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Psychiatry General

Evaluating global brain connectivity as an imaging marker for depression: influence of preprocessing strategies and placebo-controlled ketamine treatment.

Jan 30, 2020

Major depressive disorder (MDD) is associated with altered global brain connectivity (GBC), as assessed via resting-state functional magnetic resonance imaging (rsfMRI). Previous studies found that an...

Integrating Motivational Interviewing in Pain Neuroscience Education for People With Chronic Pain: A Practical Guide for Clinicians.

Jan 30, 2020

Pain neuroscience education (PNE) and motivational interviewing (MI) have been widely implemented and tested in the field of chronic pain management, and both strategies have been shown to be effectiv...

Skin Infections and Outpatient Burn Management: Outpatient Burn Management.

Jan 30, 2020

Burns, whether caused by thermal, chemical, or electrical exposure, are common and often preventable. Burn injuries are most common in children. All patients with burns should undergo primary and seco...

A Narrative Pharmacological Review of Buprenorphine: A Unique Opioid for the Treatment of Chronic Pain.

Jan 30, 2020

Buprenorphine is a Schedule III opioid analgesic with unique pharmacodynamic and pharmacokinetic properties that may be preferable to those of Schedule II full μ-opioid receptor agonists. The structu...

Anti-inflammatory and metabolic reprogramming effects of MENK produce antitumor response in CT26 tumor-bearing mice.

Jan 30, 2020

Methionine enkephalin (MENK), an endogenous opioid peptide, has a role in nervous system, immune system, and anticancer therapy. Inflammation, metabolism and cancer are closely intertwined with each o...

The identification of risk factors contributing to accidental opioid poisonings in companion dogs using data from a North American poison control center (2006-2014).

Jan 30, 2020

In the last decade, there has been a marked increase in opioid-related human deaths in the U.S. However, the effects of the growth in opioid use on vulnerable populations, such as pet dogs, are largel...

Neovascular age-related macular degeneration and its association with Alzheimer's disease.

Jan 30, 2020

In developed countries, people of advanced age go permanently blind most often due to age-related macular degeneration, while at global level, this disease is the third major cause of blindness, after...

Negative Evidence for a Role of APH1B T27I Variant in Alzheimer's Disease.

Jan 30, 2020

γ-secretase is a macromolecular complex that catalyzes intramembranous hydrolysis of over 100 membrane-bound substrates. The complex is composed of presenilin (PS1 or PS2), anterior pharynx defect-1(...

Prediction of Freezing of Gait in Patients with Parkinson's Disease by Identifying Impaired Gait Patterns.

Jan 30, 2020

Freezing of gait (FoG) prediction, combined with rhythmic laser cues, may help Parkinson's disease (PD) patients overcome FoG episodes. This study aimed to utilize the impaired gait patterns preceding...

Impact of posttranslational modifications on atomistic structure of fibrinogen.

Jan 30, 2020

Oxidative stress in humans is related to various pathophysiological processes, which can manifest in numerous diseases including cancer, cardiovascular diseases, and Alzheimer's disease. On the atomis...

A survey on machine and statistical learning for longitudinal analysis of neuroimaging data in Alzheimer's disease.

Jan 30, 2020

Recently, longitudinal studies of Alzheimer's disease have gathered a substantial amount of neuroimaging data. New methods are needed to successfully leverage and distill meaningful information on the...

Mental health literacy of ADHD, autism, schizophrenia, and bipolar disorder: a cross-cultural investigation.

Jan 30, 2020

Mental health literacy (MHL) is linked to help-seeking behaviours. Although lay people are not always well aware of mental health conditions, few international campaigns and interventions have been d...

Carrier-Induced Hyporesponsiveness to Pneumococcal Conjugate Vaccines: The Influence of Serotypes, Timing, and Previous Vaccine Dose Unraveled.

Jan 30, 2020

Pneumococcal conjugate vaccines (PCVs) elicit lower immune response against serotypes carried before or at the time of vaccination (hyporesponsiveness) in infants. The limited studies conducted to dat...

Neonatal red blood cell transfusion practices in Switzerland: national survey and review of international recommendations.

Jan 30, 2020

WHAT IS KNOWN ON THE SUBJECT? Red blood cell transfusions are frequently used in the care of newborns, particularly premature infants. Some countries have guidelines regarding preparation, indication ...

Highly Sensitive and Contactless Ammonia Detection Based on Nanocomposites of Phosphate Functionalized Reduced Graphene Oxide/Polyaniline Immobilized on Microstrip Resonators.

Jan 30, 2020

Ammonia is a key-compound in a variety of industrial sectors, including automotive, chemical and food. Its hazardous effects on the environment and human health require the implementation of proper sa...

Association between Adult Attention Deficit/Hyperactivity Disorder and Intravenous Misuse of Opioid and Benzodiazepine in Patients under Opioid Maintenance Treatment: A Cross-Sectional Multicentre Study.

Jan 30, 2020

Intravenous misuse and attention-deficit/hyperactivity disorder (ADHD) are common in patients under opioid maintenance treatment (OMT), who often misuse benzodiazepine (BZD).To explore the rate of adu...

Surgical treatment of fibroids for subfertility.

Jan 30, 2020

Fibroids are the most common benign tumours of the female genital tract and are associated with numerous clinical problems including a possible negative impact on fertility. In women requesting preser...

Blue-blocking glasses as additive treatment for mania: Effects on actigraphy-derived sleep parameters.

Jan 24, 2020

Improvement of sleep is a central treatment goal for patients in a manic state. Blue-blocking (BB) glasses as adjunctive treatment hasten overall recovery from mania. This method is an evolvement from...

[Dynamic neuropathology of tauopathy].

Jan 24, 2020

Tauopathy is defined as abnormal accumulation of aberrantly phosphorylated microtubule-associated protein tau in the central nervous system, best demonstrated by immunocytochemistry using anti-tau ant...

Psychiatric-Based Pediatric ED Visits: Addressing Inadequate Evaluation & Treatment

Jan 24, 2020

Currently configured as urgent medical care facilities, emergency departments (EDs) typically lack the expertise required to appropriately assist psychiatric populations. It is estimated that greater ...

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