Jul 23, 2020

Bipolar disorder is one of the most common serious mental illnesses, affecting approximately 60 million people worldwide. Characterised by extreme alterations in mood, cognition, and behaviour, bipola...

Jul 23, 2020

Although chronic mania has been investigated, with several case reports and systematic retrospective cohort studies in the literature, it not a widely recognized entity. No specific definition for chr...

Jul 23, 2020

Although chronic mania has been investigated, with several case reports and systematic retrospective cohort studies in the literature, it not a widely recognized entity. No specific definition for chr...

Jul 23, 2020

Fragile X syndrome (FXS) is a genetic disorder caused by a trinucleotide (CGG) expansion mutation in the Fmr1 gene located on the X chromosome. It is characterized by hyperactivity, increased anxiety,...

Jul 23, 2020

The severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) pandemic has impacted all patient populations including pregnant mothers. There is an incomplete understanding of SARS-CoV-2 pathogenes...

Jul 23, 2020

Codeine and tramadol are commonly used analgesics in surgery. In 2013, the Food and Drug Administration (FDA) issued a contraindication to the use of codeine in tonsillectomy and adenoidectomy patient...

Jul 23, 2020

Postoperative pain management is challenging in low- and middle-income countries (LMICs). This study assesses the safety and efficacy of transversus abdominis plane (TAP) blocks as an adjunct for post...

Jul 23, 2020

Mitragynine is the most abundant psychoactive alkaloid derived from the leaves of (kratom), a tropical plant indigenous to regions of Southeast Asia. Mitragynine displays a moderate affinity to opioi...

Jul 23, 2020

Four xanthone derivatives were synthesized and evaluated as acetylcholinesterase inhibitors (AChEIs) with metal chelating ability and antioxidant ability against Alzheimer's disease (AD). Most of...

Jul 23, 2020

Dislocation after bipolar hip hemiarthroplasty is an uncommon complication. Although closed manoeuvre reduction under general anaesthesia is a common and effective method for dislocation of the hemiar...

Jul 23, 2020

Dementia is a risk factor for epilepsy. While seizures have a well-established association with Alzheimer's disease (AD), their association with dementia with Lewy bodies (DLB) is not established. We ...

Jul 23, 2020

Although previous studies have found that ADHD is characterized by a delay in cortical maturation, it is not clear whether this phenomenon was secondary to developmental trajectories in subcortical re...

Jul 23, 2020

Symptoms of attention-deficit hyperactivity disorder (ADHD) and conduct problems have been associated with heightened temporal discounting of reward value resulting in a preference for immediate over ...

Jul 23, 2020

Cognitive remediation is able to improve activation patterns in the frontal lobe but only few data on neuroconnectivity has been reported yet. Resting-state approach is a neuroimaging methodology with...

Jul 13, 2020

Many patients with depression do not respond sufficiently to antidepressant treatment, necessitating other treatment approaches. HMG-CoA reductase inhibitors (i.e. statins), which are frequently used ...

Jul 13, 2020

Women undergoing instrumental delivery are known to be at higher risk of urinary retention, which can lead to long term complications such as voiding dysfunction Nulliparous women undergo a pronounced...

Jul 13, 2020

Olive leaves are well known for their high polyphenol content and beneficial effects to human health. The two main phenolic compounds of olive leaves are oleuropein and 3-hydroxytyrosol. Use of olive ...

Jul 13, 2020

Characterize the state of the science in opioid policy research based on a literature review of opioid policy studies.We conducted a scoping review of studies evaluating the impact of U.S. state-level...

Jul 13, 2020

Methamphetamine use, with and without opioids, has increased substantially, but little is known about the sociodemographic characteristics, substance use patterns, or health profiles of individuals wh...

Jul 13, 2020

Delayed anesthesia recovery following endoscopic sinus surgery (ESS) can be an indicator of immediate complications and negatively impact healthcare efficiency. This study aims to examine clinical fac...