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Surgery General

Detection of non-reciprocal/reciprocal ALK translocation as poor predictive marker in first-line crizotinib-treated ALK-rearranged non-small cell lung cancer patients.

Mar 02, 2020

During non-reciprocal/reciprocal translocation process, 5'-ALK sometimes get retained in the genome and are detectable by next-generation sequencing (NGS); however, no report have investigated its cli...

The significance of epidermal growth factor receptor uncommon mutations in non-small cell lung cancer: A systematic review and critical appraisal.

Mar 02, 2020

Uncommon epidermal growth factor receptor (EGFR) mutations collectively account for 10% of EGFR mutations, harboring heterogeneous molecular alterations within exons 18-21 with clinically variable res...

Phase distribution of polycyclic aromatic hydrocarbons and their oxygenated and nitrated derivatives in the ambient air of a Brazilian urban area.

Mar 02, 2020

Air quality in large cities has worsened in recent years as a consequence people's health is directly affected. Among the toxic compounds released to environmental air are polycyclic aromatic hydrocar...

Insight into the binding behavior of ceritinib on human α-1 acid glycoprotein: Multi-spectroscopic and molecular modeling approaches.

Mar 02, 2020

Ceritinib is a second-generation anaplastic lymphoma kinase (ALK) inhibitor for mainly treating non-small cell lung cancer (NSCLC). This investigation focused on to clarify in detail the binding behav...

Neocortical morphometry in Huntington's disease: Indication of the coexistence of abnormal neurodevelopmental and neurodegenerative processes.

Mar 02, 2020

Huntington's disease (HD) is an inherited, autosomal dominant disorder that is characteristically thought of as a degenerative disorder. Despite cellular and molecular grounds suggesting HD could also...

Polyomavirus and Cytomegalovirus Infections are Risk factors for Grafts Loss in Simultaneous Pancreas and Kidney Transplant.

Mar 02, 2020

Published literature on predictors of Polyomavirus (BKV) and Cytomegalovirus (CMV) infections in Simultaneous Pancreas and Kidney (SPK) transplant and their impact on allograft outcomes remains sparse...

Incidence of nephrogenic systemic fibrosis after administration of gadoteric acid in patients on renal replacement treatment.

Mar 02, 2020

Nephrogenic system fibrosis (NSF) is a rare complication detected in patients with renal insufficiency exposed to gadolinium-based contrast agents (GBCAs). The aim of our study is to evaluate the prev...

Improved Mycobacterium tuberculosis clearance after restoration of IFN-γ TNF-α CD4 T cells: Impact of PD-1 inhibition in active tuberculosis patients.

Mar 02, 2020

Prolonged therapy, drug toxicity, non-compliance, immune suppression and alarming emergence of drug resistance necessitate the search for therapeutic vaccine strategies for tuberculosis (TB). Such str...

Cryosurgery for basal cell carcinoma treated in primary care.

Mar 02, 2020

Basal cell carcinoma (BCC) is a very common skin cancer in Caucasians. Although rarely life-threatening, it can be locally destructive and consumes a considerable amount of health expenditure. Treatme...

Safety and Accuracy of Factory Calibrated Continuous Glucose Monitoring in Pediatric Patients Undergoing Hematopoietic Stem Cell Transplantation.

Feb 28, 2020

Pediatric patients undergoing hematopoietic stem cell transplant (HSCT) may be at risk for malglycemia and adverse outcomes including infection, prolonged hospital stays, organ dysfunction, graft-vers...

Prior and peri-operative revascularization does not affect survival in lung transplant patients.

Feb 28, 2020

Coronary artery disease is common in lung transplant patients and has historically been viewed as a contraindication to the procedure. Although this mindset is changing, the effect of prior or peri-op...

Dietary intake and Diet Quality of Hematopoietic Stem Cell Transplant Survivors.

Feb 28, 2020

Hematopoietic stem cell transplant (HCT) survivors are burdened by a high prevalence and early onset of chronic disease. Healthy dietary patterns have been associated with lower risks of chronic healt...

Association Between Living Kidney Donor Postdonation Hypertension and Recipient Graft Failure.

Feb 28, 2020

Recipients of kidneys from living donors who subsequently develop end-stage renal disease (ESRD) also have higher graft failure, suggesting the 2 donor kidneys share risk factors that could inform rec...

The Renal Resistive Index in Allografts: Is Sonographic Assessment Sufficiently Reproducible in a Routine Clinical Setting? - Reproducibility of the Renal Resistive Index.

Feb 28, 2020

 To assess the reproducibility of the renal resistive index (RRI) in a routine clinical setting. 22 patients with a kidney allograft and 19 physicians participated in our prospective study. Within...

Effect of direct angioplasty therapy on acute middle cerebral artery occlusion with good leptomeningeal collateral.

Feb 28, 2020

The objective of this study was to investigate and discuss the effect of direct angioplasty therapy on acute middle cerebral artery occlusion (MCAO) patients with good leptomeningeal collateral circul...

Association of postoperative complications and outcomes following coronary artery bypass grafting.

Feb 28, 2020

The long-term effects of postoperative complications following coronary artery bypass grafting (CABG) are unknown.Medicare-linked records from the Society of Thoracic Surgeons Adult Cardiac Surgery Da...

A Decomposition Method to Assess the Contributions of Geographic and Nongeographic Factors to White-Black Disparities in Health Care.

Feb 28, 2020

Black-white gaps in high-quality hospital use are documented, but the relative contributions of various factors are unclear. The objective of this study was to quantify the contributions of difference...

A Report on the Representation of Women in Academic Plastic Surgery Leadership.

Feb 28, 2020

The year 2017 marked the first year women comprised a majority of U.S. medical school matriculants. While more women are pursuing surgical training, within plastic surgery, there is a steady attrition...

Scarless Neck Feminization: Transoral Transvestibular Approach Chondrolaryngoplasty.

Feb 28, 2020

Chondrolaryngoplasty or reduction of laryngeal prominence is a gender affirmation surgery for transgender women, or for male patients desiring an aesthetic surgery. Several variations of the procedur...

Transbrow Excision Blepharoplasty for Upper Eyelid Dermatochalasis: A Modified Approach.

Feb 28, 2020

Many aging women with upper lid dermatochalasis pluck their lower lateral eyebrows to combat lateral drooping. The authors present and evaluate outcomes of a modified excision blepharoplasty method pe...

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