Advertisement

Psychiatry General

TRPV1 activation alleviates cognitive and synaptic plasticity impairments through inhibiting AMPAR endocytosis in APP23/PS45 mouse model of Alzheimer's disease.

Feb 17, 2020

Alzheimer's disease (AD) is one of the most common causes of neurodegenerative diseases in the elderly. The accumulation of amyloid-β (Aβ) peptides is one of the pathological hallmarks of AD and lea...

Antidepressant Target Dose Optimization and Control of Severe Asthma Exacerbations in Uninsured and Underinsured Patients with Anxiety and/or Depression.

Feb 17, 2020

Generalized anxiety disorder (GAD) and major depressive disorder (MDD) are prevalent in patients with asthma. These disorders may increase asthma severity and decrease asthma control. No studies have ...

The impact of an enhanced recovery after minimally invasive surgery program on opioid use in gynecologic oncology patients undergoing hysterectomy.

Feb 17, 2020

To evaluate the effects of an enhanced recovery after minimally invasive surgery (MIS-ERAS) protocol on opioid requirements and post-operative pain in patients undergoing minimally invasive hysterecto...

Modeling Combination HCV Treatment and Prevention Strategies in a Network of People Who Inject Drugs in the USA.

Feb 17, 2020

HCV treatment as prevention (TasP) strategies can contribute to HCV micro-elimination, yet complimentary interventions like opioid agonist therapies (OAT) and syringe services programs (SSP) may impro...

Safety aspects of opioid-naïve patients with high-grade glioma treated with D,L-Methadone: an observational case series.

Feb 17, 2020

It was suggested that D, L-Methadone might improve the clinical course of glioma patients. Owing to massive press coverage, patients demand the prescription of D, L-Methadone, but regarding its adjunc...

A randomised, double-blind, crossover, dose ranging study to determine the optimal dose of oral opioid to treat breakthrough pain for patients with advanced cancer already established on regular opioids.

Feb 17, 2020

Pain in people with advanced cancer is prevalent. When a stable dose of opioids is established, people still experience episodic breakthrough pain for which dosing of an immediate release opioid is us...

Associations between Neighborhood-Level Factors and Opioid-Related Mortality: A Multilevel Analysis using Death Certificate Data.

Feb 17, 2020

To identify associations between opioid-related mortality and neighborhood-level risk factors.Cross-sectional study.Massachusetts, USA.Using 2011-2014 Massachusetts death certificate data, we identifi...

Molecular heterogeneity in breast carcinoma cells with increased invasive capacities.

Feb 17, 2020

Background Metastatic progression of breast cancer is still a challenge in clinical oncology. Therefore, an elucidation how carcinoma cells belonging to different breast cancer subtypes realize their ...

U.S. Life Expectancy to Reach 85 by 2060

Feb 14, 2020

FRIDAY, Feb. 14, 2020 (HealthDay News) -- Nearly a quarter of all U.S. residents will be older than 65 by 2060, and life expectancy will reach an all-time high of 85 by that year, according to the U.S...

Sleep time and sleep-related symptoms across two generations - results of the community-based RHINE and RHINESSA studies.

Feb 13, 2020

To analyze the association between sleep-related symptoms and sleep length in parents and their children in relation to other risk factors in both generations.The participants were parents (n = 5,85...

Adolescent Sjogren's syndrome presenting as psychosis: a case series.

Feb 13, 2020

Neurological involvement has been reported in up to 80% of adults with Primary Sjogren's syndrome (pSS) with psychiatric abnormalities including anxiety, depression, and cognitive dysfunction being co...

Resting-state brain network topological properties and the correlation with neuropsychological assessment in adolescent narcolepsy.

Feb 13, 2020

To evaluate functional connectivity and topological properties of brain networks, and to investigate the association between brain topological properties and neuropsychiatric behaviors in adolescent n...

Hypnotic prescription by GPs is associated with their personal drug consumption but not by their insomnia status.

Feb 13, 2020

French general practitioners (GPs) are known to widely prescribe medications to treat insomnia despite their negative effects. GPs' easy access to self-medication may affect their mental representatio...

An Investigation of Psychosis Subgroups With Prognostic Validation and Exploration of Genetic Underpinnings: The PsyCourse Study.

Feb 13, 2020

Identifying psychosis subgroups could improve clinical and research precision. Research has focused on symptom subgroups, but there is a need to consider a broader clinical spectrum, disentangle illne...

Psychotic Experiences Are Associated With Paternal Age But Not With Delayed Fatherhood in a Large, Multinational, Community Sample.

Feb 13, 2020

Advanced paternal age has been consistently associated with an increased risk of schizophrenia. It is less known if such an association also exists with subclinical/attenuated forms of psychosis. Addi...

Birth weight, family history of diabetes and diabetes onset in schizophrenia.

Feb 13, 2020

The prevalence of diabetes in schizophrenia is twice that in the general population, but there are few reliable predictors of which individuals will develop glucose dysregulation.To test if abnormal b...

Anomalies in language as a biomarker for schizophrenia.

Feb 13, 2020

After more than a century of neuroscience research, reproducible, clinically relevant biomarkers for schizophrenia have not yet been established. This article reviews current advances in evaluating th...

Impact of Cooling on Lowering the Pain Threshold in Patients Undergoing Sclerotherapy.

Feb 13, 2020

Liquid sclerotherapy is the treatment of choice for telangiectasias. However, pain caused by the procedure is a barrier to treatment adherence by patients.To evaluate the use of skin cooling for the m...

A novel tool showing that perceptions of adverse social relationships in childhood were linked with mental health problems and suicidal experiences: Validation of the English version of the History of Social Punishment (HoSP) scale.

Feb 13, 2020

There is robust evidence for relationships between adverse events experienced in childhood and mental health problems experienced as an adult. However, the measurement of perceptions of different type...

Analyzing the co-localization of substantia nigra hyper-echogenicities and iron accumulation in Parkinson's disease: A multi-modal atlas study with transcranial ultrasound and MRI.

Feb 13, 2020

Transcranial B-mode sonography (TCS) can detect hyperechogenic speckles in the area of the substantia nigra (SN) in Parkinson's disease (PD). These speckles correlate with iron accumulation in the SN ...

SUBSPECIALTIES

Advertisement