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Psychiatry General

A Reduced Tryptophan Diet in Patients with Diarrhoea-Predominant Irritable Bowel Syndrome Improves Their Abdominal Symptoms and Their Quality of Life through Reduction of Serotonin Levels and Its Urinary Metabolites.

Dec 12, 2022

(1). An essential component of any treatment for patients with irritable bowel syndrome (IBS) is an adequate diet. Currently, a low FODMAP diet is recommended as a first-line therapy, but it does not ...

Fall Risk, Sleep Behavior, and Sleep-Related Movement Disorders in Young Urbanites Exposed to Air Pollution.

Dec 12, 2022

Quadruple aberrant hyperphosphorylated tau, amyloid-β, α-synuclein, and TDP-43 pathology had been documented in 202/203 forensic autopsies in Metropolitan Mexico City ≤40-year-olds with high expos...

The Role of D-Serine and D-Aspartate in the Pathogenesis and Therapy of Treatment-Resistant Schizophrenia.

Dec 12, 2022

Schizophrenia (Sch) is a severe and widespread mental disorder. Antipsychotics (APs) of the first and new generations as the first-line treatment of Sch are not effective in about a third of cases and...

Transcriptomics and metabolomics together reveal the underlying mechanism of heroin hepatotoxicity.

Dec 12, 2022

Researches on heroin are more about addiction and some infectious diseases it causes, but liver fibrosis caused by heroin abuse and the mechanism of heroin hepatotoxicity in addicts are ignored. To ex...

The effects of pregnancy-related Medicaid expansions on maternal, infant, and child health.

Dec 12, 2022

Prior research has examined how late 1980s pregnancy-related Medicaid eligibility expansions influenced outcomes around the time of birth and, more recently, adult outcomes. We offer a close examinati...

ZBTB20-AS1 promoted Alzheimer's disease progression through ZBTB20/GSK-3β/Tau pathway.

Dec 12, 2022

To elucidate the potential molecular mechanisms of ZBTB20-AS1 on ZBTB20 and GSK-3β/Tau signaling pathway in the pathogenesis of Alzheimer's disease (AD), SH-SY5Y cells were obtained for in vitro exp...

Altered patterns of central executive, default mode and salience network activity and connectivity are associated with current and future depression risk in two independent young adult samples.

Dec 12, 2022

Neural markers of pathophysiological processes underlying the dimension of subsyndromal-syndromal-level depression severity can provide objective, biologically informed targets for novel interventions...

Karl Grassmann's 1896 paper "critical overview of contemporary theories of the heredity of the psychoses".

Dec 12, 2022

Four years before the rediscovery of Mendel's work in 1900, Karl Grassmann published a detailed, scholarly review of the heredity of psychosis which we here review. A full translation is in the append...

PRESTO 2: An International Survey to Evaluate Patients' Injection Experiences with the Latest Devices/Formulations of Long-Acting Somatostatin Analog Therapies for Neuroendocrine Tumors or Acromegaly.

Dec 12, 2022

Real-world data evaluating patients' injection experiences using the latest devices/formulations of the long-acting (LA) somatostatin analogs (SSAs) lanreotide Autogel/Depot (LAN; Somatuline®) and oc...

Methods to assess adults' learning styles and factors affecting learning in health education: A scoping review.

Dec 12, 2022

To develop learner-centered education, knowledge about learning styles and factors that affect the ability to learn in patients and their significant others are essential. The present scoping review a...

A Systematic Review for Searching Biomarkers to Guide Interventions in ASD

Dec 09, 2022

A study was conducted to evaluate and catalog response biomarkers linked to autism spectrum disorder (ASD) symptoms. The goal of the study was to help improve clinical trials. In April 2020, a meth...

Legalization and Reform of Psychedelic Drugs in the US

Dec 09, 2022

A patchwork of state law changes has made psychedelic substances more widely available in the US. Consensus on treatment models, training and direction for healthcare professionals, and preparation fo...

Risk of Congenital Malformations and In-utero Antipsychotic Drug Exposure in Nordic and American Populations

Dec 09, 2022

Psychiatric problems are quite common and have been related to detrimental effects on maternal functioning, conception, and healthy infant development. Despite the fact that the use of antipsychotic m...

Thirty years of research on negative symptoms of schizophrenia: A scientometric analysis of hotspots, bursts, and research trends.

Dec 05, 2022

Research on negative symptoms of schizophrenia has received renewed interest since the 1980s. A scientometric analysis that objectively maps scientific knowledge, with changes in recent trends, is cur...

Thirty years of research on negative symptoms of schizophrenia: A scientometric analysis of hotspots, bursts, and research trends.

Dec 05, 2022

Research on negative symptoms of schizophrenia has received renewed interest since the 1980s. A scientometric analysis that objectively maps scientific knowledge, with changes in recent trends, is cur...

Exploring the sociodemographic, clinical and neuropsychological factors associated with relational memory in schizophrenia.

Dec 05, 2022

The Transverse Patterning (TP) task has been used to measure episodic relational memory (RM) deficits in clinical populations. Individuals with schizophrenia often fail to learn TP with standard, and ...

Development, evaluation and adaptation of a critical realism informed theory of procedural pain management in preterm infants: The PAIN-Neo theory.

Dec 05, 2022

To present the development, evaluation and adaptation of the PAIN-Neo theory.Theory development.A review of literature was conduct from 1980 to 2021.Using a critical realism paradigm, this paper prese...

Prelimbic and infralimbic medial prefrontal cortex neuron activity signals cocaine seeking variables across multiple timescales.

Dec 05, 2022

The prefrontal cortex is critical for execution and inhibition of reward seeking. Neural manipulation of rodent medial prefrontal cortex (mPFC) subregions differentially impacts execution and inhibiti...

The impact of outcome expectancy on therapy outcome in adolescents with borderline personality disorder.

Dec 05, 2022

Outcome expectancy has been found to be a significant predictor of psychotherapy outcome. However, given that severity, chronicity and comorbidity are moderators of outcome expectancy, it is important...

Multiparametric Quantitative Imaging Biomarker as a Multivariate Descriptor of Health: A Roadmap.

Dec 05, 2022

Multiparametric quantitative imaging biomarkers (QIBs) offer distinct advantages over single, univariate descriptors because they provide a more complete measure of complex, multidimensional biologica...

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