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Ophthalmology General

Prevalence of Dry Eye Disease in Africa: A Systematic Review and Meta-analysis.

Dec 03, 2020

Dry eye disease is a significant public health problem globally. The magnitude of the dry eye disease problem in Africa is, however, unknown. This study provides important and lacking information on d...

Presbyopic patient with hyperopia and moderately steep corneas: December consultation #1.

Dec 03, 2020

A 47-year-old woman was referred for refractive surgery evaluation. She has no ocular or medical history. Spectacle dependence is her chief concern. She cannot tolerate contact lens. The corrected nea...

Effect of IRT5 probiotics on dry eye in the experimental dry eye mouse model.

Dec 03, 2020

To investigate the clinical effects of IRT5 probiotics in the environmental dry eye model.Eight week old male C57BL/6 mice were randomly divided into two groups; control group (n = 16) received oral g...

Associations of serum uric acid and urinary albumin with the severity of diabetic retinopathy in individuals with type 2 diabetes.

Dec 03, 2020

Diabetic retinopathy (DR) is a serious microvascular complication of type 2 diabetes mellitus (T2DM). The aim of this retrospective study was to reveal the risk factors for the severity of DR in indiv...

Vessel Density around Foveal Avascular Zone as a Potential Imaging Biomarker for Detecting Preclinical Diabetic Retinopathy: An Optical Coherence Tomography Angiography Study.

Dec 03, 2020

: The purpose of this study was to investigate the changes of optical coherence tomography angiography (OCTA) parameters in diabetic retinopathy (DR) using an updated software with 3D projection artif...

Gut mycobiomes are altered in people with type 2 Diabetes Mellitus and Diabetic Retinopathy.

Dec 03, 2020

Studies have documented dysbiosis in the gut mycobiome in people with Type 2 diabetes mellitus (T2DM). However, it is not known whether dysbiosis in the gut mycobiome of T2DM patients would be reflect...

Secondary epiretinal membrane after Ex-Press glaucoma filtration device implant.

Dec 03, 2020

To estimate the frequency of epiretinal membrane (ERM) in eyes with primary open-angle glaucoma (POAG) treated with Ex-Press shunt implant. Secondarily, we aimed to assess the role of concomitant cata...

Rapid assessment of avoidable blindness and cataract surgery coverage among forcibly displaced Myanmar Nationals (Rohingya refugees) in Cox's Bazar, Bangladesh.

Dec 03, 2020

To determine the prevalence and causes of blindness, vision impairment and cataract surgery coverage among Rohingya refugees aged ≥ 50 years residing in camps in Cox's Bazar, Bangladesh.We used the ...

Improving statistical power of glaucoma clinical trials using an ensemble of cyclical generative adversarial networks.

Dec 03, 2020

Albeit spectral-domain OCT (SDOCT) is now in clinical use for glaucoma management, published clinical trials relied on time-domain OCT (TDOCT) which is characterized by low signal-to-noise ratio, lead...

The Utility of Routine Fundus Photography Screening for Posterior Segment Disease: A Stepped-wedge, Cluster-randomized Trial in South India.

Dec 03, 2020

To assess whether routine fundus photography (RFP) to screen for posterior segment disease at community eye clinics in South India increases referral to the urban hospital for ophthalmology care.Stepp...

Efficacy and safety evaluation of benzalkonium chloride preserved eye-drops compared with alternatively preserved and preservative-free eye-drops in the treatment of glaucoma: a systematic review and meta-analysis

Dec 02, 2020

This study is a systematic review that compared the efficacy and safety of BAK-preserved eye-drops with AP and PF eye-drops. 3 online databases were searched for randomized controlled trials. Studies...

Anterior chamber particles are associated with a reduction of intraocular pressure after selective laser trabeculoplasty

Dec 02, 2020

This study was done to examine the correlation between IOP reduction and the number of hyper-reflective particles appearing in the anterior chamber following SLT. It was a prospective interventional ...

Selective laser trabeculoplasty versus medication for open-angle glaucoma: systematic review and meta-analysis of randomized clinical trials

Dec 02, 2020

Effective treatment for OAG is to reduce the IOP, with medical therapy being the typical first-line therapy. Alternative therapy is SLT, which is safe as it is effective in lowering the IOP. Whether S...

ORCA study: real-world versus reading centre assessment of disease activity of neovascular age-related macular degeneration (nAMD)

Dec 02, 2020

The prospective, non-interventional ORCA module of the OCEAN study was done with the purpose to evaluate the quality of SD-OCT image interpretation and treatment decisions by clinicians in German. The...

Comparison of various surgical techniques for optic disc pit maculopathy: vitrectomy with the internal limiting membrane (ILM) peeling alone versus inverted ILM flap ‘plug’ versus autologous scleral ‘plug’

Dec 02, 2020

This study was done with the purpose to compare the anatomical and visual outcomes of vitrectomy with the ILM peeling alone versus inverted ILM flap to plug the pit versus autologous scleral plug for ...

Comparison of OCT angiography in children with a history of intravitreal injection of ranibizumab versus laser photocoagulation for retinopathy of prematurity

Dec 02, 2020

To compare the foveal microvascular structure characteristics in children with a history of IVR versus LP for retinopathy of prematurity by OCTA. This was a cross-sectional study. A total of 17 child...

Long-term (20-year) real-world outcomes of intravenous chemotherapy (chemo reduction) for retinoblastoma in 964 eyes of 554 patients at a single center

Dec 02, 2020

IVC remains an important global salvage therapy for retinoblastoma. This study was done with the purpose to do an evaluation of long-term globe salvage at 5, 10, 15, and 20 years following frontline I...

Effect of low-dose atropine on myopia progression, pupil diameter, and accommodative amplitude: low-dose atropine and myopia progression

Dec 02, 2020

The study was done with the purpose to evaluate the effects of 0.01% and 0.02% atropine eye drops on myopia progression, pupil diameter, and accommodative amplitude in myopic children. It was a cohor...

Comparison of central visual sensitivity between monocular and binocular testing in advanced glaucoma patients using IMO perimetry

Dec 02, 2020

This study was conducted with the purpose to compare central visual sensitivity under monocular and binocular conditions in patients with glaucoma using the new IMO static perimeter. It was a cross-s...

First-in-human continuous 24-hour measurement of intraocular pressure and ocular pulsation using a novel contact lens sensor

Dec 02, 2020

This study was done with the purpose to assess the feasibility of a novel contact lens device for intraocular pressure and ocular pulse amplitude continuous measurements over 24 hours. This was a pro...

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