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Sleep Disorders

Cannabinoid therapies in the management of sleep disorders: A systematic review of preclinical and clinical studies.

Jul 02, 2020

Cannabinoids, including the two main phytocannabinoids Δ-tetrahydrocannabinol (THC) and cannabidiol (CBD), are being increasingly utilised as pharmacological interventions for sleep disorders. THC an...

The impact of workplace violence on medical-surgical nurses' health outcome: A moderated mediation model of work environment conditions and burnout using secondary data.

Jun 29, 2020

Workplace violence is a prevalent phenomenon in healthcare and nurses are particularly at risk from workplace violence due to the nature of their work or inadequacies within their work environments. A...

IN-HOSPITAL MANAGEMENT OF SLEEP APNEA DURING HEART FAILURE HOSPITALIZATION- A RANDOMIZED CONTROLLED TRIAL.

Jun 29, 2020

Obstructive sleep apnea (OSA) is associated with increased mortality and readmissions in patients with heart failure (HF). The effect of in-hospital diagnosis and treatment of OSA during decompensated...

Neuroendocrine abnormalities associated with untreated first episode patients of major depressive disorder with comorbid obstructive sleep apnea.

Jun 29, 2020

There are few studies that explore the relationship of neuroendocrine hormones of the HPA, HPT and HPG axes with major depressive disorder (MDD) with comorbid obstructive sleep apnea (OSA). The aim of...

Clinical and Epidemiological Characteristics of COVID-19 Patients in Chongqing China.

Jun 25, 2020

To study in-depth the clinical and epidemiological characteristics of pneumonia resulting from COVID-19 and provide evidence for effective public health decisions. This was a retrospective, single-c...

The Effect of Obstructive Sleep Apnea on Absolute Risk of Central Serous Chorioretinopathy.

Jun 25, 2020

To determine the incidence of central serous chorioretinopathy (CSC) stratified by age, sex, and diagnosis with obstructive sleep apnea (OSA), and to determine whether some patients with newly diagnos...

Association between the high risk for obstructive sleep apnea and intracranial carotid artery calcification in patients with acute ischemic stroke.

Jun 22, 2020

Obstructive sleep apnea (OSA) is an independent risk factor for stroke. Furthermore, intracranial carotid artery calcification (ICAC) is a marker for subclinical atherosclerosis and future cardiovascu...

Sleep apnea in men is associated with altered lipid metabolism, glucose tolerance, insulin sensitivity, and body fat percentage.

Jun 22, 2020

Obstructive sleep apnea (OSA) is associated with obesity and risk for type 2 diabetes. In this community-based study, we thoroughly investigated fatty acid metabolism, incretin response, glucose toler...

Influence of Group Resilience on Job Satisfaction Among Korean Nurses: A Cross-Sectional Study.

Jun 22, 2020

This study examined whether the individual and organizational factors of ecological systems theory are associated with job satisfaction among nurses in South Korea.Nursing shortages and high turnover ...

Obstructive sleep apnea, depression and cognitive impairment.

Jun 18, 2020

Obstructive sleep apnea (OSA) is a severe disorder with a high prevalence. Psychiatric comorbidities, especially depressive symptoms and cognitive dysfunction, are often described in OSA patients. Thi...

Motivation and sensitivity to monetary reward in late-life insomnia: moderating role of sex and the inflammatory marker CRP.

Jun 18, 2020

Insomnia is a well-established risk factor for late-life depression, yet the intermediary mechanisms are not known. One plausible mechanism is dysregulation of the reward system, a common feature of d...

Absorption, Distribution, Metabolism, Excretion (ADME), Drug-drug interaction potential and Prediction of Human Pharmacokinetics of SUVN-G3031, a Novel Histamine 3 Receptor (HR) inverse agonist in Clinical development for the treatment of Narcolepsy.

Jun 15, 2020

SUVN-G3031 is a potent and selective inverse agonist of Histmine-3 (H) receptor that is being investigated for the treatment of narcolepsy. SUVN-G3031 has high passive permeability, not a substrate fo...

Continuous positive airway pressure versus mandibular advancement device in the treatment of obstructive sleep apnea: a systematic review and meta-analysis.

Jun 15, 2020

The goal of this study was to review relevant randomized controlled trials in order to determine the efficacy of continuous positive airway pressure (CPAP) versus mandibular advancement device (MAD) i...

A case of Madelung's disease presenting with obstructive sleep apnea.

Jun 11, 2020

Madelung's disease is a rare condition characterized by diffuse, multiple, symmetric, non-encapsulated, fatty accumulation predominantly in neck and upper trunk which can predispose to obstructive sle...

Performance of peripheral arterial tonometry based testing for the diagnosis of obstructive sleep apnea in a large sleep clinic cohort.

Jun 11, 2020

Peripheral arterial tonometry (PAT) based technology represents a validated portable monitoring modality for diagnosis of obstructive sleep apnea (OSA). We assessed the diagnostic accuracy of PAT-base...

Treatment of somatic symptom disorder in childhood: evidence-based psychotherapy interventions

Jun 11, 2020

About 25-30% of patients present themselves in general practice and specialized healthcare with medically unexplained somatic symptoms. The prevalence of these symptoms is the highest among the elderl...

Sleep surgery in syndromic and neurologically impaired children.

Jun 08, 2020

To examine surgery performed for obstructive sleep apnea (OSA) in children with syndromic or neurologic comorbidities.Medical records of 375 children with OSA were retrospectively reviewed, including ...

Everyday and major experiences of racial/ethnic discrimination and sleep health in a multiethnic population of U.S. women: findings from the Sister Study.

Jun 08, 2020

Perceived racial/ethnic discrimination and poor sleep occur across all races/ethnicities in the U.S., although both are most common among racial/ethnic minorities. Few studies have investigated associ...

Effect of treatment on cognitive and attention problems in children with narcolepsy type 1.

Jun 08, 2020

To ascertain the presence of cognitive and attention problems in treatment naïve children with narcolepsy type 1 (NT1) and to explore whether children recently diagnosed with NT1 improve with respect...

Obstructive sleep apnea caused by acromegaly: Case report.

Jun 04, 2020

Acromegaly is an uncommon syndrome caused by growth hormone-producing pituitary adenoma or pituitary gland hypertrophy. Acromegaly is known to be characterized by progressive somatic disfigurement and...