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Psychiatry General

A comparison of cognitive performance in the Suffolk County cohort and their unaffected siblings.

Jul 22, 2021

People diagnosed with schizophrenia and other psychoses demonstrate impaired neuropsychological performance. Their unaffected siblings exhibit mild impairments relative to unrelated controls, suggesti...

Altered effective connectivity within an oculomotor control network in individuals with schizophrenia.

Jul 22, 2021

Rapid inhibition or modification of actions is a crucial cognitive ability, which is impaired in persons with schizophrenia (SZP). Primate neurophysiology studies have identified a network of brain re...

Unilateral rhomboid intercostal and subserratus plane block application for analgesia after laparoscopic cholecystectomy surgery :a quasi-experimental study.

Jul 22, 2021

Interfascial plane block applications can be used for postoperative pain after laparoscopic surgery. We aimed to investigate the effect of ultrasound-guided unilateral rhomboid intercostal and subserr...

Effects of transcranial direct current stimulation on experimental pain perception: A systematic review and meta-analysis.

Jul 22, 2021

Many studies have examined the effectiveness of transcranial direct current stimulation (tDCS) on human pain perception in both healthy populations and pain patients. Nevertheless, studies have yielde...

Maternal corticosteroids and depression during gestation and decreased fetal heart rate variability.

Jul 22, 2021

Maternal depression during gestation is an adverse factor in fetal brain development that manifests in later childhood behavioral problems. Fetal heart rate variability (FHRV) mediated by parasympathe...

Behavioral mediators of stress-related mood symptoms in adolescence & young adulthood.

Jul 22, 2021

Stress is a risk factor for unipolar and bipolar mood disorders, but the mechanisms linking stress to specific symptoms remain elusive. Behavioral responses to stress, such as impulsivity and social w...

Assessment of Spaceflight Medical Conditions' and Treatments' Potential Impacts on Behavioral Health and Performance.

Jul 22, 2021

Long-duration space exploration missions will pose significant risks to the physical and behavioral health and performance of the crew. We documented the presence and frequency of (1) behavioral healt...

Multiscale neural modeling of resting-state fMRI reveals executive-limbic malfunction as a core mechanism in major depressive disorder.

Jul 22, 2021

Major depressive disorder (MDD) represents a grand challenge to human health and society, but the underlying pathophysiological mechanisms remain elusive. Previous neuroimaging studies have suggested ...

Beyond Functional Impairment: Redefining Favorable Outcome in Patients with Subarachnoid Hemorrhage.

Jul 22, 2021

For outcome assessment in patients surviving subarachnoid hemorrhage (SAH), the modified Rankin scale (mRS) represents the mostly established outcome tool, whereas other dimensions of outcome such as ...

Validation of PROMIS-29 domain scores among adult burn survivors: A National Institute on Disability, Independent Living, and Rehabilitation Research Burn Model System Study.

Jul 22, 2021

Patient-reported outcomes are important for understanding recovery after burn injury, benchmarking service delivery and measuring the impact of interventions. PROMIS-29 domains have been validated for...

Effect of long working hours and insomnia on depressive symptoms among employees of Chinese internet companies.

Jul 19, 2021

In China, long working hours and insomnia are relatively common among internet company employees. Considering that both can affect mental health, we examined their independent and interaction effects ...

High incidence of acute self-reported sleep disturbances in patients following arthroscopic-assisted knee surgery.

Jul 19, 2021

To evaluate the self-reported incidence of sleep disturbances, defined as ≤7 hours of sleep per 24-hour period, in patients undergoing arthroscopic-assisted knee surgery.Patients who underwent art...

Novel genetic variants associated with brain functional networks in 18,445 adults from the UK Biobank.

Jul 19, 2021

Here, we investigated the genetics of weighted functional brain network graph theory measures from 18,445 participants of the UK Biobank (44-80 years). The eighteen measures studied showed low herita...

Spared performance but increased uncertainty in schizophrenia: Evidence from a probabilistic decision-making task.

Jul 19, 2021

Aberrant attribution of salience to in fact little informative events might explain the emergence of positive symptoms in schizophrenia and has been linked to belief uncertainty. Uncertainty is though...

Transcriptional profile of pyramidal neurons in chronic schizophrenia reveals lamina-specific dysfunction of neuronal immunity.

Jul 19, 2021

While the pathophysiology of schizophrenia has been extensively investigated using homogenized postmortem brain samples, few studies have examined changes in brain samples with techniques that may att...

Dissecting the shared genetic basis of migraine and mental disorders using novel statistical tools.

Jul 19, 2021

Migraine is three times more prevalent in people with bipolar disorder or depression. The relationship between schizophrenia and migraine is less certain although glutamatergic and serotonergic neurot...

Healthcare professionals' experiences of the barriers and facilitators to paediatric pain management in the community at end-of-life: A qualitative interview study.

Jul 19, 2021

Inadequate pain management in community paediatric palliative care is common. Evidence to inform improved pain management in this population is limited.To explore the barriers and facilitators to paed...

Co-exposure of cocaine and cannabinoids and its association with select biological, behavioural and health outcomes: A systematic scoping review of multi-disciplinary studies.

Jul 19, 2021

Cocaine use entails severe health- and social-related harms globally. Treatment options for cocaine dependence are highly limited. Benefits of cannabinoids for addiction have been documented, making i...

Lithium therapy and weight change in people with Bipolar Disorder: a systematic review and meta-analysis.

Jul 19, 2021

Lithium remains the gold standard maintenance treatment for Bipolar Disorder (BD). However, weight gain is a side effect of increasing relevance due to its metabolic implications. We conducted a syste...

Bipolar disorder and Susac syndrome: a case report.

Jul 19, 2021

Susac-syndrome is a rare autoimmune disease that manifests with mood alterations in up to 15% of cases and is usually treated with corticosteroids. We present the case of a 41-year-old woman with a fi...

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