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Psychiatry General

A realist review of medication optimisation of community dwelling service users with serious mental illness.

Dec 11, 2023

Severe mental illness (SMI) incorporates schizophrenia, bipolar disorder, non-organic psychosis, personality disorder or any other severe and enduring mental health illness. Medication, particularly a...

Clinical Assessment Interview for Negative Symptoms (CAINS): A Systematic Review of Measurement Properties.

Nov 13, 2023

Negative symptoms are very important for the overall loss of functioning observed in patients with schizophrenia. There is a need for valid tools to assess these symptoms.We used the COnsensus-based S...

Depression severity mediates stigma and quality of life in clinically stable people with schizophrenia in rural China.

Nov 13, 2023

Depressive symptoms associated with schizophrenia are closely related to stigma and quality of life(QOL). There is, however, no thorough research on the connection between the three. This study sought...

A qualitative study of cultural concepts of distress in northern Haiti.

Nov 13, 2023

Cultural Concepts of Distress (CCDs) are culturally constructed diagnostic categories that exist within a specific society or culture. While several studies have assessed CCDs around the world, few st...

The effect of resilience on bipolar mood during specialty clinic treatment.

Nov 13, 2023

Limitations in mental health resources behoove exploration of factors that may enhance treatment response. One such factor, resilience, has been minimally examined in bipolar disorder.With multi-level...

Neurodevelopmental disorders and cancer networks share pathways, but differ in mechanisms, signaling strength, and outcome.

Nov 06, 2023

Epidemiological studies suggest that individuals with neurodevelopmental disorders (NDDs) are more prone to develop certain types of cancer. Notably, however, the case statistics can be impacted by la...

Neurosyphilis-Induced Folie À Deux: A Case of Prolonged Psychosis.

Nov 06, 2023

Neurosyphilis presentations can include psychiatric symptoms such as psychosis, mania, depression, or changes in personality. Therefore, it can lead to a misdiagnosis with psychiatric disorders. The d...

The effect of augmented reality on preoperative anxiety in children and adolescents: A randomized controlled trial.

Nov 06, 2023

Virtual reality has been shown to be an effective non-pharmacological intervention for reducing anxiety of pediatric patients. A newer immersive technology, that of augmented reality, offers some prac...

PECULIARITIES OF PERCEPTION OF NON-VERBAL STIMULI BY PATIENTS WITH SCHIZOPHRENIA: SUBJECTIVE UNDERSTANDING, INTEREST AND EMOTIONS.

Oct 30, 2023

The aim: The main purpose of this article was to investigate the subjective understanding, interest, and emotional perception of non-verbal stimuli by schizophrenic patients.Materials and methods: For...

Association Between Metabolic Risk Factors and Cognitive Impairment in Schizophrenia Based on Sex.

Oct 30, 2023

Sex differences have been observed in many aspects of schizophrenia, including cognitive deficits. Despite extensive research into the relationship between metabolic factors and cognitive deficits in ...

Addressing self-criticism in depression using CBT-based emotion-focused chairwork: study protocol of a randomised controlled trial.

Oct 30, 2023

Self-criticism is a key feature in people diagnosed with depression, resulting in significant psychological distress. Despite the fact that cognitive-behavioural treatments are readily available, a si...

Plasma Amyloid-β, Total Tau, and Neurofilament Light Chain Across the Alzheimer's Disease Clinical Spectrum: A Population-Based Study.

Oct 30, 2023

Plasma biomarkers have emerged as a promising approach for characterizing pathophysiology in mild cognitive impairment (MCI) and Alzheimer's disease (AD).We aimed to characterize plasma biomarkers for...

Is There an Association Between Parkinson's Disease and Periodontitis? A Systematic Review and Meta-Analysis.

Oct 30, 2023

Multiple observational studies have yielded controversial results regarding the association between Parkinson's disease (PD) and periodontitis.This systematic review and meta-analysis was conducted to...

Health-related quality of life and its determinants during and after treatment for paediatric acute lymphoblastic leukaemia: a national, prospective, longitudinal study in the Netherlands.

Oct 30, 2023

Health-related quality of life (HRQoL) is impaired in paediatric patients with acute lymphoblastic leukaemia (ALL). Over the past decades, ALL treatment has successfully been adjusted to the risk of r...

Risk evaluation of diabetic ketoacidosis associated with antipsychotics among patients with schizophrenia in the Japanese adverse event report database.

Oct 23, 2023

Diabetic ketoacidosis (DKA) is a serious life-threatening condition and can be associated with antipsychotic medication. Asian patients with diabetes exhibit less insulin resistance than Caucasians; h...

Positive association of acetylcholine esterase (AChE) with the neutrophil-to-lymphocyte ratio and HbA1c, and a negative association with hydrogen sulfide (HS) levels among healthy African Americans, and HS-inhibition and high-glucose-upregulation of AChE in cultured THP1 human monocytes.

Oct 23, 2023

The incidence of Alzheimer's disease (AD) is higher in people over the age of 65 and in African Americans (AA). Elevated acetylcholinesterase (AChE) activity has been considered a major player in the ...

Efficacy of vitamins B1 and B6 as an adjunctive therapy to lithium in bipolar-I disorder: A double-blind, randomized, placebo-controlled, clinical trial.

Oct 23, 2023

The use of adjunctive therapy for bipolar disorder is increasingly considered to increase the efficacy of standard treatments. In this randomized clinical trial, we evaluated the effect of vitamins B1...

Metabolic effects of atypical antipsychotics: Molecular targets.

Oct 23, 2023

Atypical antipsychotics (AAPs) are commonly prescribed drugs in the treatment of schizophrenia, bipolar disorder and other mental diseases with psychotic traits. Although the use of AAPs is associated...

The GluN2C/D-specific positive allosteric modulator CIQ rescues delay-induced working memory deficits in mice.

Oct 16, 2023

Working memory is of short duration and is, therefore, particularly sensitive to time delays. Moreover, NMDA receptors are significantly involved in working memory. In the present study, we tested whe...

[Survey on the Current Advertising and Sales of Mucuna Pruriens in Consumer-to-consumer Internet Trading in Japan].

Oct 16, 2023

Mucuna Pruriens (MP) is leguminous plant which contains 5% of levodopa in its seeds. It may have a potential to be used as an alternative therapy for Parkinson's disease (PD). Meanwhile, there is a co...

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