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Psychiatry General

ALARA in Practice - 4 decades of radiological protection at Goesgen NPP.

Aug 05, 2021

This paper provides an overview of results achieved through a whole set of ALARA investigations at the Goesgen Nuclear Power Plant. Doses to workers, the public and the environment have significantly ...

Classic Psychedelic Coadministration with Lithium, but Not Lamotrigine, is Associated with Seizures: An Analysis of Online Psychedelic Experience Reports.

Aug 05, 2021

Psychedelics show promise in treating unipolar depression, though patients with bipolar disorder have been excluded from recent psychedelic trials. There is limited information on the use of classic p...

A technology of a different sort: microraft arrays.

Aug 05, 2021

A common procedure performed throughout biomedical research is the selection and isolation of biological entities such as organelles, cells and organoids from a mixed population. In this review, we de...

Influence of sample preparation optimization on the accuracy of dose assessment of an automatic non-fluorescent MN scoring system.

Aug 05, 2021

Automatizing the scoring of the cytokinesis-blocked micronucleus assay spares a lot of valuable time. The dose-effect relationship can be applied reliably for dose estimation, if the quality of the s...

Development of potent and effective synthetic SARS-CoV-2 neutralizing nanobodies.

Aug 05, 2021

The respiratory virus responsible for coronavirus disease 2019 (COVID-19), severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has affected nearly every aspect of life worldwide, claiming th...

Network Changes & Cognitive Impairment in MS

Aug 04, 2021

“Cognitive impairment in patients with multiple sclerosis (MS) is related to functional network changes, based on previous cross-sectional research,” explains Marijn Huiskamp, MSc. “My colleague...

Patient reported outcomes after minimally invasive retroperitoneal pancreatic necrosectomy to treat acute pancreatitis - an exploratory study.

Aug 02, 2021

A minimally invasive retroperitoneal pancreatic necrosectomy (MIRPN) decreases morbidity and mortality from necrotizing acute pancreatitis. However, the impact of MIRPN on patient reported outcomes (P...

Enhancing stress reactivity and wellbeing in early schizophrenia: A randomized controlled trial of Integrated Coping Awareness Therapy (I-CAT).

Aug 02, 2021

Individuals with schizophrenia spectrum disorders (SSD) are at heightened risk for exposure to stressful life events which can lead to increased sensitivity to stress and a dysregulated stress respons...

Excessive and pathological Internet use - Risk-behavior or psychopathology?

Aug 02, 2021

Pathological Internet use (but only with respect to gaming) is classified as mental disorder in the ICD-11. However, there is a large group of adolescents showing excessive Internet use, which may rat...

Changes of neurocognitive status in patients with the first-episode psychosis after 18 months of treatment-A prospective cohort study.

Aug 02, 2021

Neurocognitive symptoms exert the most influence on treatment outcomes over the course of schizophrenia, starting from the first-episode of psychosis (FEP) onwards. Our aim was to analyze the neurocog...

Quantified language connectedness in schizophrenia-spectrum disorders.

Aug 02, 2021

Language abnormalities are a core symptom of schizophrenia-spectrum disorders and could serve as a potential diagnostic marker. Natural language processing enables quantification of language connected...

Impact of the COVID-19 pandemic on acute inpatient psychiatric units in Spain.

Aug 02, 2021

Patients with more severe mental health symptoms are treated in acute inpatient psychiatric units (AIPUs), but the functioning of these units throughout Spain has been challenged by the COVID-19 pande...

Neuronal cells from bipolar individuals are more susceptible to glutamate induced apoptosis than cells from non-bipolar subjects.

Aug 02, 2021

Bipolar disorder (BD) is associated with marked parenchymal brain loss in a significant fraction of patients. The lack of necrosis in postmortem examination suggests an apoptotic process. Emerging evi...

Clinical evidence that a dysregulated master neural network modulator may aid in diagnosing schizophrenia.

Aug 02, 2021

There are no validated biomarkers for schizophrenia (SCZ), a disorder linked to neural network dysfunction. We demonstrate that collapsin response mediator protein-2 (CRMP2), a master regulator of cyt...

Peripheral Levels of C-reactive protein, tumor necrosis factor-α, interleukin-6, and interleukin-1β across the mood spectrum in bipolar disorder: a meta-analysis of mean differences and variability.

Aug 02, 2021

It is unclear whether differences exist in the magnitude and variability of pro-inflammatory mediators in the different phases of bipolar disorder (BD) and among subjects with BD, as compared to healt...

Stress management versus cognitive restructuring in trauma-affected refugees - A follow-up study on a pragmatic randomised trial.

Aug 02, 2021

There is a lack of research and consensus with respect to long-term effective treatments for trauma-affected refugees. The purpose of this follow-up study of a randomised clinical trial was to investi...

Chronotype in individuals with schizophrenia: A meta-analysis.

Aug 02, 2021

Emerging evidence shows that evening chronotype is associated with mental health problems, especially mood disorders, but few studies have investigated its association with schizophrenia. Based on met...

A systematic review of suicide and suicide attempts in adolescents with psychotic disorders.

Aug 02, 2021

Suicide is the main cause of premature death in patients with psychosis. Therefore, the goal of the present study was to review suicide in adolescents with psychotic disorders by evaluating factors as...

Sleeping through a pandemic: impact of COVID-19 related restrictions on narcolepsy and idiopathic hypersomnia.

Jul 29, 2021

To assess the impact of COVID-19 related restrictions on narcolepsy type 1 (NT2), narcolepsy type 2 (NT2), and idiopathic hypersomnia (IH).Participants with NT1, NT2 and IH followed in a university ho...

Antipsychotics Effects on Network-Level Reconfiguration of Cortical Morphometry in First-Episode Schizophrenia.

Jul 29, 2021

Cortical thickness reductions are evident in schizophrenia (SZ). Associations between antipsychotic medications (APMs) and cortical morphometry have been explored in SZ patients. This raises the quest...

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