Apr 28, 2020

The aim of the present study was to investigate various aspects of tiagabine (TGB) effectiveness in Bulgarian patients with drug-resistant epilepsy. This open, prospective study recruited the patients...

Apr 28, 2020

Sleep is one of the most important body mechanisms responsible for the proper functioning of human body. Cyclic alternating patterns (CAP) play an indispensable role in the analysis of sleep quality a...

Apr 28, 2020

At the extreme spectrum of consciousness during sleep, some patients with rare hypersomnias reported experiencing a specific night 'blackout' when sleeping, i.e., an absence of experiences or recall o...

Apr 28, 2020

Impairments of social cognition are considered core features of schizophrenia and are established predictors of social functioning. However, affective aspects of social cognition including empathy hav...

Apr 28, 2020

Early life adversity in humans is linked to cognitive deficits and increased risk of mental illnesses, including depression, bipolar disorder, and schizophrenia, with evidence for different vulnerabil...

Apr 28, 2020

Normal brain-aging occurs at all structural levels. Excessive pathophysiological changes in the brain, beyond the normal one, are implicated in the etiology of brain disorders such as severe forms of ...

Apr 28, 2020

Schizophrenia (SZ) is found to be associated with dysconnectivity between the various regions of the brain. These aberrant connections in brain networks responsible for various mental processes in sch...

Apr 28, 2020

Some patients with schizophrenia have impaired hypothalamic-pituitary-adrenal axis function. However, there is a dearth of studies focusing on corticotropin-releasing hormone (CRH) levels in the brain...

Apr 28, 2020

Physiological regulation is so fundamental to survival that natural selection has greatly favored the evolution of robust regulatory systems that use both reactive and preemptive responses to mitigate...

Apr 28, 2020

Family caregivers encounter many challenges when managing pain for their loved ones. ​​There is a lack of clear recommendations on how to prepare caregivers in pain management.To evaluate existing...

Apr 28, 2020

NIMHANS ECHO (Extension for Community Healthcare Outcomes) model uses a video conferencing app to connect multiple community health care teams simultaneously with addiction treatment specialists and b...

Apr 28, 2020

Alzheimer's disease (AD) is a progressive brain disorder characterized by memory loss and the accumulation of two insoluble protein aggregates, tau neurofibrillary tangles and beta-amyloid plaques. Wi...

Apr 28, 2020

Defective proprioceptive integration may play a role in the pathophysiology of motor symptoms in Parkinson's disease (PD). Dysfunction related to proprioceptively-evoked postural reactions in PD patie...

Apr 28, 2020

Several lines of evidence from neuropathological studies, human genetics, in vitro aggregation studies and cellular and animal models support the hypothesis that aSyn plays a central role in the forma...

Apr 28, 2020

Stigma is a known correlate of well-being for many neurological conditions. Perceived control is also an important variable in models of adaptation to living with a health condition. The purpose of th...

Apr 28, 2020

Previous reports proposed prelemniscal radiations (Raprl) as a target to treat motor symptoms of Parkinson's disease, and this was found particularly effective to control rest and postural tremor. How...

Apr 28, 2020

According to Nemeth et al. (2011), pediatric mania is difficult to distinguish from childhood hyperactivity. Both share 3 common symptoms: distractibility, motoric hyperactivity, and talkativeness (Bi...

Apr 28, 2020

Patients with bipolar disorder experience a wide range of depressive and manic symptoms. Only 2 drugs are FDA-approved to treat episodes of both mania and depression in patients with bipolar disorder,...

Apr 28, 2020

Delirious mania is a life-threatening condition, presenting with symptoms of acute delirium and psychotic mania as a complication of medical or psychiatric condition. It is not recognized as a diagnos...

Apr 28, 2020

Long-term maintenance treatment is essential in management of bipolar I disorder (BP-I) to achieve mood stability, prevent recurrence of mood episodes and improve functioning. Aripiprazole once-monthl...