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Psychiatry General

Polygenic risk for immuno-metabolic markers and specific depressive symptoms: A multi-sample network analysis study.

Apr 05, 2021

About every fourth patient with major depressive disorder (MDD) shows evidence of systemic inflammation. Previous studies have shown inflammation-depression associations of multiple serum inflammatory...

Inflammatory Cytokines, Complement Factor H and Anhedonia in Drug-naïve Major Depressive Disorder.

Apr 05, 2021

Anhedonia is a core symptom of major depressive disorder (MDD) and often associated with poor prognosis. The main objective of the present study was to explore the relationship between complement fact...

Novel Risk Loci and Genetic Risk for Bipolar Disorder

Apr 01, 2021

The genetic relationship of bipolar disorder (BD) in Han Chinese individuals isn't well understood. A recently conducted study discovered several novel risk loci for BD in Han Chinese individuals, but...

Pharmacotherapy and Psychotherapy in Major Depressive Disorder

Apr 01, 2021

In patients with major depressive disorder (MDD), the frequent occurrence of psychiatric comorbidity and residual symptoms were associated with poor long-term outcome. In response, researches introduc...

CYP2C19 and CYP2D6 Metabolizer Status with Antidepressant Exposure

Apr 01, 2021

The precise estimation of the drug metabolism capacity of patients is essential when it comes to the administration of the right personalized dose. This study aims to define the difference in the anti...

Cardiovascular Risk Factors and Cognitive Impairment with Schizophrenia

Apr 01, 2021

Schizophrenia is known to be associated with an increased risk of cognitive dysfunction and cardiovascular risk. However, there's no strong evidence suggesting a clear relationship between these facto...

Effect of Incentives of Alcohol Abstinence

Apr 01, 2021

Several communities have been found to be disproportionately affected by problems with alcohol use. To overcome this problem, they seek appropriate and effective interventions. This study aims to dete...

Age-Specific Prevalence and Incidence of Dementia in Adults with Schizophrenia

Apr 01, 2021

Studies have shown that people with schizophrenia are at a high risk of dementia. However, the magnitude and timing of this association are not known. This study aims to determine the age-specific pre...

Antihypertensive Drug Target Genes with Psychiatric Disorders

Apr 01, 2021

Several observational studies have reported the relationship between antihypertensive medication and psychiatric disorders. The dependence appears to be dependent on the drug class, but no strong evid...

Gabapentin dependence and withdrawal requiring an 18-month taper in a patient with alcohol use disorder: a case report.

Apr 01, 2021

Gabapentin has been widely used to manage post-herpetic neuralgia, peripheral neuropathy, seizure disorders, alcohol use disorder (AUD), alcohol withdrawal, and insomnia. Although usually well tolerat...

Combined Oxytocin and Cognitive Behavioral Social Skills Training for Social Function in People With Schizophrenia.

Apr 01, 2021

A significant proportion of people with schizophrenia are characterized by impaired ability to socially engage with others. The development of effective interventions for social functioning remains a ...

Working memory in schizophrenia: The role of the locus coeruleus and its relation to functional brain networks.

Apr 01, 2021

Evidence suggests functional brain networks, especially the executive control network (ECN) and default mode network (DMN), to be abnormal in schizophrenia. Dysfunctions within the locus coeruleus (LC...

Appropriateness of the post-operative rehabilitation of low energy hip fractures in elderly in comparison with the AAOS appropriate use criteria at a level one trauma center.

Apr 01, 2021

This study aimed to assess the appropriateness of the post-operative rehabilitation of low energy hip fractures in the elderly by comparing between the rehabilitations actually provided at level one t...

A systematic review of metacognitions in Internet Gaming Disorder and problematic Internet, smartphone, and social networking sites use.

Apr 01, 2021

The use of new technologies is growing, and some authors have suggested that frequent use might hide a non-chemical addiction (i.e., technological addiction). Over the last five years several studies ...

inhibits Alzheimer's disease by regulating the complex regulation network with the core of and .

Apr 01, 2021

Current medicine for Alzheimer's disease (AD) cannot effectively reverse or block nerve injury. Traditional Chinese Medicine practice and research imply (Fuzi) may meet this goal.Analysing the anti-A...

Lower Health Literacy of Mania Than Depression Among Older People: A Random Survey of a Community Healthcare Service Center.

Apr 01, 2021

This study examines health literacy among older outpatients in two Community Healthcare Service Centers in Shanghai, China to facilitate the design of public education programs for the aged populatio...

Effects of High- versus Low-Intensity Clinician Training on Implementation of Family-Focused Therapy for Youth with Mood and Psychotic Disorders.

Apr 01, 2021

The implementation of evidence-based psychotherapies often requires significant commitments of time and expense from mental health providers. Psychotherapy protocols with rapid and efficient training ...

Neural function during emotion regulation and future depressive symptoms in youth at risk for affective disorders.

Apr 01, 2021

Affective disorders (AD, including bipolar disorder, BD, and major depressive disorder) are severe recurrent illnesses. Identifying neural markers of processes underlying AD development in at-risk you...

A quantitative method for the selective 5-HT2A agonist 25CN-NBOH in rat plasma and brain.

Apr 01, 2021

In recent years, agonists of the 5-HT receptor have gained increasing attention for their potential therapeutic use to treat psychological disorders such as anxiety and depression. Here, we report the...

Brain reactivity to humorous films is affected by insomnia.

Mar 29, 2021

Emotional reactivity to negative stimuli has been investigated in insomnia, but little is known about emotional reactivity to positive stimuli and its neural representation.We used 3T fMRI to determin...

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