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Psychiatry General

High stability of EEG spectral power across polysomnography and multiple sleep latency tests in good sleepers and chronic insomniacs.

Feb 19, 2024

To assess the stability of electroencephalographic (EEG) spectral features across overnight polysomnography (PSG) and daytime multiple sleep latency tests (MSLTs) in chronic insomniacs (CIs) and norma...

Depressive inclinations mediate the association between personality (neuroticism/conscientiousness) and TikTok Use Disorder tendencies.

Feb 19, 2024

We introduce a novel measure for assessing TikTok overuse, called the TikTok Use Disorder-Questionnaire (TTUD-Q). As part of ongoing investigations into the suitability of the World Health Organizatio...

Targeting an inflammation-amplifying cell population can attenuate osteoarthritis-associated pain.

Feb 19, 2024

Understanding of pain in osteoarthritis, its genesis, and perception is still in its early stages. Identification of precise ligand-receptor pairs that transduce pain and the cells and tissues in whic...

Pharmacogenomic overlap between antidepressant treatment response in major depression & antidepressant associated treatment emergent mania in bipolar disorder.

Feb 19, 2024

There is increasing interest in individualizing treatment selection for more than 25 regulatory approved treatments for major depressive disorder (MDD). Despite an inconclusive efficacy evidence base,...

Corticosteroids and mania: a systematic review.

Feb 19, 2024

Corticosteroids are widely prescribed for a variety of medical conditions. Accumulating evidence suggests that their use may be associated with adverse psychiatric effects, including mania. In this s...

Exploring mental health approaches and curriculum in physiotherapy: an Australasian perspective.

Feb 19, 2024

Exposure to mental health problems are becoming increasingly more frequent within physiotherapy. Physiotherapists recognize the need for a biopsychosocial approach, however their knowledge, assessment...

Psychiatric Polygenic Risk Scores Across Youth With Bipolar Disorder, Youth at High Risk for Bipolar Disorder, and Controls.

Feb 12, 2024

There is a pronounced gap in knowledge regarding the polygenic underpinnings of youth bipolar disorder (BD). This study aimed to compare polygenic risk score (PRS) in youth with BD, youth at high clin...

Association study of the complement component C4 gene and suicide risk in schizophrenia.

Feb 12, 2024

Schizophrenia is a severe mental illness and a major risk factor for suicide, with approximately 50% of schizophrenia patients attempting and 10% dying from suicide. Although genetic components play a...

Involvement of the Na, K-ATPase α1 Isoform and Endogenous Cardiac Steroids in Depression- and Manic-like Behaviors.

Feb 12, 2024

Bipolar disorder (BD) is a severe and common chronic mental illness characterized by recurrent mood swings between depression and mania. The biological basis of the disease is poorly understood, and i...

Chronic Treatment with Oil Exerts Antimanic Properties and Reduces Brain Inflammation in Rats.

Feb 12, 2024

(NS) is a native herb consumed habitually in several countries worldwide, possessing manifold therapeutic properties. Among them, anti-inflammatory features have been reported, presumably relating to...

Metabolic acidemia due to saline absorption during transurethral and transcervical surgery: a report of 2 cases.

Feb 12, 2024

The development of endoscopic systems that include bipolar electrocautery has enabled the use of normal saline irrigation in transurethral or transcervical endoscopic surgery. However, excessive salin...

The Mental Health of Elite-Level Coaches: A Systematic Scoping Review.

Feb 12, 2024

Elite-level coaches are exposed to multiple performance, organisational and personal stressors which may contribute to reduced mental health and wellbeing. This systematic scoping review examined the ...

Descriptors of water aggregation.

Feb 12, 2024

We rely on a total of 23 (cluster size, 8 structural, and 14 connectivity) descriptors to investigate structural patterns and connectivity motifs associated with water cluster aggregation. In addition...

The neutrophil-to-Lymphocyte ratio is associated with clinical symptoms in first-episode medication-naïve patients with schizophrenia.

Feb 05, 2024

Innate immunity has been shown to be associated with schizophrenia (Sch). This study explored the relationship between symptoms and neutrophil-to-lymphocyte ratio (NLR) (a marker of innate immunity) i...

Neural markers of mania that distinguish inpatient adolescents with bipolar disorder from those with other psychopathology.

Feb 05, 2024

Pediatric bipolar disorder (BD) is difficult to distinguish from other psychiatric disorders, a challenge which can result in delayed or incorrect interventions. Using neuroimaging we aimed to identif...

A comparison of recurrence rates after discontinuation of second-generation antipsychotic long-acting injectable versus corresponding oral antipsychotic in the maintenance treatment of bipolar disorder: A systematic review.

Feb 05, 2024

It has been previously reported that among patients with schizophrenia that long-acting injectable (LAI) antipsychotic formulations can delay time to relapse longer when compared to their oral equival...

Associations of chronotype with anxiety, depression and insomnia among general adult population: A cross-sectional study in Hubei, China.

Jan 29, 2024

The relationship between chronotype and anxiety, depression, and insomnia was inconsistent. We aimed to assess the association between chronotype and mental health and the potential moderating effect ...

Ultra-high risk for psychosis stigma: an updated Systematic Review.

Jan 29, 2024

To clarify if stigma associated with schizophrenia has also been directed towards the ultra-high risk for psychosis (UHR) population, the present review aimed at synthetizing the existing literature t...

Exploring depression in people with schizophrenia spectrum disorders: A cross-sectional analysis of the clinical relationship with Positive and Negative Syndrome Scale dimensions.

Jan 29, 2024

Evidence on the relationship of depression with clinical dimensions of schizophrenia remains limited. This cross-sectional study aimed at exploring the association of depression with the Positive and ...

Chronic exposure to imipramine induces a switch from depression-like to mania-like behavior in female serotonin transporter knockout rats: Role of BDNF signaling in the infralimbic cortex.

Jan 29, 2024

Bipolar disorder (BD) is a highly burdensome psychiatric disorder characterized by alternating states of mania and depression. A major challenge in the clinic is the switch from depression to mania, w...

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