Feb 11, 2021

Tizanidine is an alpha2-adrenergic agonist, used to treat spasticity associated with multiple sclerosis and spinal injury. Tizanidine is primarily metabolized by CYP1A2 and is considered a sensitive i...

Feb 11, 2021

To describe opioid prescribing patterns for patients undergoing kidney cancer surgery and evaluate associations with medical resource utilization in the postoperative setting.Linked Surveillance, Epid...

Feb 11, 2021

To determine the impact of transitioning from opioid to non-opioid analgesia post-vasectomy on unplanned opioid prescriptions and health encounters.A retrospective review for patients who underwent va...

Feb 11, 2021

Pain management and opioid consumption following outpatient orthopedic surgery may be influenced by several variables, including knowledge of safe opioid use. A prospective randomized study was undert...

Feb 11, 2021

The last 40 years of JAMA Psychiatry are reviewed as a celebration of its achievements. The focus of this article is on the evolution of big data as reflected in key journal articles. The review begin...

Feb 11, 2021

Major depressive disorder is a common mental health condition that affects an estimated 16.2 million adults and 3.1 million adolescents in the United States. Yet, a lack of uniformity remains in measu...

Feb 11, 2021

Polygenic risk scores (PRS) are predictors of the genetic susceptibility to diseases, calculated for individuals as weighted counts of thousands of risk variants in which the risk variants and their w...

Feb 11, 2021

Research states that Altered synaptic plasticity is often associated with major depressive disorder (MDD). Disease-associated changes in synaptic functions are tightly correlated with altered microRNA...

Feb 11, 2021

Sleep spindles, defining oscillations of stage 2 non-rapid eye movement sleep (N2), mediate memory consolidation. Schizophrenia is characterized by reduced spindle activity that correlates with impair...

Feb 11, 2021

The study states that In the United States, ~1.4 million individuals identify as transgender. Many transgender adolescents experience gender dysphoria related to incongruence between their gender iden...

Feb 11, 2021

The research states that Rapidly accumulating data from mobile assessments are facilitating our ability to track patterns of emotions, behaviors, biologic rhythms, and their contextual influences in r...

Feb 11, 2021

Chronic alcohol use has important effects on the glutamate system. The metabotropic glutamate 5 receptor has shown promise in preclinical models as a target to reduce drinking-related behaviors and cu...

Feb 10, 2021

Individuals with severe psychiatric disorders have a reduced life expectancy compared to the general population. At the biological level, patients with these disorders present features that suggest th...

Feb 10, 2021

The research states Late-life depression (LLD) is a prevalent and disabling condition in older adults that is often accompanied by slowed processing and gait speed. These symptoms are related to impai...

Feb 10, 2021

The research has been performed as to understand The impulsivity-compulsivity diathesis has been fruitful for examining a range of psychiatric disorders that are commonplace globally, as well as day-t...

Feb 10, 2021

The following analyses have been performed for the cognitive enhancing effects of methylphenidate are well established, but the mechanisms remain unclear. We recently demonstrated that methylphenidate...

Feb 10, 2021

This study was conducted to analyse MIA Induced Dopaminergic Dysfunctions. The research was done by  using animal models suggests that maternal immune activation (MIA) can induce transgenerational ef...

Feb 09, 2021

Training of nonspecialist providers with no formal training in counseling has proven to be an effective strategy to offer more widespread, evidence-based counseling interventions. The objective of thi...

Feb 09, 2021

Osteoarthritis and back pain are one of the leading causes of disabilities. Antidepressants have been used across the world to suppress pain, but their efficacy is not well studied. This study aims to...

Feb 09, 2021

Psychiatric diseases characterized by dysregulated risky decision making are differentially represented in males and females. The factors that govern such sex differences, however, remain poorly under...