Dementia
May 01, 2024
Gamma-hydroxy-butyric acid (GABA) and glutamate are neurotransmitters with essential importance for cognitive processing. Here, we investigate relationships between GABA, glutamate, and brain ß-amylo...
Feb 18, 2024
Previous studies on Alzheimer's disease-type cognitive impairment (ADCI) and subcortical vascular cognitive impairment (SVCI) has rarely explored spatiotemporal heterogeneity. This study aims to ident...
Feb 18, 2024
Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the most common cause of dementia in the elderly worldwide. The exact etiology of AD, particularly its genetic mechanisms, rema...
Nov 15, 2023
During the three decades since the publication of ICD-10 in 1992 and the initial implementation of ICD-11 in 2022, much clinical and research data have been accumulated concerning the various types of...
Sep 01, 2023
Neuropsychiatric symptom could be useful for detecting patients with prodromal dementia. Similarities and differences in the NPSs between preclinical/prodromal Alzheimer's disease (AD) and prodromal P...
Jul 25, 2023
Motor fluctuations are a significant driver of healthcare resource utilization (HCRU) in people with Parkinson's (PwP). A common management strategy is to include Catechol-O-methyl transferase (COMT) ...
Jul 25, 2023
Patients with Parkinson's disease (PD) exhibit widespread brain perfusion changes.This study investigated whether cerebral regions with hypoperfusion and hyperperfusion have differential effects on mo...
May 29, 2023
This cross-sectional study aimed to assess the adverse effects of pesticide use in humans, such as non-communicable diseases, using acetylcholinesterase (AChE) and pesticide concentrations in blood sa...
May 22, 2023
Whole-plant medical cannabis (MC) products are widely used for controlling symptoms associated with Parkinson's disease (PD). Despite its widespread use, few studies have investigated the long-term im...
May 22, 2023
Little is known about the impact of plasma exchange (PE) on clinical laboratory parameters in Alzheimer's disease (AD) patients.AD patients in the AMBAR trial (N = 322) received weekly therapeutic...
May 15, 2023
Patients with Parkinson's disease often suffer from OFF symptoms disrupting their daily routines and adding to disabilities. Despite polypharmacy and adjustments to medication schedules, they often do...
May 15, 2023
Behavioral and psychological symptoms of dementia (BPSD) profiles vary depending on etiology in patients with mild-to-moderate BPSD. It is not known if similar differences exist in patients with sever...
May 12, 2023
The following is a summary of the “Late-life depression, allostatic load, and risk of dementia: The AGES-Reykjavik study,” published in the February 2023 issue of Psychoneuroendocrinology by Twait...
May 11, 2023
The following is a summary of the “Time-dependent effects of acute stress on working memory performance: A systematic review and hypothesis,” published in the February 2023 issue of Psychoneuroend...
May 08, 2023
Hand dysfunctions in Parkinson's disease include rigidity, muscle weakness, and tremor, which can severely affect the patient's daily life. Herein, a multimodal sensor glove is developed for quantifyi...
May 08, 2023
55 million people worldwide suffer from Alzheimer's disease (AD). A definitive diagnosis of AD is made postmortem after a neuropathological examination of the brain. There is an urgent need for an inn...
May 01, 2023
Alzheimer's disease (AD) is a common neurodegenerative disease characterized by amyloid plaques and impaired brain metabolism. Because women have a higher prevalence of AD than men, sex differences ar...
May 01, 2023
Lead (Pb) is a known environmental risk factor in the etiology of Alzheimer's disease (AD). The existing reports suggest that Pb exposure increases beta-amyloid (Aβ) levels in brain tissues and cereb...
Apr 24, 2023
In Alzheimer's disease (AD), the presence of circadian dysfunction is well-known and may occur early in the disease course. The melanopsin retinal ganglion cell (mRGC) system may play a relevant role ...
Apr 24, 2023
The olfactory bulb (OB) plays a fundamental role in the sense of smell and has been implicated in several pathologies, including Alzheimer's disease. Despite its importance, high metabolic activity, a...