Mar 05, 2020

Patterns of opioid overprescribing following arthroplasty likely developed given that poor pain control can diminish patient satisfaction, delay disposition, and lead to complications. Recently, inter...

Mar 04, 2020

WEDNESDAY, March 4, 2020 (HealthDay News) -- Electrical shock devices (ESDs) used to reduce aggression and self-harm in patients with autism and other developmental disabilities will be banned, the U....

Mar 04, 2020

WEDNESDAY, March 4, 2020 (HealthDay News) -- From 2007 to 2018, there were substantial increases in list and net prices of branded drugs in the United States, according to a study published in the Mar...

Mar 02, 2020

Advances in neuroimaging open up the possibility for new powerful tools to be developed that potentially can be applied to clinical populations to improve the diagnosis of neurological disorders, incl...

Mar 02, 2020

Early-stage romantic involvement may resemble hypomania in its manifestation on behavioral, physiological, and psychological levels. Previous research suggests that self-reported sleep duration may di...

Mar 02, 2020

The study objectives were to examined accidental risks associated with insomnia or hypnotic medications, and how these risk factors interact with sex and age.A population-based sample of 3413 adults (...

Mar 02, 2020

Insomnia commonly co-occurs with chronic migraines (CM). Non-pharmacological treatments for insomnia in CM patients remain understudied. This is a proof-of-concept study, which aims to evaluate the fe...

Mar 02, 2020

Digital cognitive behavioural therapy (dCBT) is an effective treatment for chronic insomnia and also improves well-being and quality of life (QoL). We assessed whether these benefits are sustained and...

Mar 02, 2020

Ambient air pollution affects neurological function, but its association with schizophrenia risk is unclear. We investigated exposure to nitrogen oxides (NO) as a whole and nitrogen dioxide (NO) speci...

Mar 02, 2020

Olanzapine has been used for the treatment of schizophrenia and other mental disorders. However, it is associated with serious weight gain and other metabolic side-effects. The antagonistic affinity o...

Mar 02, 2020

Auditory hallucinations (AH) are one of the core symptoms of schizophrenia (SZ) and constitute a significant source of suffering and disability. One third of SZ patients experience pharmacology-resist...

Mar 02, 2020

Comorbidity between Substance use disorders (SUD) and psychotic disorders is common but the temporal relation of the first episodes of SUD and psychosis and how it affects the disorders has not been e...

Mar 02, 2020

Sorption onto clays (montmorillonite and kaolinite), oxidation and sorption by manganese oxides (synthesized MnO and natural MnO), and coupled sorption-oxidation experiments were conducted for the rem...

Mar 02, 2020

The Hypothalamus-Pituitary-Gonadal (HPG)-axis, and testosterone in particular, play an important role in social motivational behavior. Socially avoidant behavior, characteristic of social anxiety diso...

Mar 02, 2020

Throughout the world, ethanol is both an important commercial commodity and a source of major medical and social problems. Ethanol readily passes through biological membranes and distributes throughou...

Mar 02, 2020

This study aimed to compare the EuroQol 5-dimension 5-level questionnaire (EQ-5D-5L), the visual analogue scale (VAS), and the Kidney Disease Quality of Life 36-Item Short-Form Survey (KDQOL-36) score...

Mar 02, 2020

The safety and efficacy of opioids are compromised as analgesic tolerance develops. Opioids are also ineffective against neuropathic pain. Recent reports have suggested that inhibitors of the epiderma...

Mar 02, 2020

Opioid agonist activation at the mu opioid receptor (MOR) can lead to a wide variety of physiological responses. Many opioid agonists share the ability to selectively and preferentially activate speci...

Mar 02, 2020

Morphine-3-glucuronide (M3G), the main metabolite of morphine, has been implicated in the development of tolerance and of opioid-induced hyperalgesia, both limiting the analgesic use of morphine. We e...

Mar 02, 2020

In the past decade, there has been a rising trend in the emergency department (ED) visits in the US and these visits carry a significant burden of prescription opioids. This study utilized the latest ...