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Sleep Disorders

The effect of acute morphine on sleep in male patients suffering from sleep apnea: Is there a genetic effect? An RCT Study.

Dec 17, 2020

Questionnaire-based studies have suggested genetic differences in sleep symptoms in chronic opioid users. The present study aims to investigate if there is a genetic effect on sleep architecture and q...

Polymeric Nanoencapsulation of Zaleplon into PLGA Nanoparticles for Enhanced Pharmacokinetics and Pharmacological Activity.

Dec 17, 2020

Zaleplon (ZP) is a sedative and hypnotic drug used for the treatment of insomnia. Despite its potent anticonvulsant activity, ZP is not commonly used for the treatment of convulsion since ZP is charac...

Greater Severity and Functional Impact of Post-traumatic Headache in Veterans With Comorbid Neck Pain Following Traumatic Brain Injury.

Dec 14, 2020

Post-traumatic headache (PTH) is a commonly experienced symptom after mild traumatic brain injury (mTBI). Blast injury- or blunt injury-related mechanisms for mTBI in veterans can also affect musculos...

Parent-Reported Symptoms and Medications Used Among Children With Severe Neurological Impairment.

Dec 14, 2020

Children with severe neurological impairment (SNI) often take multiple medications to treat problematic symptoms. However, for children who cannot self-report symptoms, no system exists to assess mult...

Occurrence of workplace violence and the psychological consequences of it among nurses working in psychiatric outpatient settings.

Dec 14, 2020

There is a scarcity of studies concerning violence and its consequences in psychiatric outpatient setting. This study aimed to explore the occurrence of workplace violence and the psychological conseq...

Dysregulation of the orexin/hypocretin system is not limited to narcolepsy but has far-reaching implications for neurological disorders.

Dec 10, 2020

Neuropeptides orexin A and B (OX-A/B, also called hypocretin 1 and 2) are released selectively by a population of neurons which projects widely into the entire central nervous system but are localized...

The Bidirectional Association Between Psoriasis & OSA

Dec 08, 2020

With psoriasis and obstructive sleep apnea (OSA) sharing various comorbidities and having a common pathogenesis of inflammatory and immune imbalance, many studies have examined the association between...

Rotigotine: A Review of Analytical Methods for the Raw Material, Pharmaceutical Formulations, and Its Impurities.

Dec 07, 2020

Rotigotine is a dopaminergic agonist developed for the treatment of Parkinson's disease and restless leg syndrome. The pure levorotatory enantiomer is marketed in several countries as a transdermal pa...

The Relationship between Simple Snoring and Sleep Bruxism: A Polysomnographic Study.

Dec 07, 2020

Simple snoring is defined as the production of sound in the upper aerodigestive tract during sleep, not accompanied by other pathologies. Sleep bruxism (SB) refers to repetitive phasic, tonic, or mixe...

Self-Isolation Due to COVID-19 Is Linked to Small One-Year Changes in Depression, Sleepiness, and Insomnia: Results from a Clinic for Sleep Disorders in Shiga Prefecture, Japan.

Dec 07, 2020

We aimed to analyze (a) the changes in depression, sleepiness, insomnia, and sleep habits in relation to the degree of self-isolation and (b) the effects of changes in sleep habits and social interact...

Internal Consistency and Convergent Validity of the Inventory of Hyperacusis Symptoms.

Dec 03, 2020

The aim was to assess the internal consistency and convergent and discriminant validity of a new questionnaire for hyperacusis, the Inventory of Hyperacusis Symptoms (IHS; Greenberg & Carlos 2018)...

Current state of hypnotic use disorders: Results of a survey using the Japanese version of Benzodiazepine Dependence Self-Report Questionnaire.

Dec 03, 2020

Benzodiazepine receptor agonists (BZ-RAs) are frequently prescribed to treat insomnia; however, their long-term use is not recommended. To introduce an appropriate pharmaco-therapy, the current state ...

Treatment of Obstructive Sleep Apnea-Hypopnea Syndrome With a Mandible Advanced Device Increases Nitric Oxide Release and Ameliorates Pulmonary Hypertension in Rabbits.

Dec 03, 2020

To investigate the effects of mandible advanced device (MAD) therapy for obstructive sleep apnea-hypopnea syndrome (OSAHS) on nitric oxide (NO) release and changes in pulmonary artery pressure and str...

Results of coblation midline glossectomy for obstructive sleep apnea.

Nov 30, 2020

The aim of this study is to determine the effectiveness of coblation midline glossectomy for obstructive sleep apnea (OSA) when used as an isolated procedure. We also aim to compare the effect of this...

Hypocretinergic interactions with the serotonergic system regulate REM sleep and cataplexy.

Nov 30, 2020

Loss of muscle tone triggered by emotions is called cataplexy and is the pathognomonic symptom of narcolepsy, which is caused by hypocretin deficiency. Cataplexy is classically considered to be an abn...

Impact of COVID-19 pandemic lockdown on narcolepsy type 1 management.

Nov 30, 2020

Narcolepsy type 1 (NT1) is a chronic rare hypersomnia of central origin requiring a combination of behavioral and pharmacological treatments. During the coronavirus disease 2019 (COVID-19) pandemic, i...

Sleep misestimation among older adults suffering from insomnia with short and normal objective sleep duration and the effects of Cognitive Behaviour Therapy.

Nov 26, 2020

Compare the degree of sleep misestimation in older adults with insomnia presenting with objectively short relative to normal sleep duration, and investigate the differential therapeutic response on sl...

Chronic apnea during REM sleep increases arterial pressure and sympathetic modulation in rats.

Nov 26, 2020

Obstructive sleep apnea can induce hypertension. Apneas in REM may be particularly problematic: they are independently associated with hypertension. We examined the role of sleep stage and awakening o...

Associations of Insomnia Symptoms with Subsequent Health Services Use among Community-Dwelling U.S. Older Adults.

Nov 26, 2020

Determine the association of insomnia symptoms with subsequent health services use, in a representative sample of U.S. older adults.Participants were 4,289 community-dwelling Medicare beneficiaries wh...

Understanding the role of echocardiography in patients with obstructive sleep apnea and right ventricular subclinical myocardial dysfunction - comparison with other conditions affecting RV deformation.

Nov 23, 2020

Despite efforts to treat obstructive sleep apnea syndrome (OSA), the condition remains an important risk factor in the development of cardiovascular disease. Early detection of RV dysfunction with nov...