To compare the stress level in parents of children with new-onset type 1 diabetes receiving a fixed insulin dose for a fixed range of carbohydrates (CHOs) to parents of children receiving a precise insulin dose for a precise number of CHOs using an insulin-to-carbohydrate ratio (ICR).
Twenty-four participants (8-14 years) were randomized to receive a fixed dose of insulin for a fixed range of CHOs (FD group) or a precise dose of insulin for a precise number of carbohydrates using an ICR (ICR group). The primary endpoint was parental stress measured with the parental stress survey (PSS) one to four months after diagnosis. Secondary endpoints included glycemic variability, glycated hemoglobin (HbA ), and safety.
Compared to parents of children in the ICR group, those from the FD group reported less stress during the first four months after diagnosis (p = 0.022). Glycemic variability and HbA were similar in both groups. None of the patients from either group required an emergency department visit or hospitalization.
In comparison to precise insulin dosing using an ICR, fixed insulin dosing for a fixed range of CHOs may be less stressful for parents to learn and employ when initially taught diabetes management skills for their child with new-onset type 1 diabetes.

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