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Psychiatry General

ASC specks exacerbate α‑synuclein pathology via amplifying NLRP3 inflammasome activities.

Feb 06, 2023

Inflammasome activation has a pathogenic role in Parkinson's disease (PD). Up-regulated expressions of inflammasome adaptor apoptosis-associated speck-like protein containing a CARD (ASC) and assembly...

Targeting galectin-3 to counteract spike-phase uncoupling of fast-spiking interneurons to gamma oscillations in Alzheimer's disease.

Feb 06, 2023

Alzheimer's disease (AD) is a progressive multifaceted neurodegenerative disorder for which no disease-modifying treatment exists. Neuroinflammation is central to the pathology progression, with evide...

One test to rule them all: A qualitative study of formal, informal, and hidden curricula as drivers of USMLE "exam mania".

Feb 06, 2023

High-stakes examinations are an integral part of medical education. To practice in the United States (U.S.), students must pass the U.S. Medical Licensing Examinations (USMLE). With the transition of ...

A systematic review on the effectiveness of dialectical behavior therapy for improving mood symptoms in bipolar disorders.

Feb 06, 2023

Evidence-based psychotherapies available to treat patients with bipolar disorders (BD) are limited. Dialectical behavior therapy (DBT) may target several common symptoms of BD. We conducted a systemat...

False-positive incidental lesions detected on contrast-enhanced breast MRI: clinical and imaging features.

Feb 06, 2023

To identify demographic and imaging features of MRI-detected enhancing lesions without clinical, ultrasound, and mammographic correlation associated with false-positive outcomes, impacting patient car...

Non-conscious processing of fear faces: a function of the implicit self-concept of anxiety.

Feb 06, 2023

Trait anxiety refers to a stable tendency to experience fears and worries across many situations. High trait anxiety is a vulnerability factor for the development of psychopathologies. Self-reported t...

Left insular cortical thinning differentiates the inattentive and combined subtype of adult attention-deficit/hyperactivity disorder.

Feb 06, 2023

Neuroimaging studies in attention-deficit/hyperactivity disorder (ADHD) demonstrated decreased global gray matter volume. In terms of surface parameters, most investigations focused on cortical thickn...

Multi-generation exposure to polystyrene nanoplastics showed no major adverse effects in Daphnia magna.

Feb 06, 2023

Long-term impacts of plastics exposure to organisms, especially to the smallest plastics fraction, nanoplastics (NPs; ≤1 μm), are yet to be fully understood. The data concerning multiple generati...

Risk of Severe COVID-19 Infection and Other SARIs in Preexisting Neuropsychiatric Conditions

Feb 03, 2023

The following is a summary of "Preexisting Neuropsychiatric Conditions and Associated Risk of Severe COVID-19 Infection and Other Acute Respiratory Infections," published in the November 2022 issue of...

Improving Suicide Risk Screening to Help Identify Patients at Highest Risk

Feb 02, 2023

“Suicide risk screening in primary care results in very high false positive rates, according to previous research,” explains Craig J. Bryan, PsyD, ABPP. “More than 95% of patients who screen pos...

CSC First-Episode Psychosis: Prediction Tool for Individual Outcome Trajectories

Feb 02, 2023

The following is a summary of "Prediction Tool for Individual Outcome Trajectories Across the Next Year in First-Episode Psychosis in Coordinated Specialty Care," published in the November 2022 issue ...

Hospitalization and Death Rates Associated with Pharmacological Treatments for Amphetamine Use Disorders

Feb 01, 2023

The following is a summary of "Association of Pharmacological Treatments and Hospitalization and Death in Individuals With Amphetamine Use Disorders in a Swedish Nationwide Cohort of 13965 Patients," ...

Collaborative Child Mental Health Care Program: Effect of General Practitioner Training

Jan 31, 2023

The following is a summary of "Effect of General Practitioner Training in a Collaborative Child Mental Health Care Program on Children’s Mental Health Outcomes in a Low-Resource Setting," published ...

Escitalopram Vs. MBSR for the Treatment of Adult Anxiety Disorders

Jan 30, 2023

The following is a summary of "Mindfulness-Based Stress Reduction vs. Escitalopram for the Treatment of Adults With Anxiety Disorders," published in the November 2022 issue of Psychiatry by Hoge, et a...

Facial expression-based indicators of schizophrenia: Evidence from recent research.

Jan 30, 2023

Impaired ability to recognize emotion in other's face (decoding) or to express emotion through the face (encoding) are considered critical in schizophrenia. The topic of research draws considerable at...

Augmenting DSM-5 diagnostic criteria with self-attention-based BiLSTM models for psychiatric diagnosis.

Jan 30, 2023

Most previous studies make psychiatric diagnoses based on diagnostic terms. In this study we sought to augment Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5) diagnostic cri...

m A mRNA methylation in human brain is disrupted in Lewy body disorders.

Jan 30, 2023

N6-methyladenosine modification of RNA (m A) regulates translational control which may influence neuronal dysfunction underlying neurodegenerative diseases. Using microscopy and a machine learning app...

Korean Medication Algorithm Project for Bipolar Disorder 2022: Comparisons with Other Treatment Guidelines.

Jan 30, 2023

The objective of this study was to compare recommendations of the Korean Medication Algorithm Project for Bipolar Disorder 2022 (KMAP-BP 2022) with other recently published guidelines for treating bip...

Psychometric Properties of the Korean Version of Functioning Assessment Short Test in Bipolar Disorder.

Jan 30, 2023

The Functioning Assessment Short Test (FAST) is a relatively specific test for bipolar disorders designed to assess the main functioning problems experienced by patients. This brief instrument include...

The Weaving Healthy Families program: Promoting parenting practices, family resilience, and communal mastery.

Jan 30, 2023

Parenting quality, family resilience, and community resilience and support have been found to be primary protective factors for the disproportionate burden of anxiety, posttraumatic stress disorder (P...

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