Migraine/Headache

Dry needling in the management of chronic tension-type headache associated with levator scapulae syndrome: A case report.

May 01, 2024

The use of DN to the muscular trigger points and distal periosteal enthesis of the levator scapulae may be a useful adjunct intervention within a multi-modal plan of care for the management of work-re...

Primary Headache Associated with Sexual Activity: A Review of the Literature.

Feb 18, 2024

This review summarizes the evolution in diagnosis, evaluation, and treatment of primary headache associated with sexual activity (PHASA).Despite increased access to patient information and advances in...

Safety and efficacy of ubrogepant for the acute treatment of perimenstrual migraine attacks: A post hoc analysis.

Sep 01, 2023

To evaluate the efficacy and safety of ubrogepant for the acute treatment of perimenstrual migraine (pmM) attacks.Ubrogepant is an oral calcitonin gene-related peptide receptor antagonist approved for...

Levcromakalim provokes an acute rapid-onset migraine-like phenotype without inducing cortical spreading depolarization.

Jul 25, 2023

Migraine headache attacks and accompanying sensory augmentation can be induced by several agents including levcromakalim (LVC), that is also capable of provoking aura-like symptoms in migraineurs. We ...

Migraine Treatment Using Erenumab: Can Lead to a Cognitive and Psychological Qualitative Improvement?

May 29, 2023

Migraine is one of the most disabling disorders in the world, associated with poor quality of life. Migraine prevention strategies have increasingly evolved since monoclonal antibodies against the cal...

Integrating eQTL and GWAS data characterises established and identifies novel migraine risk loci.

May 29, 2023

Migraine-a painful, throbbing headache disorder-is the most common complex brain disorder, yet its molecular mechanisms remain unclear. Genome-wide association studies (GWAS) have proven successful in...

Sleep of migraine patients is ameliorated by ketogenic diet, independently of pain control.

May 22, 2023

Migraine patients are frequently affected by sleep complaints. The ketogenic diet (KD) is an option for the treatment of migraine. Our aim was: 1) to assess the effects of KD on sleep complaints in pa...

Safety and efficacy of rimegepant orally disintegrating tablet for the acute treatment of migraine in China and South Korea: a phase 3, double-blind, randomised, placebo-controlled trial.

May 22, 2023

No acute treatments targeting calcitonin gene-related peptide (CGRP) have been approved for use in China or South Korea. We aimed to compare the efficacy and safety of rimegepant-an orally administere...

Defining a Migraine Day: Adjusting Criteria to Include 30-Minute Migraines

May 16, 2023

Using a headache duration of 30 or more minutes, rather than 4 or more hours, resulted in a 5.4% increase in monthly migraine days. “Having a standardized definition for a migraine day is cri...

Head-to-Head Analysis Compares 25 Migraine Medications

May 15, 2023

In a big-data analysis of 25 acute migraine medications, triptans, ergots, and anti-emetics emerged as the most effective medications. In a big-data analysis simultaneously comparing 25 acute m...

Atogepant Effective for Preventing Treatment-Resistant Episodic Migraine

May 15, 2023

In ELEVATE, atogepant was effective in preventing difficult-to-treat episodic migraine among patients with previous failure of multiple preventive medications. Atogepant is an oral calcitonin g...

Associations between anxiety, depression with migraine, and migraine-related burdens.

May 15, 2023

Anxiety and depression are the most common psychiatric comorbidities in migraine, but their impact on the risk of developing migraine and their gender and age differences are unclear, and research on ...

Zavegepant Nasal Spray Safe & Effective for Acute Migraine

May 08, 2023

Zavegepant nasal spray was effective for acute migraine, demonstrating onset of efficacy as early as 15 minutes post-dose and a favorable safety profile. Non-oral acute therapies for migraine a...

Headache in patients with inflammatory bowel disease: Migraine prevalence according to the Migraine Screening-Questionnaire (MS-Q) and headache characteristics.

May 08, 2023

The gut-brain axis describes a complex bidirectional association between neurological and gastrointestinal (GI) disorders. In patients with migraine, GI comorbidities are common. We aimed to evaluate ...

Targeting the intrinsically photosensitive retinal ganglion cell to reduce headache pain and light sensitivity in migraine: A randomized double-blind trial.

May 08, 2023

Approximately 80% of patients with migraine report light sensitivity during attacks and almost half report that following headache, light sensitivity is the most bothersome symptom. Light wavelengths ...

Nearly Half of Patients With Vertigo Have History of Migraine

May 03, 2023

Migraine may represent a risk factor for benign paroxysmal positional vertigo and could explain why some cases of vertigo occur in younger patients. Benign paroxysmal positional vertigo (BPPV) ...

Characterisation of the management of patients with migraine in the primary care setting in Spain. Analysis of the results of the European My-LIFE anamnesis project.

May 01, 2023

Migraine affects more than 4.5 million people in Spain, resulting in a considerable socioeconomic impact. Although national and international guidelines have been published, the management of patients...

Analysis of headache management in Andalusia.

May 01, 2023

Headache is a frequent reason for consultation between primary care physicians, emergency services physicians, and neurology specialists; however, it is not always well managed. The Andalusian Society...

Clinical benefits and economic cost-savings of Remote Electrical Neuromodulation (REN) for migraine prevention.

Apr 24, 2023

Assess the clinical benefits and associated direct and indirect cost-savings from Remote Electrical Neuromodulation (REN) for migraine prevention.REN, a prescribed, wearable, FDA-cleared neuromodulati...

Cerebral blood flow in children with persisting postconcussive symptoms and posttraumatic headache at 2 weeks postconcussion.

Apr 24, 2023

Persisting postconcussive symptoms (pPCS), particularly headache, can significantly disrupt children's recovery and functioning. However, the underlying pathophysiology of these symptoms remains uncle...