The decrease in Oxygen Reserve Index (ORI) provides a prediction for the development of hypoxemia and hyperoxia. Our aim is to determine the effect of ORI-guided oxygen titration on hyperoxemia-mediated morbidity.
Consecutive 120 ASA I-III patients, 18-70 years of age, without severe obstruction or restriction, undergoing one lung ventilation (OLV), were included. Patients were divided into 4 groups. Oxygen titration without ORI monitoring with low-flow anesthesia (n=25) and high-flow anesthesia (n=28). Oxygen titration by ORI monitoring with low flow anesthesia (n=25) and high flow anesthesia (n=25). OLV time, duration of surgery and anesthesia, oxygen application time over 60%, vital signs, hospital and ICU stay time and complications were recorded.
There was a significant difference in terms of FiO2 used during OLV (p< 0.05). There was no difference in ORI values (p <0.05). In Group 3, both PaO2 and SpO2 were significantly lower than the others both before and during OLV. There was no significant difference in ORI parameters between low and high flow anesthesia groups. There was a strong, positive correlation between the duration of hospital stay and FiO2 used above 80% during OLV.
We concluded that ORI-guided thoracic anesthesia may reduce hospital stay and increase patient safety.

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