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Surgery General

Serum albumin level difference in burn injury after tangential excision: A prospective cohort study.

Mar 10, 2020

Tangential excision in burn patients results in blood loss, with an average of 100 ml per 1% total body surface area (TBSA) excised. This substantial blood loss will be accompanied by decreasing seru...

Jigsaw Group-Based Learning in Difficult Airway Management: An Alternative Way to Teach Surgical Didactics.

Mar 10, 2020

We describe the effectiveness of the Jigsaw method in the instruction of residents in difficulty airway management.The residents were given a pre-Jigsaw instruction test and a self-assessment of their...

Adherence to the National Comprehensive Cancer Network Criteria of Complete Circumferential Peripheral and Deep Margin Assessment in Treatment of High-Risk Basal and Squamous Cell Carcinoma.

Mar 10, 2020

The National Comprehensive Cancer Network (NCCN) has established guidelines for the treatment of keratinocyte carcinomas (KCs). Complete circumferential peripheral and deep margin assessment (CCPDMA) ...

Findings, Phenotypes, Diagnostic Accuracy, and Treatment in Freeman-Burian Syndrome.

Mar 10, 2020

Freeman-Burian syndrome (FBS) is a rare congenital myopathic craniofacial syndrome. Since publication of the genotype-correlated clinical diagnostic criteria, no complete survey of the literature has ...

Long-term follow-up of osteomyelitis caused by Bacille Calmette-Guérin vaccination in immunocompetent children.

Mar 10, 2020

No standard treatment for Bacille Calmette-Guérin (BCG)-associated osteomyelitis, a rare but serious complication of the BCG vaccine, has been established. This study explored the short- and long-ter...

A Qualitative Study of the Operating Room Experience of Patients That Underwent Surgery under Spinal Anesthesia: "It Was Like an Adventure".

Mar 10, 2020

This study aimed to explore the experiences of the patients that underwent orthopedic surgery under spinal anesthesia and to report their feelings and thoughts. The study was carried out using a quali...

Effects of Novel Laser Dental Implant Microtopography on Human Osteoblast Proliferation and Bone Deposition.

Mar 10, 2020

The aim of this study was to compare how two innovative laser titanium surfaces and sandblasted and acid-etched surfaces influence human osteoblast behavior during osteogenesis and the initial phases ...

How Does Cadaveric Simulation Influence Learning in Orthopedic Residents?

Mar 10, 2020

The objectives of this study were to understand how cadaveric simulation impacts learning in orthopedic residents, why it is a useful training tool, and how skills learnt in the simulated environment ...

N -methyladenosine Reader Protein Ythdc2 Suppresses Liver Steatosis via Regulation of mRNA Stability of Lipogenic Genes.

Mar 10, 2020

Non-alcoholic fatty liver disease (NAFLD) is characterized by accumulation of excessive triglycerides (TGs) in hepatocytes. Obesity is a major risk factor for developing fatty liver, although the intr...

Comparing TEE vs Non-TEE guided cardioversion of atrial fibrillation: the ENSURE-AF trial.

Mar 10, 2020

ENSURE-AF (NCT02072434) assessed therapy with edoxaban versus enoxaparin-warfarin in patients with nonvalvular atrial fibrillation (AF) undergoing elective electrical cardioversion (ECV).To evaluate c...

Tuning Cytokines Enriches Dendritic Cells and Tregs in the Periodontium.

Mar 10, 2020

Periodontal disease results from the pathogenic interactions between the tissue, immune system, and microbiota; however, standard therapy fails to address the cellular mechanism underlying the chronic...

Infectious complications after hematopoietic stem cell transplantation for primary immunodeficiency in children: a multicenter nationwide study.

Mar 10, 2020

The aim of this nation-wide study was to evaluate the characteristics of bacterial (BI), invasive fungal disease (IFD) and viral infections (VI) in pediatric patients with PID after allogeneic hematop...

Evaluation of preoperative prognostic factors in patients with resectable invasive intraductal papillary mucinous carcinoma.

Mar 10, 2020

Upfront surgery is the standard treatment for resectable invasive intraductal papillary mucinous carcinoma; however, recurrence is common. Therefore, we investigated the recurrence, surgical outcome, ...

Does Postoperative Cognitive Decline Result in New Disability After Surgery?

Mar 10, 2020

Establish whether POCD is associated with new disability after surgery, which would inform whether POCD impacts patient-centered outcomes.POCD is a decline in neuropsychiatric tests scores from presur...

Textbook Outcome and Survival in Patients With Gastric Cancer: An Analysis of the Population Registry of Esophageal and Stomach Tumours in Ontario (PRESTO).

Mar 10, 2020

To examine the association between Textbook Outcome (TO)-a new composite quality measurement-and long-term survival in gastric cancer surgery.Single-quality indicators do not sufficiently reflect the ...

Cumulative Effect of Flexible Duty-hour Policies on Resident Outcomes: Long-term Follow-up Results From the FIRST Trial.

Mar 10, 2020

To investigate the long-term effect of flexible duty-hour policies on resident outcomes BACKGROUND:: The Flexibility in Duty Hour Requirements for Surgical Trainees trial showed no significant differe...

Variants in Epithelial-Mesenchymal Transition and Immune Checkpoint Genes Are Associated With Immune Cell Profiles and Predict Survival in Non-Small Cell Lung Cancer.

Mar 10, 2020

Identification of gene mutations that are indicative of epithelial-mesenchymal transition and a noninflammatory immune phenotype may be important for predicting response to immune checkpoint inhibitor...

Updated Analysis From KEYNOTE-189: Pembrolizumab or Placebo Plus Pemetrexed and Platinum for Previously Untreated Metastatic Nonsquamous Non-Small-Cell Lung Cancer.

Mar 10, 2020

In KEYNOTE-189, first-line pembrolizumab plus pemetrexed-platinum significantly improved overall survival (OS) and progression-free survival (PFS) compared with placebo plus pemetrexed-platinum in pat...

Prognostic significance of the radiologic features of pneumonitis induced by anti-PD-1 therapy.

Mar 10, 2020

Interstitial lung disease (ILD) induced by anti-programmed-cell death-1 (PD-1) and anti-PD-ligand 1 (PD-L1) is potentially life-threatening and is a common reason of the discontinuation of therapy. In...

Identification of Potential Diagnostic and Prognostic Values of Expression in Lung Cancer, Breast Cancer, and Head and Neck Cancer.

Mar 10, 2020

The aims of this study were to investigate the expression of prolyl 4-hydroxylase subunit alpha-1 (P4HA1) and its relationship with clinicopathological features in lung cancer (LC), breast cancer (BC)...

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