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Ophthalmology General

A multicenter clinical trial of orthokeratology in school-aged children and adolescents in Japan.

May 31, 2021

This study investigated the safety and efficacy of orthokeratology in myopic children in Japan.Prospective clinical trial.This study enrolled myopic children aged 6-16 years with a spherical equivale...

Impact of virtual reality headset use on eye blinking and lipid layer thickness.

May 31, 2021

Blinking plays an important role in protecting the eyes, and the use of computers has been associated with a reduction in the blink rate. The goal of this study was to evaluate the effect of a virtual...

Combined Intense Pulsed Light and Low-Level Light Therapy for the Treatment of Dry Eye: A Retrospective Before-After Study with One-Year Follow-Up.

May 31, 2021

To assess the effectiveness of a combination of intense pulsed light and low-level light therapy (IPL/LLLT) for the treatment of dry eye.Retrospective before-after single-center clinical study.Patient...

Proteoglycan 4 (PRG4) expression and function in dry eye associated inflammation.

May 31, 2021

Dry eye disease (DED) affects hundreds of millions of people worldwide. It is characterized by the production of inflammatory cytokines and chemokines as well as damaging matrix metalloproteinases (MM...

Efficacy of calcium dobesilate in treating Chinese patients with mild-to-moderate non-proliferative diabetic retinopathy (CALM-DR): protocol for a single-blind, multicentre, 24-armed cluster-randomised, controlled trial.

May 31, 2021

Calcium dobesilate (CaD) has been used in the treatment of diabetic retinopathy (DR) due to its potential in protecting against retinal vascular damage. However, there is limited evidence exploring it...

A deep learning system for detecting diabetic retinopathy across the disease spectrum.

May 31, 2021

Retinal screening contributes to early detection of diabetic retinopathy and timely treatment. To facilitate the screening process, we develop a deep learning system, named DeepDR, that can detect ear...

Analysis of progressive neovascularization in diabetic retinopathy using widefield optical coherence tomography angiography.

May 31, 2021

To quantitatively and morphologically document enlarged neovascularization elsewhere (NVE) using widefield swept-source (SS) optical coherence tomography angiography (OCTA) with vitreoretinal interfac...

Ab-externo MicroShunt versus Trabeculectomy in Primary Open-Angle Glaucoma: 1-year Results from a 2-year Randomized, Multicenter Study.

May 31, 2021

To compare the effectiveness and safety of the MicroShunt versus trabeculectomy in patients with primary open-angle glaucoma (POAG).One-year results from a 2-year, prospective, randomized, multicenter...

Semi-AI and Full-AI digitizer: The ways to digitalize visual field big data.

May 31, 2021

Glaucoma is one of the major diseases that cause blindness, which is incurable and irreversible, and it is essential to detect glaucoma vision deficits in treatment and check the progression of vision...

Sensitive period for the plasticity of alpha activity in humans.

May 31, 2021

Visual experience is crucial for the development of neural processing. For example, alpha activity development is a vision-dependent mechanism. Indeed, studies report no alpha activity is present in b...

Detection and Referral of Orbital and Ocular Injuries Associated With Intimate Partner Violence Following an Educational and Screening Initiative in an Emergency Department.

May 31, 2021

Intimate partner violence (IPV) is a substantial cause of morbidity and mortality in the US. Previous studies indicate gaps in identifying and referring female patients with IPV-associated orbital and...

Partial recovery of visual function in a blind patient after optogenetic therapy.

May 27, 2021

Optogenetics may enable mutation-independent, circuit-specific restoration of neuronal function in neurological diseases. Retinitis pigmentosa is a neurodegenerative eye disease where loss of photorec...

Utilizing a responsive web portal for studying disc tracing agreement in retinal images.

May 27, 2021

Glaucoma is a leading cause of blindness worldwide whose detection is based on multiple factors, including measuring the cup to disc ratio, retinal nerve fiber layer and visual field defects. Advances...

Axial length and its relationship to refractive error in Chinese university students.

May 27, 2021

To investigate the relationship between axial length (AL) and refractive error (RE).Participants comprised Chinese university students. In total, 894 eyes with low hyperopia to emmetropia (-0.50D ≤ ...

Distance vision, near vision and quality of life between preferred emmetropia and residual myopia in monofocal intraocular lens implantation- A Comparative study.

May 27, 2021

This study was done to evaluate the visual acuity and quality of life in predicted emmetropia (EM) and predicted residual myopia (RM) patients following phacoemulsification with monofocal intraocular ...

Distribution of near Point of Convergence, near Point of Accommodation, Accommodative Facility and Refractive Errors in a Rural Population Living in Northern Iran.

May 27, 2021

: To evaluate near point of convergence (NPC), near point of accommodation (NPA), and accommodative facility (AF) in order to determine their normative data in a rural population.: The target populati...

Impact of Graves Disease on Ocular Surface and Corneal Epithelial Thickness in Patients With and Without Graves Orbitopathy.

May 27, 2021

Our aim was to assess ocular surface and tear film stability and corneal epithelial thickness (CET) in patients with Graves disease (GD) with and without Graves orbitopathy (GO).This study included he...

The relationship between alcohol consumption and dry eye.

May 27, 2021

To assess the association between dry eye disease (DED) and alcohol consumption using a large population-based cohort.77,145 participants (19-94 years, 59% female) from the Dutch Lifelines cohort were...

New model to better diagnose dry eye disease integrating OCT corneal epithelial mapping.

May 27, 2021

To optimise the objective diagnosis of dry eye disease (DED), the capabilities of wide corneal epithelial mapping using optical coherence tomography (OCT) were studied and subsequently integrated into...

Efficacy and safety of intravitreal Fluocinolone Acetonide microimplant (ILUVIEN) in patients with chronic diabetic macular edema: 1 year follow-up.

May 27, 2021

Evaluate the efficacy and safety of intravitreal 0.19 mg fluocinolone acetonide (FAc) micro implant in patients with chronic diabetic macular edema (cDME).Prospective study recruiting subjects with ...

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