The following is a summary of “Orthostatic variation of pulmonary artery pressure in ambulatory heart failure patients,” published in the October 2023 issue of Cardiology by Sethi et al.
Researchers retrospectively evaluated the effect of positional change (supine to standing) on pulmonary artery pressure (PAP) in ambulatory heart failure (HF) patients.
They enrolled seventeen patients with CardioMEMS® sensors and stable heart failure. Supine and standing measurements were taken, with a minimum of 5 minutes between the two positions. These measurements involved PAP readings using the manufacturer’s handheld interrogator to collect 10-second data and recordings of systemic blood pressure and heart rate.
The results showed mean supine and standing values and their differences (Δ) as Systolic PAP were 33.4 (± 11.19) and 23.6 (± 10), with Δ of 9.9 mmHg (P=0.0001); diastolic PAP was 14.2 (± 5.6) and 7.9 (± 5.7), with Δ of 6.3 mmHg (P=0.0001); mean PAP was 21.8 (± 7.8) and 14 (± 7.2), with Δ of 7.4 mmHg (P=0.0001), while systemic blood pressure showed no significant variation.
Investigators conclude that ambulatory heart failure patients experienced a mean decline in pulmonary artery pressure (PAP) with a standing of 6.3 mmHg in diastolic PAP, 9.9 mmHg in systolic PAP, and 7.4 mmHg in mean PAP.
Source: bmccardiovascdisord.biomedcentral.com/articles/10.1186/s12872-023-03534-y
