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Psychiatry General

Measuring Opioid Withdrawal in a Phase 3 Study of a New Analgesic, NKTR-181 (Oxycodegol), in Patients with Moderate to Severe Chronic Low Back Pain.

Mar 10, 2020

To evaluate the SUMMIT-07 trial opioid withdrawal results of NKTR-181 (oxycodegol), a new molecular entity mu-opioid receptor agonist.Phase 3, enriched-enrollment, double-blind, randomized-withdrawal ...

Risk of New Fractures in Vertebroplasty for Multiple Myeloma. A Retrospective Study.

Mar 10, 2020

Vertebroplasty is a percutaneous minimally invasive procedure indicated for vertebral collapse pain treatment. Among the known complications of the procedure is the augmented risk of new vertebral fra...

Full agonist opioid prescribing by primary care clinicians after buprenorphine training.

Mar 10, 2020

While primary care clinicians are being trained to use buprenorphine for the treatment of Opioid Use Disorder (OUD) in order to increase access to addiction treatment, it is not known what impact suc...

A Phylogenetic Analysis of HCV Transmission, Relapse, and Reinfection Among People Who Inject Drugs Receiving Opioid Agonist Therapy.

Mar 10, 2020

Understanding hepatitis C virus (HCV) transmission among people who inject drugs (PWID) is essential for HCV elimination. We aimed to differentiate reinfections from treatment failures and to identify...

Prenatal exposure to methadone or buprenorphine and long-term outcomes: A meta-analysis.

Mar 09, 2020

To combine meta-analyses of multiple long-term outcomes in children prenatally exposed to methadone or buprenorphine through their mothers' Opioid maintenance therapy (OMT) with a systematic review of...

Gabapentin Seems Efficacious for Alcohol Use Disorder

Mar 09, 2020

MONDAY, March 9, 2020 (HealthDay News) -- Gabapentin appears to be efficacious for the treatment of alcohol use disorder (AUD), especially among those with high alcohol withdrawal, according to a stud...

New Tool Measures Quality of Life With Autism Across Life Span

Mar 06, 2020

FRIDAY, March 27, 2020 (HealthDay News) -- A new online survey appears to be a feasible and acceptable method for assessing patient- and parent-reported outcomes and quality of life for people with au...

Heartfulness meditation improves sleep in chronic insomnia.

Mar 05, 2020

: Chronic insomnia is characterized by disturbed sleep that occurs despite adequate opportunity and circumstances to sleep. Many patients with chronic insomnia have comorbid mental illnesses or medica...

The effects of digital cognitive behavioural therapy for insomnia on cognitive function: A randomised, controlled trial.

Mar 05, 2020

We sought to examine the impact of digital cognitive behavioural therapy (dCBT) for insomnia on both self-reported cognitive impairment and objective cognitive performance.The DISCO trial was an onlin...

96-week results of a dual therapy with darunavir/ritonavir plus rilpivirine once a day triple therapy in patients with suppressed viraemia: virological success and non-HIV related morbidity evaluation.

Mar 05, 2020

Antiretroviral therapies have been tested with the goal of maintaining virological suppression with a particular attention in limiting drug-related toxicity. With this aim we designed the DUAL study: ...

The risk of mental disorders in patients with disorders/differences of sex differentiation/development (DSD) and Y chromosome.

Mar 05, 2020

Patients with disorders/differences of sex differentiation/development (DSD) are exposed to mental and physical suffering. The aim of the study was to assess the mental state and the risk of psycholog...

Digital Cognitive Behavioral Therapy for Insomnia for Adolescents With Mental Health Problems: Results From a Feasibility Open Trial.

Mar 05, 2020

Insomnia in adolescents is common, persistent, and associated with poor mental health including anxiety and depression. Insomnia in adolescents attending child mental health services is seldom directl...

Association analysis of potentially functional variants within 8p12 with schizophrenia in the Han Chinese population.

Mar 05, 2020

Chromosome 8p12 was first identified as a schizophrenia (SCZ) risk locus in Chinese populations and replicated in European populations. However, the underlying functional variants still need to be fu...

Catatonia in Anti-N-Methyl-D-Aspartate (NMDA) Receptor Encephalitis Misdiagnosed as Schizophrenia.

Mar 05, 2020

Anti-N-Mmethyl-D-aspartate receptor encephalitis is an autoimmune disease of the central nervous system with prominent neurologic and psychiatric features. Symptoms appear progressively and sometimes...

Quality of life and its social determinants for patients with schizophrenia and family caregivers in Cambodia.

Mar 05, 2020

Due to inadequate human and financial resource support, the development of mental health services in Cambodia has been undertaken by various non-governmental organizations (NGOs). Schizophrenia is the...

Trajectory and early predictors of apathy development in first-episode psychosis and healthy controls: a 10-year follow-up study.

Mar 05, 2020

Apathy is prevalent in first-episode psychosis (FEP) and associated with reduced global functioning. Investigations of the trajectory of apathy and its early predictors are needed to develop new treat...

Pain assessment and management in children in the postoperative period: A review of the most commonly used postoperative pain assessment tools, new diagnostic methods and the latest guidelines for postoperative pain therapy in children.

Mar 05, 2020

Pain is one of the most common complaints expressed by hospital patients and is the main reason they seek medical help. Pain is always subjective, so its severity should be assessed individually for e...

Workshop on the Development and Evaluation of Digital Therapeutics for Health Behavior Change: Science, Methods, and Projects.

Mar 05, 2020

The health care field has integrated advances into digital technology at an accelerating pace to improve health behavior, health care delivery, and cost-effectiveness of care. The realm of behavioral ...

Implementation Effectiveness of a Parent-Directed YouTube Video ("It Doesn't Have To Hurt") on Evidence-Based Strategies to Manage Needle Pain: Descriptive Survey Study.

Mar 05, 2020

Despite the availability of high-quality evidence and clinical practice guidelines for the effective management of pediatric pain, this evidence is rarely used in practice for managing children's pain...

Abstinence from Masturbation and Hypersexuality.

Mar 05, 2020

Despite the lack of evidence for negative health effects of masturbation, abstinence from masturbation is frequently recommended as a strategy to improve one's sexual self-regulation. We adopted a fra...

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