Apr 12, 2020

Mental disorders are typically defined as distinct diagnostic entities, but similar patterns of clinical and cognitive impairments are frequently found across diagnostic groups. We investigated whethe...

Apr 12, 2020

Development of a support system for families caring for people with schizophrenia in routine psychiatric care settings is an important issue worldwide. Regional mental health systems are inadequate fo...

Apr 12, 2020

Subjective recovery is a personally perceived recovery involving other factors beyond clinical recovery. This study aims at investigating the factors related to subjective recovery in patients with sc...

Apr 12, 2020

To metasynthesize the results of qualitative studies on the factors that affect parents' participation in pain management for their infants during procedures in the NICU.We conducted a literature sear...

Apr 12, 2020

There have been recent reports that reconsolidation-based interventions attenuate drug reward memories in rodents. The insular cortex (IC) is an essential part of neural circuits that underlie cue-dru...

Apr 12, 2020

To examine factors differentiating individuals whose first suicide attempt was during childhood (ages 5-12 yrs) from those who first attempted suicide during adolescence (13-19 yrs) and during adult...

Apr 12, 2020

Positron emission tomography (PET) has great benefits for developing therapeutics and quantifying pathological markers in neuropsychiatric disorders. This study aimed to firstly demonstrate the feasib...

Apr 12, 2020

Cistanche tubulosa is a precious traditional Chinese medicine that has been widely used in the treatment of osteoporosis and Alzheimer's disease. Echinacoside and acteoside are the main active constit...

Apr 12, 2020

Ferrous sulfate (FeSO)-directed dual-cross-linked hydrogels were designed for application in single-syringe injections. The use of FeSO, rather than other iron salts, can modulate the gelation time an...

Apr 12, 2020

Alzheimer's disease (AD) is the leading cause of dementia, accounting for 70% of cases worldwide. By 2050, dementia prevalence will have tripled, with most new cases occurring in low- and middle-incom...

Apr 12, 2020

In the context of the public health burden posed by increases in Alzheimer's Disease (AD) prevalence around the globe and the related research efforts to identify modifiable risk factors for the disea...

Apr 12, 2020

Bipolar disorder (BD) is a mental disorder characterized by mood fluctuations between an acute episodic state of either mania or depression and a clinically remitted state. Dysfunction of large-scale ...

Apr 12, 2020

Bipolar disorder (BD) is a chronic mental illness characterized by changes in mood that alternate between mania and hypomania or between depression and mixed states, often associated with functional i...

Apr 12, 2020

It remains unclear whether specific clinical factors contribute to heterogeneity in the timing of the onset of nonfatal suicidal behavior. This knowledge could have important implications for suicide ...

Apr 12, 2020

Lithium is the mainstay for the maintenance treatment of mood disorders (MD), but its efficacy needs to be weighed against its side effects profile. Here, we assessed retrospectively the clinical resp...

Apr 12, 2020

To reanalyze Aristotle's classic lecture, "On melancholy," with current clinical interpretations METHOD: The full lecture is described and interpreted in a new translation.Aristotle's lecture has been...

Apr 12, 2020

The ability of environmental pollutants to alter the epigenome with resultant development of behavioral alterations has received more attention in recent years. These alterations can be transmitted an...

Apr 12, 2020

Anxiety disorders are often preceded by interpersonal stress; however, most individuals who experience stress do not develop anxiety, making it difficult to predict who is most susceptible to stress. ...

Apr 12, 2020

Few studies have attempted to identify how distinct dimensions of maternal prenatal affective symptoms relate to offspring psychopathology. We defined latent dimensions of women's prenatal affective s...

Apr 12, 2020

Air pollution is associated with adverse impacts on the brain, including cognitive decline and increased incidence of dementia, depression and anxiety; however, underlying mechanisms remain unclear. W...