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Psychiatry General

Altered cortico-striatal functional connectivity in people with high levels of schizotypy: A longitudinal resting-state study.

Mar 08, 2021

Cortico-striatal functional connectivity has been implicated in the neuropathology of schizophrenia. However, the longitudinal relationship between the cortico-striatal connectivity and schizotypy rem...

Methamphetamine-related postmortem cases in Jeddah, Saudi Arabia.

Mar 08, 2021

A more than 500% increase in the number of deaths involving methamphetamine occurred between 2016 and 2018 in Jeddah, Saudi Arabia. As such, this report employed a validated liquid chromatography tand...

Low-to-Moderate Alcohol Intake Associated with Lower Risk of Incidental Depressive Symptoms: A Pooled Analysis of Three Intercontinental Cohort Studies.

Mar 08, 2021

The existing findings of the longitudinal impact of low-to-moderate drinking on symptomatic depression were controversial, as results ranged from finding no association to finding both a protective an...

Investigations on substituted (2-aminothiazol-5-yl)(imidazo[1,2-a]pyridin-3-yl)methanones for the treatment of Alzheimer's disease.

Mar 08, 2021

Alzheimer's disease (AD) is a neurodegenerative disease majorly affecting old age populations. Various factors that affect the progression of the disease include, amyloid plaque formation, neurofibril...

Activation Syndrome in a Patient With Attention-Deficit/Hyperactivity Disorder Treated With Atomoxetine: A Case Report.

Mar 08, 2021

"Activation syndrome" represents a cluster of symptoms of excessive emotional arousal or behavioral activation, which emerges after the first few weeks of antidepressant treatment or a dose increase a...

Clinical Impact of Psychopathy on Bipolar Disorder.

Mar 08, 2021

. Bipolar disorder (BD) is associated with a significant burden due to affective symptoms and behavioral manifestations, but also cognitive and functional impairment. Comorbidity with other psychiatri...

Circadian rhythms in bipolar disorder patient-derived neurons predict lithium response: preliminary studies.

Mar 08, 2021

Bipolar disorder (BD) is a neuropsychiatric illness defined by recurrent episodes of mania/hypomania, depression and circadian rhythm abnormalities. Lithium is an effective drug for BD, but 30-40% of ...

Prevalence and factors associated with anxiety and depressive symptoms among patients hospitalized with hematological malignancies after chimeric antigen receptor T-cell (CAR-T) therapy: A cross-sectional study.

Mar 08, 2021

We conducted a survey to investigate the prevalence and factors associated with anxiety and depressive symptoms among patients hospitalized with hematological malignancies after chimeric antigen recep...

Magnetic seizure therapy is associated with functional and structural brain changes in MDD: Therapeutic versus side effect correlates.

Mar 08, 2021

Magnetic Seizure therapy (MST) is an effective treatment for major depressive disorder (MDD) but its mechanism of action is not fully understood. The present study sought to characterize neuroimaging ...

Physiological responses to acute psychosocial stress in women with menopausal insomnia.

Mar 04, 2021

Insomnia disorder is a common sleep disorder and frequently emerges in the context of menopause, being associated with menopause-specific factors such as hot flashes and other psychosocial variables. ...

Modularized iCBT‑I self-learn training for university staff-prevention and early intervention in the SARS-CoV-2 crisis: A pilot study.

Mar 04, 2021

Insomnia is a widespread disease in adults and has a high prevalence rate. As sleep disturbances are a risk factor concerning mental and physical health, prevention and early intervention are neces...

Investigating potential associations between neurocognition/social cognition and oxidative stress in schizophrenia.

Mar 04, 2021

Deficits in neurocognition and social cognition play a critical role in the functional impairment of patients with schizophrenia. Increased oxidative stress has been evidenced in schizophrenia. Increa...

Safety of Erector Spinae Plane Blocks in Patients With Chest Wall Trauma on VTE Prophylaxis.

Mar 04, 2021

Current guidelines for severe rib fractures recommend neuraxial blockade in addition to multimodal pain therapies. While the guidelines for venous thromboembolism prevention recommend chemoprophylaxis...

[Diagnostics and Therapy 24/7? Artificial Intelligence as a Challenge and Opportunity in Psychiatry and Psychotherapy].

Mar 04, 2021

The aim of the article is to enable a fundamental understanding of the potentials and requirements of Artificial Intelligence (AI) for psychiatrists in the present and for the development of future wo...

Omega-3 fatty acid in ultra-high-risk psychosis: A systematic review based on functional outcome.

Mar 04, 2021

Among different types of poly unsaturated fatty acids, omega-3 fatty acids (FA) play a substantial role in brain development and functioning. This review was designed to evaluate and synthesize availa...

The effect of N-acetylcysteine on bipolar depression: a systematic review and meta-analysis of randomized controlled trials.

Mar 04, 2021

The current pharmacotherapy of bipolar depression often presents limited efficacy and increased risk for adverse events. N-acetylcysteine (NAC) has been suggested as potentially effective and well-tol...

Associations between the cortisol awakening response and patient-evaluated stress and mood instability in patients with bipolar disorder: an exploratory study.

Mar 04, 2021

The Cortisol Awakening Response (CAR) measured as the transient increase in cortisol levels following morning awakening appears to be a distinct feature of the HPA axis. Patients with bipolar disorder...

Melanopsin-mediated pupillary responses in bipolar disorder-a cross-sectional pupillometric investigation.

Mar 04, 2021

Visible light, predominantly in the blue range, affects mood and circadian rhythm partly by activation of the melanopsin-containing intrinsically photosensitive retinal ganglion cells (ipRGCs). The li...

Storytelling: One arts-based learning strategy to reflect on clinical placement. An integrative review.

Mar 04, 2021

Storytelling is one method of arts-based learning. The pedagogy of arts-based learning integrates the arts into another topic to enhance learning. Nursing students' experiences of clinical placement a...

Impacts on Quality of Life with Escitalopram Monotherapy and Aripiprazole Augmentation in Patients with Major Depressive Disorder: A CAN-BIND Report.

Mar 04, 2021

Many individuals with major depressive disorder (MDD) do not respond to initial antidepressant monotherapy. Adjunctive aripiprazole is recommended for treatment non-response; however, the impacts on q...

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