly. Computed tomography (CT) imaging has been proven to be an important tool for screening, disease quantific...

Pathological findings in a patient with alpha-synuclein p.A53T and familial Parkinson's disease.

Nov 12, 2020

The present report documents a patient harboring an alpha-synuclein p.A53T variant from a family presenting with autosomal dominant inheritance, including four patients clinically diagnosed with Parki...

Clinical characteristics of 10 children with a pediatric inflammatory multisystem syndrome associated with COVID-19 in Iran.

Nov 12, 2020

Although symptoms and signs of COVID-19 (Coronavirus disease 2019) in children are milder than adults, there are reports of more severe cases which were defined as pediatric inflammatory multisystem s...

Molecular mechanisms of organ damage in sepsis: an overview.

Nov 12, 2020

Sepsis is one of the most common reasons for hospitalization. This condition is characterized by systemic inflammatory response to infection. International definition of sepsis mainly points out a mul...

Vitamin D and Streptococci: The Interface of Nutrition, Host Immune Response, and Antimicrobial Activity in Response to Infection.

Nov 12, 2020

species are common causes of human infection. These Gram-positive, encapsulated bacterial pathogens infect diverse anatomic spaces, leading to infections including skin and soft tissue infection, end...

Autophagy Activation Represses Pyroptosis through the IL-13 and JAK1/STAT1 Pathways in a Mouse Model of Moderate Traumatic Brain Injury.

Nov 12, 2020

The newly highlighted research into programmed cell death (PCD), autophagy dependent cell death and pyroptotic cell death, has shown that these processes are both strongly correlated with the patholog...

An update on the association between traumatic brain injury and Alzheimer's disease : focus on tau pathology and synaptic dysfunction.

Nov 12, 2020

L.P. Li, J.W. Liang and H.J. Fu. An update on the association between traumatic brain injury and Alzheimer's disease : focus on tau pathology and synaptic dysfunction. NEUROSCI BIOBEHAV REVXXX-XXX,202...

Resting heart rate as an important predictor of mortality & morbidity in ambulatory patients with heart failure: A systematic review & meta-analysis.

Nov 12, 2020

Resting heart rate is a risk factor of adverse heart failure (HF) outcomes; however, studies have shown controversial results. This meta-analysis evaluates the association of resting heart rate with m...

Interrelationship between renin-angiotensin-aldosterone system and oxidative stress in chronic heart failure patients with or without renal impairment.

Nov 12, 2020

We investigated oxidative stress and RAAS biomarkers, as well as their association, in chronic heart failure (CHF) patients on optimized medical therapy, stratified by disease severity or by renal fun...

Heart Failure Results in Inspiratory Muscle Dysfunction Irrespective of Left Ventricular Ejection Fraction.

Nov 12, 2020

Exercise intolerance in heart failure with reduced ejection fraction (HFrEF) or heart failure with preserved ejection fraction (HFpEF) results from both cardiac dysfunction and skeletal muscle weaknes...

A clinic blueprint for post-COVID-19 RECOVERY: Learning from the past, looking to the future.

Nov 12, 2020

The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic poses extraordinary challenges. The tremendous number of coronavirus disease 2019 (COVID-19) cases in the United States has re...

Tranexamic Acid Inhibits Hematoma Expansion in Intracerebral Hemorrhage and Traumatic Brain Injury. Does Blood Pressure Play a Potential Role? A Meta-Analysis from Randmized Controlled Trials.

Nov 12, 2020

Tranexamic acid (TXA) is an antifibrinolytic agent, which has shown an effect on reducing blood loss in many diseases. Many studies focus on the effect of TXA on cerebral hemorrhage, however, whether ...

Characteristics and Comparison of 32 COVID-19 and Non-COVID-19 Ischemic Strokes and Historical Stroke Patients.

Nov 12, 2020

The presence of COVID-19 infection may increase the risk of thrombotic events including ischemic strokes. Whilst a number of recent reports suggest that COVID-19 associated stroke tends to be severe, ...

Neonatal late-onset infection with SARS CoV-2

Nov 09, 2020

During the SARS COV-2 pandemic, the vast majority of infected patients are showing symptoms related to lung damage. At pediatric ages, especially newborns, symptoms from other organ systems without re...

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