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Psychiatry General

A peripheral antinociceptive effects of a bifunctional μ and δ opioid receptor ligand in rat model of inflammatory bladder pain.

Jul 15, 2021

There is a need to develop a novel analgesic for pain associated with interstitial cystitis/painful bladder syndrome (IC/PBS). The use of the conventional μ-opioid receptor agonists to manage IC/PBS ...

Sex differences in neuroimmune and glial mechanisms of pain.

Jul 15, 2021

Pain is the primary motivation for seeking medical care. Although pain may subside as inflammation resolves or an injury heals, it is increasingly evident that persistency of the pain state can occur ...

Characteristics of Calls to a COVID-19 Mental Health Hotline in the First Wave of the Pandemic in New York.

Jul 12, 2021

This report describes the development, implementation and outcomes of a "COVID-19 Anxiety Hotline," designed to address the community's mental health crisis provoked by the coronavirus pandemic. The s...

A 6-month study on the pattern of emergency department presentations for schizophrenia and other psychotic disorders during COVID-19 lockdown.

Jul 12, 2021

This study investigated the characteristics of patients with schizophrenia and other psychotic disorders presenting to emergency departments (ED) for psychiatric treatment during the first six months ...

Phytochemical analysis and biological activities of "Cherchoomoro" (Nepeta adenophyta Hedge).

Jul 12, 2021

Nepeta adenophyta Hedge (Lamiaceae) is an endemic therapeutic herb from Astore, Gilgit. This plant species has been reported among the local communities, especially for treating abdominal pain, kidney...

Self-harm, suicidal ideation, and the positive symptoms of psychosis: Cross-sectional and prospective data from a national household survey.

Jul 12, 2021

Schizophrenia is associated with premature mortality, partly through increased suicide rates.To examine (1) if persecutory ideas, auditory hallucinations, and probable cases of psychosis are associate...

Efficacy of Cognitive Behavioural Therapy for Bipolar Disorder: a Systematic Review.

Jul 12, 2021

Bipolar disorder (BD) is a serious mental illness with a chronic course and significant morbidity and mortality. BD has a lifetime prevalence rate of 1% to 1.5% and is characterised by recurrent episo...

Socio-demographic and clinical characteristics of patients admitted at the Lunatic Asylum, Bengaluru (now NIMHANS) and treatment outcome in the early 20th century (1903-1911).

Jul 12, 2021

Historiography of South Asian mental asylums is generally skewed towards asylums operated by the British. The Lunatic asylum, Bengaluru, later to become NIMHANS, was one of the early asylums and was a...

Transitional challenges in a two-plus-two nursing program: Phenomenology of student experiences.

Jul 12, 2021

With the concept of self-efficacy as a theoretical framework, this qualitative research study explored the academic, social and psychological challenges faced by students transferring from a community...

Brain volume in chronic ketamine users - relationship to sub-threshold psychotic symptoms and relevance to schizophrenia.

Jul 08, 2021

Ketamine may model aspects of schizophrenia arising through NMDA receptor activity deficits. Although acute ketamine can induce effects resembling both positive and negative psychotic symptoms, chroni...

Stability of schizophrenia diagnosis in a ten-year longitudinal study on first episode of non-affective psychosis: conclusions from the PAFIP cohort.

Jul 08, 2021

To evaluate the ten-year stability of schizophrenia diagnosis in a cohort of first-episode psychosis (FEP) patients and the factors associated with it.Changes in diagnosis of 209 FEP patients were des...

Comorbid alcohol-related problems and suicidality disproportionately impact men and emerging adults among individuals with depressive symptoms.

Jul 08, 2021

Depressive disorders are common among adults with alcohol use disorder and with suicidality; however, demographic differences in comorbid alcohol use disorder, binge drinking, and suicidality are unde...

Association between social network characteristics and prevalent and incident depression: The Maastricht Study.

Jul 08, 2021

Social network characteristics may provide a novel non-pharmaceutical target for the prevention of depression. We investigated the temporal association of a broad range of structural and functional so...

Translational evidence for lithium-induced brain plasticity and neuroprotection in the treatment of neuropsychiatric disorders.

Jul 08, 2021

Increasing evidence indicates lithium (Li) efficacy in neuropsychiatry, pointing to overlapping mechanisms that occur within distinct neuronal populations. In fact, the same pathway depending on which...

Enlightened: addressing circadian and seasonal changes in photoperiod in animal models of bipolar disorder.

Jul 08, 2021

Bipolar disorders (BDs) exhibit high heritability and symptoms typically first occur during late adolescence or early adulthood. Affected individuals may experience alternating bouts of mania/hypomani...

Interactions and implications of Fuzzy-Trace theory for risk taking behaviors in bipolar disorder.

Jul 08, 2021

According to Fuzzy-Trace Theory (FTT), qualitative, bottom-line, "gist" reasoning leads to less risk taking and more mature decision-making, less easily swayed by emotions than quantitative, detail-or...

Facial emotion recognition in major depressive disorder: A meta-analytic review.

Jul 08, 2021

Major depressive disorder (MDD) has been associated with difficulties in social and interpersonal functioning. Deficits in emotion processing may contribute to the development and maintenance of inter...

Inflexibly sustained negative affect and rumination independently link default mode network efficiency to subclinical depressive symptoms.

Jul 08, 2021

Aberrant DMN connectivity and activity have been robustly linked to Major Depressive Disorder (MDD) and risk for depression. This link has mostly been explained in terms of rumination, a form of negat...

Thalamocortical interactions in cognition and disease: the mediodorsal and anterior thalamic nuclei.

Jul 05, 2021

The mediodorsal thalamus (MD) and anterior thalamic nuclei (ATN) are two adjacent brain nodes that support our ability to make decisions, learn, update information, form and retrieve memories, and fin...

Involvement of Vascular Endothelial Growth Factor in schizophrenia.

Jul 05, 2021

Vascular endothelial growth factor (VEGF), which acts as an angiogenic and neurotrophic factor, is involved the regulation of cerebral blood volume and flow in Schizophrenia (SCZ). Several evidence in...

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