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Surgery General

The prevalence of lower airway anomalies in children with Down syndrome compared to controls.

Mar 24, 2020

Children with Down syndrome (DS) often present with chronic respiratory symptoms. Congenital airway anomalies have been described but data about prevalence is scarce and a comparison to controls is la...

Lipopolysaccharide-Induced Depression-Like Behaviors Is Ameliorated by Sodium Butyrate via Inhibiting Neuroinflammation and Oxido-Nitrosative Stress.

Mar 24, 2020

Depression is a common disease that afflicts one in 6 people. Numerous hypotheses have been raised in the past decades, but the exact mechanism for depression onset remains obscure. Recently, the neur...

Self-Esteem and Non-Medical Use of Prescription Drugs among College Students: Coping as a Mediator.

Mar 24, 2020

Non-medical use of prescription drugs (NMUPD) has become a threat to public health. In the United States, NMUPD is especially common in young adults (aged 18-25). Self-esteem is a robust psychosocial...

Partnering with parents to improve outcomes for substance exposed newborns-a pilot program.

Mar 24, 2020

Assess impact of parental involvement in care provision for term substance exposed newborns (SENs).Prospective observational cohort study included mothers with opioid use disorder and their SENs over ...

On my own terms: Motivations for self-treating opioid-use disorder with non-prescribed buprenorphine.

Mar 24, 2020

The opioid overdose crisis in the United States has prompted an expansion of treatment services, including pharmacotherapy with buprenorphine. However, many people who use illicit opioids (PWUIO) self...

Pharmacological and molecular docking assessment of cryptotanshinone as natural-derived analgesic compound.

Mar 24, 2020

Medicinal plants from traditional chinese medicine are used increasingly worldwide for their benefits to health and quality of life for the relevant clinical symptoms related to pain. Among them, Salv...

Evidence for the alloimmune basis and prognostic significance of Borderline T cell-mediated rejection.

Mar 19, 2020

Prognostic biomarkers of T cell-mediated rejection (TCMR) have not been adequately studied in the modern era. We evaluated 803 renal transplant recipients and correlated HLA-DR/DQ molecular mismatch a...

Pain expectancy, prevalence, severity, and patterns following donor nephrectomy: Findings from the KDOC Study.

Mar 19, 2020

Postoperative pain is an outcome of importance to potential living kidney donors. We prospectively characterized the prevalence, severity and patterns of acute or chronic postoperative pain in 193 LKD...

T cell exhaustion is associated with antigen abundance and promotes transplant acceptance.

Mar 19, 2020

Exhaustion of T cells limits their ability to clear chronic infections or eradicate tumors. Here, in the context of transplantation, we investigated whether T-cell exhaustion occurs and has a role in ...

IgA Nephropathy Recurrence after Kidney Transplantation: Role of Recipient Age and Human Leukocyte Antigen-B Mismatch.

Mar 19, 2020

Recurrence of immunoglobulin (Ig)A nephropathy (rIgAN) is a growing cause of kidney allograft dysfunction. This study was aimed at investigating factors associated with rIgAN and the subsequent progre...

Rational and design of the ROTAS study: a randomized study for the optimal treatment of symptomatic patients with low-gradient severe aortic valve stenosis and preserved left ventricular ejection fraction.

Mar 19, 2020

Fifteen to thirty percentage of patients with severe aortic stenosis (AS) have preserved left ventricular ejection fraction (LVEF) and a discordant AS pattern at Doppler echocardiography, which is cha...

Mid-term outcomes of valve-sparing root reimplantation with leaflet  repair.

Mar 19, 2020

Valve repair for aortic insufficiency (AI) requires a tailored surgical approach determined by the leaflet and aortic disease. In this study, we used a repair-oriented system for the classification of...

Age over 35 years is associated with increased mortality after pulmonary valve replacement in repaired tetralogy of Fallot: results from the UK National Congenital Heart Disease Audit database.

Mar 19, 2020

Many adults with repaired tetralogy of Fallot will require a pulmonary valve replacement (PVR), but there is no consensus on the best timing. In this study, we aim to evaluate the impact of age at PVR...

Five-year follow-up of patients who underwent everolimus-eluting bioresorbable scaffold implantation.

Mar 19, 2020

The aim of this study was to evaluate very long-term results after unrestricted everolimus-eluting bioresorbable scaffolds (BRS) implantation.Previous randomized studies mainly included selected patie...

Effects of Intravenous Tranexamic Acid During Rhytidectomy: A Randomized, Controlled, Double-Blind Pilot Study.

Mar 19, 2020

Tranexamic acid (TXA) is an anti-fibrinolytic agent shown to decrease intraoperative bleeding, reduce transfusions, and improve outcomes across multiple specialties. Within plastic surgery, initial re...

A generative adversarial network approach to predicting postoperative appearance after orbital decompression surgery for thyroid eye disease.

Mar 19, 2020

Orbital decompression for thyroid-associated ophthalmopathy (TAO) is an ophthalmic plastic surgery technique to prevent optic neuropathy and reduce exophthalmos. Because the postoperative appearance c...

Searching for an Alternative Method to Evaluate Surgical Knowledge: Does a Drawing and Labeling Quiz Predict In-Service Exam Performance and Enhance Learning?

Mar 19, 2020

The best methods to assess surgical knowledge are still debated. The authors used a non-multiple-choice test as a pre- and post-conference assessment to measure residents' knowledge gains with compari...

Fournier's gangrene: Five years' experience from a single center in Turkey.

Mar 19, 2020

Is the present study aims to analyze demographic, clinical and surgical data of all patients with FG (Fournier's gangrene) admitted to a tertiary healthcare hospital in the largest city of Turkey.This...

Soft Tissue Contouring at the Time of Osseointegrated Implant Reconstruction for Lower Extremity Amputation.

Mar 19, 2020

Patients with lower extremity amputations using a classic socket prosthesis face many challenges related to the socket-limb interface. The adaptation of osseointegration has allowed for the attachment...

Antibacterial performance of glucose-fructose added MW based zirconia coatings - Possible treatment for bone infection.

Mar 19, 2020

Use of ceramic coatings has increased dramatically in orthopedics by improving their wear resistance and consequent long-term stability. Such stability involves not only the strength of material but a...

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