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Critical Care General

Zika & Heart: A systematic review: Zika & Heart.

Nov 23, 2020

Zika virus infection affects more than 80 countries in the world, mainly those with a tropical climate. Although the most frequent clinical presentation is characterized by rash, conjunctivitis, myalg...

Worsening Racial Disparities in Patients Undergoing Anatomic and Reverse Total Shoulder Arthroplasty in the United States.

Nov 23, 2020

The most comprehensive healthcare policy changes aimed at reducing racial disparities were implemented in 2011 and continue today. It is unknown if these initiatives have led to a decrease in racial d...

Dexmedetomidine exerts cardioprotective effect through miR-146a-3p targeting IRAK1 and TRAF6 via inhibition of the NF-κB pathway.

Nov 23, 2020

Myocardial ischemia/reperfusion (I/R) injury is a common cause of mortality. Cardiac miR-146a is emerging as a potent regulator of myocardial function. Dexmedetomidine preconditioning provides cardiop...

Strain-Guided Management of Potentially Cardiotoxic Cancer Therapy.

Nov 23, 2020

In patients at risk of cancer therapy-related cardiac dysfunction (CTRCD), initiation of cardio-protective therapy (CPT) is constrained by the low sensitivity of EF for minor changes in LV function. G...

Pneumonia in medical professionals during COVID-19 outbreak in cardiovascular hospital.

Nov 23, 2020

The pandemic of coronavirus associated disease (COVID-19) placed the health care workers at high risk. We investigated clinical and treatment characteristics of infected medical professionals in a car...

Left ventricular circumferential strain and coronary microvascular dysfunction: A report from the Women's Ischemia Syndrome Evaluation Coronary Vascular Dysfunction (WISE-CVD) Project.

Nov 19, 2020

Women with ischemia but no obstructive coronary artery disease (INOCA) often have coronary microvascular dysfunction (CMD). Left ventricular (LV) circumferential strain (CS) is often lower in INOCA co...

Treatment of Cognitive Impairment and the Role of Demographic Factors in Disease Progression: The Final Results of the Russian Observational Program "DIAMANT".

Nov 19, 2020

Chronic cerebral ischemia (CCI) is a form of cerebrovascular disease manifested as a vascular cognitive impairment (VCI). The management of the patients with CCI is determined by a healthy lifestyle a...

Clinical profile and predictors of in-hospital mortality among older patients admitted for COVID-19.

Nov 19, 2020

The coronavirus disease 2019 (COVID-19) is characterized by poor outcomes and mortality, particularly in older patients.Post-hoc analysis of the international, multicentre, "real-world" HOPE COVID-19 ...

A Giant Right-Heart Thrombus-in-Transit in a Patient with COVID-19 Pneumonia.

Nov 19, 2020

BACKGROUND Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread to more than 200 countries across the world. Studies have shown that pa...

Angiopoietin-2 is released during anaphylactic hypotension in anesthetized and unanesthetized rats.

Nov 19, 2020

Angiopoietin (Angpt)-2, a permeability-increasing growth factor, is involved in vascular leakage of sepsis and acute lung injury, and could be released from endothelium in response to anaphylaxis-rela...

Correlation Between Quantitative Assessment of Chest Computed Tomography (CT) Imaging and Prognosis of COVID-19 Patients.

Nov 19, 2020

BACKGROUND The aim of our work was to evaluate the correlation between the quantitative parameters of the peak lesion to 25% improvement time (PIT25) and the prognosis of new coronavirus pneumonia (CO...

Association of SARS-CoV-2 genomic load trends with clinical status in COVID-19: A retrospective analysis from an academic hospital center in New York City.

Nov 19, 2020

The Infectious Diseases Society of America has identified the use of SARS-CoV-2 genomic load for prognostication purposes as a key research question. We designed a retrospective cohort study that incl...

Differential diagnosis and prospective grading of COVID-19 at the early stage with simple hematological and biochemical variables.

Nov 19, 2020

We evaluated simple laboratory variables to discriminate COVID-19 from bacterial pneumonia or influenza and for the prospective grading of COVID-19. Multivariate logistic regression and receiver opera...

[Effect of early intervention bundle on clinical prognosis of patients with latent/overt septic shock in emergency department].

Nov 19, 2020

To observe the effect of early intervention bundle on clinical prognosis of patients with latent/overt septic shock in emergency department and analyze the risk factors for mortality.Patients with lat...

Collateral damages in the SARS-CoV-2 pandemia- two cases.

Nov 19, 2020

At present, "severe acute respiratory syndrome new coronavirus" (SARS-CoV-2) affects the whole world and has led to a pandemia with almost 2.000.000 infected patients in the mid of April 2020 (WHO). T...

High value of Mid-regional proAdrenomedullin in COVID-19: a marker of widespread endothelial damage, disease severity and mortality.

Nov 19, 2020

The widespread endothelial damage due to severe acute respiratory syndrome Coronavirus 2 (SARS-CoV2) may lead to a disruption of the adrenomedullin (ADM) system responsible for vascular leakage, incre...

Deployment and Psychological Correlates of Suicide Ideation: A Prospective, Longitudinal Study of Risk and Resilience Among Combat Veterans.

Nov 19, 2020

Suicide rates among military personnel have risen in part due to war zone deployments. Yet, the degree to which deployment-related stressors, in combination with preexisting and co-occurring psychiatr...

p75NTR Promotes Astrocyte Proliferation in Response to Cortical Stab Wound.

Nov 19, 2020

Astrogliosis after brain trauma can have a significant impact on functional recovery. However, little is known about the mechanisms underlying astrocyte proliferation and subsequent astrogliosis. In t...

The Effect of Temperature Increases on Brain Tissue Oxygen Tension in Patients with Traumatic Brain Injury: A Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury Substudy.

Nov 19, 2020

Fever may aggravate secondary brain injury after traumatic brain injury (TBI). The aim of this study was to identify episodes of temperature increases through visual plot analysis and algorithm suppor...

An Electronically Delivered, Patient-Activation Tool for Intensification of Medications for Chronic Heart Failure with Reduced Ejection Fraction: The EPIC-HF Trial.

Nov 19, 2020

Major gaps exist in the routine initiation and dose up-titration of guideline-directed medical therapies (GDMT) for patients with heart failure with reduced ejection fraction (HFrEF). Without novel a...

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