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Sleep Disorders

The importance of specialized sleep investigations in children with a suprasellar tumor.

Jul 23, 2020

Disruption of sleep has great impact on quality of life. In children with a suprasellar tumor and hypothalamic-pituitary dysfunction, the circadian rhythm may be disturbed causing sleep problems. Howe...

A novel cell-free formulation for the treatment of knee osteoarthritis generates better patient-reported health outcomes in more severe cases.

Jul 23, 2020

The bioactive cell-free formulation (BIOF2) for cartilage regeneration has shown a major therapeutic response in severe knee osteoarthritis. However, its effect on patients with mild or moderate stage...

The effectiveness of adjustable oral appliance for older adult patients with obstructive sleep apnea syndrome.

Jul 23, 2020

Oral appliance (OA) treatment for obstructive sleep apnea syndrome (OSAS) has attracted more and more attention due to its low price, comfort, portable and non-invasion. This study aimed to investigat...

Fatal familial insomnia: A new case description with early response to immunotherapy.

Jul 20, 2020

Fatal Familial Insomnia (FFI) is a rare prionopathy with autosomal dominant inheritance. Although it owes its name because insomnia is one of the most frequent and core symptoms, its clinical phenotyp...

The effect of age, gender, income, work, and physical activity on mental health during coronavirus disease (COVID-19) lockdown in Austria.

Jul 20, 2020

The impact of Coronavirus disease (COVID-19) and the governmental restrictions on mental health have been reported for different countries. This study evaluated mental health during COVID-19 lockdown ...

A PERIOD3 variable-number-tandem-repeat polymorphism modulates melatonin treatment response in Delayed Sleep-Wake Phase Disorder.

Jul 20, 2020

We examined whether a polymorphism of the PERIOD3 gene (PER3; rs57875989) modulated the sleep promoting effects of melatonin in Delayed Sleep-Wake Phase Disorder (DSWPD). One hundred and four individu...

Upper Airway Stimulation versus Untreated Comparators in Positive Airway Pressure Treatment Refractory Obstructive Sleep Apnea.

Jul 16, 2020

Understand the impact of insurance coverage on sleep apnea outcomes for patients awaiting upper airway stimulation.Examine the natural history of impact of Upper Airway Stimulation treatment versus in...

Patients with obstructive sleep apnea present with chronic up-regulation of serum HIF-1α protein.

Jul 16, 2020

Obstructive sleep apnea (OSA) is a chronic condition that is characterized by recurrent pauses in breathing during sleep causing intermittent hypoxia. The main factor responsible for oxygen metabolism...

Association between irritability and suicidal ideation in three clinical trials of adults with major depressive disorder.

Jul 16, 2020

Irritability in pediatric samples is associated with higher rates of subsequent suicide-related outcomes. No study, to date, has evaluated the longitudinal association between irritability and suicida...

Automatic positive airway pressure for obstructive sleep apnea in heart failure with reduced ejection fraction.

Jul 13, 2020

Moderate-to-severe obstructive sleep apnea (OSA) is highly prevalent in heart failure patients with reduced left ventricular ejection fraction (HFrEF), and is associated with worsening cardiac functio...

The Psychological Impact of Epidemic and Pandemic Outbreaks on Healthcare Workers: Rapid Review of the Evidence.

Jul 13, 2020

We aim to provide quantitative evidence on the psychological impact of epidemic/pandemic outbreaks (i.e., SARS, MERS, COVID-19, ebola, and influenza A) on healthcare workers (HCWs).Forty-four studies ...

Clinical Characteristics of Cataplectic Attacks in Type 1 Narcolepsy.

Jul 13, 2020

Narcolepsy is a central disorder of hypersomnolence with symptoms of excessive daytime sleepiness, sleep paralysis, and cataplexy. Cataplexy is the sudden loss of muscle tone in either the face, neck,...

Do specific types of sleep disturbances represent risk factors for poorer health-related quality of life in inflammatory bowel disease? A longitudinal cohort study.

Jul 09, 2020

Poor global sleep quality is commonly reported in people with inflammatory bowel disease (IBD) and is linked to poorer health-related quality of life (HRQoL). However, understanding is currently limit...

Performance evaluation of the spectral autocorrelation function and autoregressive models for automated sleep apnea detection using single-lead ECG signal.

Jul 09, 2020

This paper addresses the automated recognition of obstructive sleep apnea (OSA) from the analysis of single-lead ECG signals. This is one of the most important problems that is, critical to the realiz...

Causal relationships between substance use and insomnia.

Jul 09, 2020

Poor sleep quality and insomnia have been associated with the use of tobacco, alcohol, and cannabis, but it is unclear if there is a causal link. In this Mendelian Randomization (MR) study we examine ...

Recent advances in orthognathic surgery.

Jul 06, 2020

The aim of this article is to review the recent literature on orthognathic surgery for treatment of malocclusion and obstructive sleep apnea (OSA). The discussion outlines the refinements of the proce...

Circadian tau differences and rhythm associations in Delayed Sleep-Wake Phase Disorder and sighted Non-24-Hour Sleep-Wake Rhythm Disorder.

Jul 06, 2020

We investigated biological and behavioural rhythm period lengths (i.e., taus) of Delayed Sleep-Wake Phase Disorder (DSWPD) and Non-24-Hour Sleep-Wake Rhythm Disorder (N24SWD). Based on circadian phase...

The influence of placebo administration on the first- night effect in patients with insomnia disorder.

Jul 06, 2020

We aimed to investigate the effects of placebo on the first-night effect (FNE) in insomniacs.In sum, 36 patients with insomnia disorder who met the DSM-5 criteria were enrolled in this study. Sixteen ...

Internet-based cognitive behavioural therapy for depression and anxiety among Arabic-speaking individuals in Sweden: a pilot randomized controlled trial.

Jul 02, 2020

Arabic-speaking immigrants and refugees constitute one of the largest immigrant groups in Sweden. Previous research on Arabic-speaking immigrants indicates elevated levels of psychological disorders, ...

The evolution of the narcolepsy concept in Russia: A historical view.

Jul 02, 2020

Following the first descriptions of narcolepsy with cataplexy by Westphal, Gelineau, and Fischer (1878-1880), Russian authors started to report on "narcolepsy cases" in 1894. It was, however, only in ...