The following is a summary of “Effect of overall lifestyle on the all-cause mortality and cardiovascular disease death in dyslipidemia patients with or without lipid-lowering therapy: a cohort study,” published in the September 2023 issue of Cardiology by Wang et al.
Lifestyle changes can help manage dyslipidemia. Researchers conducted a retrospective study to investigate the effect of overall lifestyle on all-cause mortality and cardiovascular disease (CVD) death in dyslipidemia patients with or without lipid-lowering therapy.
They assessed overall lifestyle using the Mediterranean diet score, physical activity, smoking status, sleep duration, and body mass index (BMI) with data from the National Health and Nutrition Examination Survey (NHANES). The Multivariate Cox regression model was utilized to look into the impact of the overall lifestyle score on the risk of all-cause mortality and CVD death. The analysis reported hazard ratios (HR) with 95% CI.
The results showed 11,549 dyslipidemia patients. An optimal overall lifestyle was linked to a lower risk of all-cause mortality (HR = 0.47, 95%CI: 0.34–0.64) and CVD death (HR = 0.45, 95%CI: 0.22–0.94) for those not receiving lipid-lowering therapy. Patients using lipid-lowering therapy exhibited similar findings (all-cause mortality: HR = 0.45, 95% CI: 0.33–0.62; CVD death: HR = 0.38, 95%CI: 0.23–0.63).
They concluded that a favorable overall lifestyle is associated with improved dyslipidemia prognosis.
Source: bmccardiovascdisord.biomedcentral.com/articles/10.1186/s12872-023-03450-1