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Critical Care General

Effects of inhalation of multi-walled carbon nanotube (MWCNT) on respiratory syncytial virus (RSV) infection in mice.

Jul 03, 2023

Multi-walled carbon nanotubes (MWCNTs), a kind of nanomaterial, are widely used in battery electrodes and composite materials, but the adverse effects associated with their accumulation in the living ...

Help is on the way: critical roles of CD4 T cells in infection and vaccination.

Jul 03, 2023

The July 2023 issue contains a Special Feature about CD4 T cells in infection and vaccination. CD4 T helper cells are composed of many specialized subsets that play critical roles in immune memory. Th...

Gender and racial differences in first and senior authorship of high-impact critical care randomized controlled trial studies from 2000 to 2022.

Jul 03, 2023

Females and ethnic minorities are underrepresented in the first and senior authorships positions of academic publications. This stems from various structural and systemic inequalities and discriminati...

A new assessment method for right ventricular diastolic function using right heart catheterization by pressure-volume loop.

Jul 03, 2023

Diastolic stiffness coefficient (β) and end-diastolic elastance (Eed) are ventricular-specific diastolic parameters. However, the diastolic function of right ventricle had not been investigated suffi...

Schisandrin B Protects against Ischemic Brain Damage by Regulating PI3K/AKT Signaling in Rats.

Jun 26, 2023

To explore the effect and mechanism of schisandrin B (Sch B) in the treatment of cerebral ischemia in rats.The cerebral ischemia models were induced by middle cerebral artery occlusion (MCAO) and repe...

White Matter Hyperintensity as a Vascular Contribution to the AT(N) Framework.

Jun 26, 2023

The AT(N) framework enables the classification of an individual within the biological Alzheimer's disease (AD) continuum by pairing the cognitive stage with the biomarker status of amyloid-beta (Aβ, ...

Clearance of intracellular bacterial infections by hyaluronic acid-based ROS responsive drug delivery micelles.

Jun 26, 2023

Pathogenic bacteria residing inside cells could cause disruption of cellular metabolic balance. Therefore, basing on high oxidative stress response of the intracellular bacteria infected micro-environ...

[Diagnosis and treatment of 26 cases of adenovirus infection after allogeneic hematopoietic stem cell transplantation].

Jun 26, 2023

To analyze the clinical characteristics and prognosis of adenovirus infection after allogeneic hematopoietic stem cell transplantation. A total of 26 patients with adenovirus infection admitted to t...

[Reducing the risk of infections in hereditary and acquired complement deficiencies.].

Jun 26, 2023

Hereditary complement deficiencies are relatively rare worldwide, they account for about 1-10% of primary immunodeficiencies. Acquired complement deficiencies are more prevalent and with the more freq...

Effects of implementation of healthcare associated infection surveillance and interventional measures in the neonatal intensive care unit: Small steps matter.

Jun 26, 2023

Neonatal sepsis has been a global concern considering the mortality and morbidity. This study was undertaken to determine the effects of implementation of interventions namely healthcare associated in...

Therapeutic Effect of a Hydrogel-based Neural Stem Cell Delivery Sheet for Mild Traumatic Brain Injury.

Jun 26, 2023

There are no effective clinically applicable treatments for neuronal dysfunction after mild traumatic brain injury (TBI). Here, we evaluated the therapeutic effect of a new delivery method of mouse ne...

Headache features in people with whiplash associated disorders: A scoping review.

Jun 26, 2023

Whiplash-associated headache (WAH) is one of the most common symptoms after a whiplash injury, leading to high disability. Nevertheless, the clinical characteristics of WAH have not been well describe...

[Feasibility and safety of transseptal transcatheter mitral valve replacement for severe mitral regurgitation].

Jun 26, 2023

A prospective, single-center, single-arm, and open-design study was performed to evaluate the feasibility and safety of transseptal transcatheter mitral valve replacement in the treatment of severe mi...

Soluble CD4 effectively prevents excessive TLR activation of resident macrophages in the onset of sepsis.

Jun 19, 2023

T lymphopenia, occurring in the early phase of sepsis in response to systemic inflammation, is commonly associated with morbidity and mortality of septic infections. We have previously shown that a su...

Slower clozapine titration than the official Japanese protocol led to fewer inflammatory adverse effects: A retrospective chart review of seven hospitals.

Jun 19, 2023

Higher frequencies of inflammatory adverse effects of clozapine have been reported in Japan. As the international titration protocol for Asians has set slower dose titration than the Japanese package ...

Nosocomial outbreak caused by Serratia marcescens in a neonatology intensive care unit in a regional hospital. Analysis and improvement proposals.

Jun 19, 2023

Serratia marcescens (SM) may cause nosocomial outbreaks in Neonatal Intensive Care Units (NICU). We describe an outbreak of SM in a NICU and propose additional prevention and control recommendations.B...

Comorbidity and risk of infection among patients with hip fracture: a Danish population-based cohort study.

Jun 19, 2023

Impact of comorbidity on infection risk among hip fracture patients is unclear. We found high incidence of infection. Comorbidity was an important risk factor for infection up to 1 year after surgery....

The Evaluation, Classification and Management of Septic Arthritis of the Shoulder: The Comprehensive Shoulder Sepsis System.

Jun 19, 2023

Septic arthritis of the shoulder is distinctly challenging to diagnose and treat. Guidelines for appropriate workup and management are limited and do not account for the variations in clinical present...

In-Hospital Amantadine Does Not Improve Outcomes After Severe Traumatic Brain Injury: An 11-Year Propensity-Matched Retrospective Analysis.

Jun 19, 2023

Disruption of dopamine neurotransmission is associated with functional impairment after severe traumatic brain injury (sTBI). This has prompted the study of dopamine agonists, such as amantadine, to a...

Cardiac MRI-based right-to-left ventricular blood pool T2 relaxation times ratio correlates with exercise capacity in patients with chronic heart failure.

Jun 19, 2023

MRI T2 mapping has been proven to be sensitive to the level of blood oxygenation. We hypothesized that impaired exercise capacity in chronic heart failure is associated with a greater difference betwe...

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