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Psychiatry General

Effects of CST3 Gene G73A Polymorphism on Cystatin C in a Prospective Multiethnic Cohort Study.

Feb 13, 2020

G73A polymorphism in the CST3 gene of cystatin C has been associated with Alzheimer's disease, age-related macular degeneration, and cardiovascular disease. However, studies investigating the influenc...

Novel tau filament fold in corticobasal degeneration.

Feb 13, 2020

Corticobasal degeneration (CBD) is a neurodegenerative tauopathy that is characterised by motor and cognitive disturbances. A higher frequency of the H1 haplotype of MAPT, the tau gene, is present in ...

Validity and characteristics of patient-evaluated adherence to medication via smartphones in patients with bipolar disorder: exploratory reanalyses on pooled data from the MONARCA I and II trials.

Feb 13, 2020

Non-adherence to medication is associated with increased risk of relapse in patients with bipolar disorder (BD).To (1) validate patient-evaluated adherence to medication measured via smartphones again...

Complex Combination Pharmacotherapy for Bipolar Disorder: Knowing When Less Is More or More Is Better.

Feb 13, 2020

Combination pharmacotherapy for bipolar disorder is commonplace and often reflects the severity and complexity of the illness and the comorbid conditions frequently associated with it. Across treatmen...

Opposing Changes in the Functional Architecture of Large-Scale Networks in Bipolar Mania and Depression.

Feb 13, 2020

Manic and depressive phases of bipolar disorder (BD) show opposite symptoms in psychomotor, thought, and affective dimensions. Neuronally, these may depend on distinct patterns of alterations in the f...

The Mental Health Crisis Among Teens

Feb 13, 2020

The first signs of a problem started to emerge around 2014: More young people said they felt overwhelmed and depressed in national surveys. College counseling centers reported sharp increases in the n...

Case report: manic episode with psychotic symptoms induced by hyponatremia.

Feb 13, 2020

In the literature, several cases of an association between hyponatremia and psychotic symptoms have been reported. We present the case of a young Caucasian male presenting with rapid, incoherent spee...

LSD Overdoses: Three Case Reports.

Feb 13, 2020

In academic settings around the world, there is a resurgence of interest in using psychedelic substances for the treatment of addictions, posttraumatic stress disorder, depression, anxiety, and other ...

Comparison of Rhinoplasty Patients Informed With Standard Verbal Information in Preoperative Period and Rhinoplasty Patients Informed and Treated With Visual Information Through Catalog in Terms of the Development of Agitation, Edema and Ecchymose in the Postoperative Period.

Feb 13, 2020

In this study, we aimed to compare the effects of standard verbal information in the preoperative period and the information by visual expression and physical applications in the development of agitat...

Identification of TNFA influencing MDD risk and clinical features in Han Chinese.

Feb 13, 2020

Our recent genetic-neuroimaging study observed that the rs1799724 polymorphism within the TNFA gene encoding TNF-α selectively affects the anatomy of visual cortex in patients with MDD. In this study...

Kellner's Symptom Questionnaire, a Highly Sensitive Patient-Reported Outcome Measure: Systematic Review of Clinimetric Properties.

Feb 13, 2020

Patient-reported outcomes (PROs) are of increasing importance in clinical medicine. However, their evaluation by classic psychometric methods carries considerable limitations. The clinimetric approach...

Prospective 3-arm study on pain and epithelial healing after corneal crosslinking.

Feb 13, 2020

To investigate the effect of 3 regimes on pain and wound healing after corneal crosslinking (CXL).Tertiary academic referral center, Utrecht, the Netherlands.Prospective cohort study.Consecutive progr...

Specific cognitive correlates of the quality of life of extremely preterm school-aged children without major neurodevelopmental disability.

Feb 13, 2020

We examined how specific cognitive behavioral impairments impacted quality of life (QoL) within a large multicenter cohort of 7-10 year olds surviving extremely preterm (EPT) without major neurodevelo...

Indole Tryptophan Metabolism and Cytokine S100B in Children with Attention-Deficit/Hyperactivity Disorder: Daily Fluctuations, Responses to Methylphenidate, and Interrelationship with Depressive Symptomatology.

Feb 13, 2020

Indole tryptophan metabolites (ITMs), mainly produced at the gastrointestinal level, participate in bidirectional gut-brain communication and have been implicated in neuropsychiatric pathologies, inc...

First report of Davaneidae and Strongylida parasitizing Ramphocelus carbo (Aves: Passeriformes: Thraupidae) in the southwest of the Brazilian Amazon region.

Feb 13, 2020

In Brazil, species of the genus Ramphocelus with the presence of various endoparasites have already been reported. Coccidia have been the parasites most frequently found. All species of this genus hav...

The Prevalence and Incidence of Attention-deficit/Hyperactivity Disorder in the Veterans Health Administration From 2009 to 2016.

Feb 13, 2020

The prevalence and incidence of attention-deficit/hyperactivity disorder (ADHD) have increased substantially among children and adolescents over the past decade; however, little is known regarding tre...

Single Molecule Dye Organics with Multi-electrons Redox as Cathode Material for Li Battery.

Feb 13, 2020

Dissolution loss is the biggest issue for the organic electrode material, and nowadays the most popular strategy is to synthesize polymer or add much conductive carbon. In this paper, the issue is wel...

Design and Characterization of an Icosahedral Protein Cage Formed by a Double-Fusion Protein Containing Three Distinct Symmetry Elements.

Feb 13, 2020

Exploiting simple types of symmetry common to many natural protein oligomers as a starting point, several recent studies have succeeded in engineering complex self-assembling protein architectures rem...

Drug prescription patterns and factors associated with polypharmacy in >1 million older adults in Tokyo.

Feb 13, 2020

To determine the patterns of concomitant drug use for chronic diseases and examine the risk factors of polypharmacy in older outpatients.Data were extracted from an anonymized health insurance claims ...

Parkinson's disease, aging and adult neurogenesis: Wnt/β-catenin signalling as the key to unlock the mystery of endogenous brain repair.

Feb 13, 2020

A common hallmark of age-dependent neurodegenerative diseases is an impairment of adult neurogenesis. Wingless-type mouse mammary tumor virus integration site (Wnt)/β-catenin (WβC) signalling is a v...

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