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Surgery General

In Silico Clinical Trials in the Orthopedic Device Industry: From Fantasy to Reality?

May 13, 2021

The orthopedic device industry relies heavily on clinical evaluation to confirm the safety, performance, and clinical benefits of its implants. Limited sample size often prevents these studies from ca...

Risk Factors of Outcomes of COVID-19 Patients in Korea: Focus on Early Symptoms.

May 13, 2021

Coronavirus disease 2019 (COVID-19) has spread around the globe, and it is important to determine the risk factors of death in the general population. Our study aimed to determine the risk factors of ...

Evaluating the efficacy and safety of ureteral stent placement as a preoperative procedure for gynecological cancer surgeries: A retrospective cohort study.

May 13, 2021

To evaluate the efficacy and safety of ureteral stent placement (USP) as a preoperative procedure for gynecological cancer surgeries.This was a single-institution retrospective cohort study of 259 pat...

Intraoperative hypotension and complications after vascular surgery: A scoping review.

May 13, 2021

Intraoperative hypotension during major surgery is associated with adverse health outcomes. This phenomenon represents a potentially important therapeutic target for vascular surgery patients, who may...

Nintedanib, a multitarget tyrosine kinase inhibitor, suppresses postoperative peritoneal adhesion formation in a rat model.

May 13, 2021

Nintedanib is an antifibrotic agent approved by the United States Food and Drug Administration for the treatment of lung fibrosis. This study aimed to evaluate the efficacy of nintedanib for the preve...

Use of Feedback Data to Reduce Surgical Site Infections and Optimize Antibiotic Use in Surgery: A Systematic Scoping Review.

May 13, 2021

Surgical site infection (SSI) prevention remains significant, particularly in the era of antimicrobial resistance. Feedback on practices and outcomes is known to be key to reduce SSI rates and optimiz...

Development of an international Delphi survey to establish core outcome domains for trials in adults with glomerular disease.

May 10, 2021

Outcomes relevant to treatment decision-making are inconsistently reported in trials involving glomerular disease. Here, we sought to establish a consensus-derived set of critically important outcomes...

Early warning of infection in patients undergoing hematopoietic stem cell transplantation using heart rate variability and serum biomarkers.

May 10, 2021

Early warning of infection is critical to reduce risk of deterioration and mortality, especially in neutropenic patients following hematopoietic stem cell transplantation (HCT). Given that heart rate ...

Assessing multiproxy approaches (Sr/Ca, U/Ca, Li/Mg, and B/Mg) to reconstruct sea surface temperature from coral skeletons throughout the Great Barrier Reef.

May 10, 2021

Due to the increasing concerns of global warming and short instrumental records of sea surface temperature (SST), coral-based proxies, such as δO, Sr/Ca, U/Ca, and Li/Mg have been developed and appli...

Risk of Recall Among Medical Devices Undergoing US Food and Drug Administration 510(k) Clearance and Premarket Approval, 2008-2017.

May 10, 2021

The US Food and Drug Administration (FDA) uses 510(k) clearance and premarket approval (PMA) pathways to ensure device safety before marketing. Premarket approval evaluates high-risk medical devices a...

Effects of COVID-2019 on plastic surgery emergencies in Korea.

May 10, 2021

To fight the coronavirus disease 2019 (COVID-19) pandemic, many countries have implemented social distancing and lockdowns. We investigated the changes in the trauma patterns of emergency plastic surg...

The cosmetic surgery paradox: Toward a contemporary understanding of cosmetic surgery popularisation and attitudes.

May 10, 2021

Modern women feel compelled to meet near-impossible standards of beauty. For many, this pursuit ultimately culminates in cosmetic surgery - a radical form of beautification that is rapidly becoming po...

Knee Flexion-induced Translation of Pullout Sutures Used in the Repair of Medial Meniscus Posterior Root Tears.

May 10, 2021

Medial meniscus posterior root tears (MMPRTs) have recently attracted considerable interest in orthopedics. To date, no in vivo human study has investigated suture translation changes in repaired MMPR...

Clinical validation of the short and long UNESP-Botucatu scales for feline pain assessment.

May 10, 2021

The UNESP-Botucatu multidimensional feline pain assessment scale (UFEPS) is a valid and reliable instrument for acute pain assessment in cats. However, its limitations are that responsiveness was not ...

Giant Intramuscular Myxoma of Thigh- A Rare Case Report.

May 10, 2021

Myxoid soft tissue tumors consist of a heterogeneous group of mesenchymal neoplasms with a hallmark of the abundant extracellular myxoid matrix. Intramuscular myxomas are rare benign tumor affecting t...

Enhancing the cardiovascular protective effects of a healthy dietary pattern with wolfberry (Lycium barbarum): A randomized controlled trial.

May 10, 2021

The consumption of wolfberry (Lycium barbarum), a rich source of carotenoids and bioactive polysaccharides, may serve as a potential dietary strategy for cardiovascular disease (CVD) risk management a...

Previous upper abdominal surgery is a risk factor for nasogastric tube reinsertion after pancreaticoduodenectomy.

May 10, 2021

Pancreaticoduodenectomy without subsequent nasogastric tube management has not been widely adopted due to delayed gastric emptying, the specific and frequent morbidity associated with this surgical pr...

Surgery vs. Functional Bracing for Humeral Shaft Fractures

May 06, 2021

Recent studies have shown that in patients with closed humeral shaft fracture, surgery fails to provide superior functional outcomes when compared with non-operative patients. However, the need for se...

Neoadjuvant Systemic Therapy for Clinically Node-Positive Breast Cancer

May 06, 2021

There is no evaluation of axillary pathologic complete response rates (PCR) for all breast cancer subtypes. This includes patients with and without the pathologically proven node-positive disease. Thi...

Oxygenated End-Hypothermic Machine Perfusion for Kidney Transplant

May 06, 2021

Continuous hypothermic machine perfusion during organ preservation is found to be beneficial on graft function and survival compared with static cold storage (SCS) in kidney transplants. This study ai...

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