This study was done with the purpose to assess the feasibility of a novel contact lens device for intraocular pressure and ocular pulse amplitude continuous measurements over 24 hours.
This was a prospective, open-label, single-center, non-randomized study. It included glaucoma and healthy subjects so that the outcomes can be compared. IOP and OPA values acquired by the PMCL device in one patient’s eye at the beginning of the measurement were compared with tonometry values and DCT in the same eye just before PMCL placement. Furthermore, IOP and OPA values measured with PMCL on the study eye during a WDT were compared with DCT values in the fellow eye. Comparisons were performed using t-tests with 95% Confidence Intervals.
24 hour IOP and OPA curves were obtained for eight subjects. Differences between PMCL and DCT for IOP variations in fellow eyes were within ±5 mm Hg for 97.2% of time points. The difference between OPA in fellow eyes was within ±5 mm Hg for 85.5% of the time points.
This study provided a proof-of-concept for 24-hour continuous measurements of IOP and OPA with the PMCL through its findings. This device is non-invasive and has good compatibility with standard tonometry.
Reference: https://bjo.bmj.com/content/104/11/1519
