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Sleep Disorders

Quality of life and its relation with nutritional status in patients with incurable cancer in palliative care.

Feb 10, 2020

Nutritional impairment is common in cancer patients and adversely affects quality of life (QoL). The aim of this study was to investigate the association between nutritional status and QoL in incurabl...

Circulating fibrinogen levels are elevated in patients with obstructive sleep apnea: a systemic review and meta-analysis.

Feb 10, 2020

Fibrinogen is believed to play a role in the pathophysiology of obstructive sleep apnea (OSA) and many studies have assessed circulating fibrinogen concentrations in OSA patients. However, the results...

Polysomnography Findings in Pediatric Spinal Muscular Atrophy Types 1-3

Feb 10, 2020

Sleep disordered breathing (SDB) causes sleep disturbance and daytime symptoms in children with neuromuscular disorders. Although polysomnography (PSG) findings are well described in many neuromuscula...

Successful home respiratory polygraphy to investigate sleep-disordered breathing in children.

Feb 10, 2020

Sleep-disordered breathing (SDB) in children is common. Interest in sleep tests, such as polygraphy (PG), which can be performed in a non-attended setting, are gaining is increasing. PG has, however, ...

Drug-Induced Sleep Endoscopy: Evaluation of a Selection Tool for Treatment Modalities for Obstructive Sleep Apnea.

Feb 10, 2020

Obstructive sleep apnea (OSA) is a very common disorder with important day and nighttime symptoms and long-term effects on health. Different treatment modalities such as positive airway pressure (PAP)...

Increased platelet activation in sleep apnea subjects with intermittent hypoxemia.

Feb 10, 2020

Obstructive sleep apnea (OSA) is independently associated with increased risk for stroke and other cardiovascular diseases. Since activated platelets play an important role in cardiovascular disease, ...

Enhanced production of 5-hydroxytryptophan through the regulation of L-tryptophan biosynthetic pathway.

Feb 04, 2020

5-Hydroxytryptophan (5-HTP) is the precursor of the neurotransmitter serotonin and has been used for the treatment of various diseases such as depression, insomnia, chronic headaches, and binge eating...

Effects of Exercise on Sleep Quality in Pregnant Women:A Systematic Review and Meta-analysis of Randomized Controlled Trials.

Feb 04, 2020

Sleep quality was considered a priority concern facing pregnant women. Conventional wisdom argues that good sleep quality benefits pregnant women and their fetuses. The aim of this study is to assess ...

In-Home Diagnosis of Obstructive Sleep Apnea Using Automatic Video Analysis

Feb 04, 2020

To evaluate the diagnostic accuracy of a non-invasive technology based on image processing for the identification of obstructive sleep apnea (OSA) and its severity at patients' home.Observational, pro...

Immunotherapy in Narcolepsy.

Jan 31, 2020

Narcolepsy type 1 (NT1) is a chronic and disabling sleep disorder due to the loss of hypocretinergic neurons in the lateral hypothalamus pathophysiologically linked to an autoimmune process. Current t...

Pitolisant: A Review in Narcolepsy with or without Cataplexy.

Jan 31, 2020

Pitolisant (Wakix), an orally available, first-in-class antagonist/inverse agonist of the histamine 3 receptor, is approved in the EU (as of March 2016) for the treatment of narcolepsy with or without...

Negative mood as a mediator of the association between insomnia severity and marijuana problems in college students.

Jan 31, 2020

Insomnia symptoms have been linked to problematic marijuana use among young adults, but the mechanism underlying this association and whether sex differences exist, remains unclear. Using cross-sectio...

Development of a Sleep Apnea-Specific Health State Utility Algorithm

Jan 31, 2020

With the increasing emphasis on economic evaluations, there is a need for additional methods of measuring patient utility in the obstructive sleep apnea population.To develop and validate a utility sc...

Driving with undiagnosed obstructive sleep apnea (OSA): High prevalence of OSA risk in drivers who experienced a motor vehicle crash.

Jan 31, 2020

Obstructive sleep apnea (OSA) is a risk factor for motor vehicle crashes (MVC), and patients with diagnosed OSA have a higher likelihood of being involved in a traffic accident. OSA, however, is ofte...

Utility of the sleep stage sequence preceding sleep onset REM periods for the diagnosis of narcolepsy: a study in a Japanese cohort.

Jan 31, 2020

The minimum narcolepsy criteria "mean sleep latency (MSL) ≤8 min and ≥2 sleep onset rapid eye movement (REM) periods (SOREMPs) on polysomnography (PSG) and the multiple sleep latency test (MSLT),...

Sexual disorders and dyspnoea among women with obstructive sleep apnea.

Jan 31, 2020

We aimed to assess sexual function, sexual distress and the prevalence of female sexual dysfunction (FSD) among women with obstructive sleep apnea syndrome (OSA), and to assess if the presence of OSA ...

Symptom Experiences in Colorectal Cancer Survivors After Cancer Treatments: A Systematic Review and Meta-analysis.

Jan 31, 2020

With improved survivorship rates for colorectal cancer (CRC), more CRC survivors are living with long-term disease and treatment side effects. Little research exists on CRC symptoms or symptom managem...

Fear Extinction Memory is Negatively Associated with REM Sleep in Insomnia Disorder.

Jan 30, 2020

Formation and maintenance of fear-extinction memories are disrupted in Post-Traumatic Stress Disorder (PTSD) and anxiety disorders. Sleep contributes to emotional memory consolidation and emotion regu...

Narcolepsy Severity Scale: A reliable tool assessing symptom severity and consequences.

Jan 30, 2020

To define clinically relevant Narcolepsy Severity Scale (NSS) score ranges, confirm its main performances and sensitivity to medications, and determine whether items need to be weighted.143 consecutiv...

Altered surface expression of P2Y receptor with narcolepsy-associated mutations.

Jan 30, 2020

Narcolepsy with cataplexy is a neurological sleep disorder, which is believed to arise from the autoimmune destruction of hypocretin-producing neurons. The purinergic receptor P2Y is associated with n...