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Psychiatry General

Association of a Reproducible Epigenetic Risk Profile for Schizophrenia With Brain Methylation and Function.

Feb 13, 2020

Schizophrenia is a severe mental disorder in which epigenetic mechanisms may contribute to illness risk. Epigenetic profiles can be derived from blood cells, but to our knowledge, it is unknown whethe...

Why is Music Therapeutic for Neurological Disorders?

Feb 13, 2020

Music has cognitive, psychosocial, behavioral and motor benefits for people with neurological disorders such as dementia, stroke, Parkinson's disease and Autism Spectrum Disorder. Here we discuss seve...

Phosphates in medications: Impact on Dialysis Patients


Feb 13, 2020

Maintaining phosphorus balance in in-center hemodialysis (ICHD) patients is problematic despite recommended dietary restriction, dialysis, and phosphate binder use. Rarely is P content in prescribed m...

Neuroendocrine Effects of Naltrexone Versus Nalmefene

Feb 13, 2020

Naltrexone and nalmefene are approved for the treatment of alcohol use disorders, in different countries. Naltrexone is also approved for the treatment for opioid use disorders, most recently in a dep...

Estimating the impact of wide scale uptake of screening and medications for opioid use disorder in US prisons and jails.

Feb 13, 2020

Medications for opioid use disorder (OUD) are the most effective treatment for OUD, but uptake of these life-saving medications has been extremely limited in US prisons and jail settings, and limited ...

Trajectories of Retention in Opioid Agonist Therapy

Feb 13, 2020

Long-term engagement in opioid agonist therapy (OAT) has been consistently associated with reduced risk for morbidity and mortality in people with opioid use disorder (OUD). However, the dynamic natur...

Psychosocial Factors Associated with Sleep Quality and Duration Among Older Adults with Chronic Pain.

Feb 13, 2020

Sleep complaints are common among older adults with chronic pain. Because of the risk of significant side effects, sleep medications are not recommended as first-line treatments. Little is known about...

Sedentary Behavior, Activity Linked to Depression at Age 18

Feb 13, 2020

THURSDAY, Feb. 13, 2020 (HealthDay News) -- Sedentary behavior throughout adolescence is associated with the risk for depressive symptoms at age 18 years, according to a study published online Feb. 11...

Heroin Use Almost Doubled from 2002-2018

Feb 12, 2020

WEDNESDAY, Feb. 12, 2020 (HealthDay News) -- The prevalence of heroin use, heroin use disorder, and heroin injection increased from 2002 to 2018, according to a research letter published in the Feb. 1...

Brain MRIs ID Racial Differences in Pain Response

Feb 11, 2020

TUESDAY, Feb. 11, 2020 (HealthDay News) -- Racial differences in pain may be rooted in life experience, rather than intrinsic biology, according to a study published online Feb. 3 in Nature Human Beha...

Insomnia, sleepiness, anxiety and depression among different types of gamers in African countries.

Feb 10, 2020

Gaming has increasingly become a part of life in Africa. Currently, no data on gaming disorders or their association with mental disorders exist for African countries. This study for the first time in...

Association between upper extremity dysfunction and sleep disturbance in an elderly general population.

Feb 10, 2020

Several upper extremity disorders are associated with sleep disturbance in patient populations. This study evaluated the relation between self-assessment of upper extremity function and sleep disturba...

Impact of skeletal muscle mass on postoperative delirium in patients undergoing free flap repair after oral cancer resection.

Feb 10, 2020

Postoperative delirium (POD) is a major risk factor for an extended hospital stay and higher costs, and is associated with increased mortality. The incidence of POD is high in free flap procedures, an...

Update on the pharmacologic management of narcolepsy: mechanisms of action and clinical implications.

Feb 10, 2020

Narcolepsy is a chronic, debilitating neurological disorder of sleep-wake state instability. This instability underlies all narcolepsy symptoms, including excessive daytime sleepiness (EDS), symptoms ...

Quality of life and its relation with nutritional status in patients with incurable cancer in palliative care.

Feb 10, 2020

Nutritional impairment is common in cancer patients and adversely affects quality of life (QoL). The aim of this study was to investigate the association between nutritional status and QoL in incurabl...

Fluctuating asymmetry in patients with schizophrenia is related to hallucinations and thought disorganisation.

Feb 10, 2020

Fluctuating asymmetry represents the degree to which the right and left side of the body are asymmetrical, and is a sign of developmental instability. Higher levels of fluctuating asymmetry have been ...

Interaction between TNF-α and oxidative stress status in first-episode drug-naïve schizophrenia.

Feb 10, 2020

There has been evidence that the disturbances of TNF-α and the oxidative stress (OxS) status are involved in the mechanism of schizophrenia. However, the results of their levels in schizophrenia are ...

Altered serum microRNA expression profile in subjects with heroin and methamphetamine use disorder.

Feb 10, 2020

Drug abuse is one of the most severe global social and public health problems, especially in China. However, objective blood biomarkers that are easy to detect are still in great need. This study was ...

Effects of Transcutaneous Electrical Nerve Stimulation on Pain, Pulmonary Function, and Respiratory Muscle Strength After Posterolateral Thoracotomy: A Randomized Controlled Trial.

Feb 10, 2020

To evaluate the effects of transcutaneous electrical nerve stimulation (TENS) compared to placebo TENS and a control group on pain, pulmonary function, respiratory muscle strength, and analgesic medic...

Negative and disorganized symptoms mediate the relationship between verbal learning and global functioning in adolescents with early-onset psychosis.

Feb 10, 2020

Neurocognitive deficits are associated with impaired global functioning and psychotic symptoms. However, whether symptoms can mediate the relationship between neurocognition and global functioning in ...

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