Appropriate re-evaluation after neoadjuvant treatment (NAT) is important for optimal treatment selection. Nonetheless, determining the operative eligibility of patients with a modest radiologic response remains controversial. This study aimed to...
Gastroenterology
RELEVANT ARTICLES IN Gastroenterology
Identification of myoferlin as a mitochondria-associated membranes component required for calcium signaling in PDAC cell lines.
Identification of myoferlin as a mitochondria-associated membranes component required for calcium signaling in PDAC cell lines.
Pancreatic ductal adenocarcinoma is an aggressive cancer type with one of the lowest survival rates due to late diagnosis and the absence of effective treatments. A better understanding of PDAC biology will help researchers to discover the Achilles' heel of cancer...
Risdiplam therapy in adults with 5q-SMA: observational study on motor function and treatment satisfaction.
Risdiplam therapy in adults with 5q-SMA: observational study on motor function and treatment satisfaction.
We aimed to describe the experience of a single neuromuscular center in Germany in treating adult spinal muscular atrophy (SMA) patients with risdiplam and to analyze motor function and treatment satisfaction during a follow-up period up to 20Â months.Fourteen...
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Mucosal host-microbe interactions associate with clinical phenotypes in inflammatory bowel disease.
Mucosal host-microbe interactions associate with clinical phenotypes in inflammatory bowel disease.
Disrupted host-microbe interactions at the mucosal level are key to the pathophysiology of IBD. This study aimed to comprehensively examine crosstalk between mucosal gene expression and microbiota in patients with IBD. To study tissue-specific interactions, we...
Fractal analysis of extracellular matrix for observer-independent quantification of intestinal fibrosis in Crohn’s disease.
Fractal analysis of extracellular matrix for observer-independent quantification of intestinal fibrosis in Crohn’s disease.
Prevention of intestinal fibrosis remains an unresolved problem in the treatment of Crohn's disease (CD), as specific antifibrotic therapies are not yet available. Appropriate analysis of fibrosis severity is essential for assessing the therapeutic efficacy of...
Solobacterium moorei promotes the progression of adenomatous polyps by causing inflammation and disrupting the intestinal barrier.
Solobacterium moorei promotes the progression of adenomatous polyps by causing inflammation and disrupting the intestinal barrier.
Adenomatous polyps (APs) with inflammation are risk factors for colorectal cancer. However, the role of inflammation-related gut microbiota in promoting the progression of APs is unknown.Sequencing of the 16S rRNA gene was conducted to identify characteristic...
Anal incontinence after obstetrical anal sphincter injury significantly impacts quality of life for women: a cohort study.
Anal incontinence after obstetrical anal sphincter injury significantly impacts quality of life for women: a cohort study.
To assess the prevalence of anal incontinence (AI) after obstetrical anal sphincter injuries (OASIS) and its severity, as well as the risk factors for AI and AI episodes ≥ 6 months.This prospective and observational monocentric cohort study included all the women...
Prevalence of urinary incontinence and associated factors in nursing homes: a multicentre cross-sectional study.
Prevalence of urinary incontinence and associated factors in nursing homes: a multicentre cross-sectional study.
Urinary incontinence (UI) is a common geriatric syndrome with high health and socio-economic impacts in nursing home (NH) residents.To estimate the prevalence and types of UI and its associated factors in older people living in NHs in Central Catalonia (Spain). We...
Coverage for evidence-based cancer survivorship care services.
Coverage for evidence-based cancer survivorship care services.
The American Society of Clinical Oncology Cancer Survivorship Committee established a task force to determine which survivorship care services were being denied by public and private payers for coverage and reimbursement.A quantitative survey instrument was...
Pregnancy complications and loss: an observational survey comparing anesthesiologists and obstetrician-gynecologists.
Pregnancy complications and loss: an observational survey comparing anesthesiologists and obstetrician-gynecologists.
While there is increasing information regarding the occupational risks to pregnant physicians, there is inconsistent and limited subspecialty data. Physicians may be at increased risk for pregnancy complications due to occupational exposure, long work hours,...
Reproductive autonomy and the experience of later-than-desired pregnancy: results from a cross-sectional survey of reproductive-aged women in Uganda.
Reproductive autonomy and the experience of later-than-desired pregnancy: results from a cross-sectional survey of reproductive-aged women in Uganda.
The focus of reproductive autonomy research has historically been on the experience of unintended pregnancy and use of contraceptive methods. However, this has led to the neglect of a different group of women who suffer from constraints on their reproductive...
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A Doctor’s Three Energy Accounts 2
A Doctor’s Three Energy Accounts 2
by Dike Drummond, MD. When discussing the personal energy of a practicing physician, you must first discard any comparison to a battery. The Energizer Bunny stops when his batteries get to zero. But you never stop. Rather than batteries, we have an internal “energy...
A Doctor’s Three Energy Accounts
A Doctor’s Three Energy Accounts
by Dike Drummond, MD. When discussing the personal energy of a practicing physician, you must first discard any comparison to a battery. The Energizer Bunny stops when his batteries get to zero. But you never stop. Rather than batteries, we have an internal “energy...
CME / CE
CME/CE: Assessing the Associations Between Blood Pressure Variability, Diuretics & Cardiovascular Events in Patients With CKD
CME/CE: Assessing the Associations Between Blood Pressure Variability, Diuretics & Cardiovascular Events in Patients With CKD
This course discusses a study that recognize blood pressure variability (BPV) as a potential modifiable risk factor in the cardiovascular health of patients with CKD.
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Why Physicians Should Not Ignore Medical Board Complaints
Why Physicians Should Not Ignore Medical Board Complaints
While many physicians have the foresight to proactively protect themselves in the event of a medical malpractice suit, they are often less prepared to handle a possible medical board complaint. Not only can a medical board complaint negatively impact a physician’s...
How Social Media Can Be a Positive Force in the Healthcare Industry
How Social Media Can Be a Positive Force in the Healthcare Industry
Another positive aspect of medical social media is its ability to expand the lines of social and intellectual communication among physicians.
Women Physicians Still Face Pay Inequities
Women Physicians Still Face Pay Inequities
Disparities in pay based on gender are, unfortunately, a persistent problem in our country for all sectors, including healthcare. Women physicians have been up against the gender pay gap for decades, yet they continue to rally for equal pay. Cardiologist Yasmine S....
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