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Psychiatry General

Frailty Linked to Suicide Attempt Risk in Elderly US Veterans

May 10, 2023

The following is a summary of "Association of Frailty With Risk of Suicide Attempt in a National Cohort of US Veterans Aged 65 Years or Older," published in the February 2023 issue of Psychiatry by Ku...

Office-based Buprenorphine Treatment for Opioid Use Disorder: Cost-effectiveness

May 09, 2023

The following is a summary of "Cost-effectiveness of office-based buprenorphine treatment for opioid use disorder," published in the February 2023 issue of Drug and Alcohol Dependence by Qian et al. ...

Exploring the Cannabis Use & Sleep Quality: An Electronic Daily Diary Study of Adults

May 08, 2023

The following is a summary of "Cannabis use and sleep quality in daily life: An electronic daily diary study of adults starting cannabis for health concerns," published in the February 2023 issue of D...

Preoperative mechanical bowel preparation for gynecologic surgeries: a systematic review with meta-analysis.

May 08, 2023

To assess the efficacy and safety of mechanical bowel preparation before benign laparoscopic or vaginal gynecologic surgeries.Database searches of MEDLINE (PubMed), EMBASE (OVID), Cochrane Central Reg...

Unrevealing the shared genetic mechanisms underlying C-reactive protein and schizophrenia.

May 08, 2023

Longitudinal observational studies and Mendelian randomization research have obtained contradictory conclusions regarding the association between C-reactive protein (CRP) level and schizophrenia risk....

Gestational Exposure to Haloperidol Changes Cdkn1a and Apaf1 mRNA Expressions in Mouse Hippocampus.

May 08, 2023

The onset of schizophrenia is associated with both genetic and environmental risks during brain development. Environmental factors during pregnancy can represent risk factors for schizophrenia, and we...

Differences in the gut microbiome across typical ageing and in Parkinson's disease.

May 08, 2023

The microbiota-gut-brain axis' role in Parkinson's disease (PD) pathophysiology, and how this differs from typical ageing, is poorly understood. Presently, gut-bacterial diversity, taxonomic abundance...

Effects of Danggui-Shaoyao-San on central neuroendocrine and pharmacokinetics in female ovariectomized rats.

May 08, 2023

The traditional Chinese medicine formula Danggui-Shaoyao-San (DSS) has been reported to have estrogen-like effects and therapeutic effects on the symptoms of Alzheimer's disease (AD).To explore whethe...

Psychotic-like experiences in general population: Psychiatric comorbidity and impact on quality of life across lifespan.

May 08, 2023

In this study, we aimed to determine the prevalence of Psychotics-Like Experiences according to age group and their association with psychiatric disorders through these different age-group, as well as...

Unlocking the potential of snake venom-based molecules against the malaria, Chagas disease, and leishmaniasis triad.

May 08, 2023

Malaria, leishmaniasis and Chagas disease are vector-borne protozoal infections with a disproportionately high impact on the most fragile societies in the world, and despite malaria-focused research g...

Reduced Functional Connectivity of the Brain During Working Memory in Methamphetamine Use Disorder

May 04, 2023

The following is a summary of “Reduced neural functional connectivity during working memory performance in methamphetamine use disorder,” published in the February 2023 issue of Drug and Alcohol D...

Tracking the Trail of Opioids and Benzodiazepines: Kentucky's Prescription Monitoring Program

May 03, 2023

The following is a summary of “Mandatory prescription drug monitoring programs and overlapping prescriptions of opioids and benzodiazepines: Evidence from Kentucky," published in the February  2023...

Exploring the Therapeutic Effects of Smoked Cannabis on Polysubstance Use

May 02, 2023

The following is a summary of “Smoked cannabis reduces peak cocaine plasma levels and subjective effects in a controlled drug administration study of polysubstance use in men,” published in the Fe...

The Modulation of Fentanyl-depressed Respiration by Amphetamines in a Bidirectional Manner

May 01, 2023

The following is a summary of "Amphetamines modulate fentanyl-depressed respiration in a bidirectional manner," published in the February 2023 issue of Drug and Alcohol Dependence by Elder et al. ...

Frequency of antidepressant use and clinical characteristics of children and adolescents undergoing polysomnography: an observational study.

May 01, 2023

Antidepressants are increasingly used in children for various psychiatric disorders but also for sleep disorders such as insomnia; however, it is currently unknown how many children undergoing polysom...

Smoking status ameliorates cholinergic impairments in cortical inhibition in patients with schizophrenia.

May 01, 2023

Rationale Modulation of cortical excitability, in particular inhibition, is impaired in patients with schizophrenia. Chronic nicotine consumption, which is prevalent in this group, has been shown to a...

Analysis of Appendicitis Cases in the Japanese Adverse Drug Event Report (JADER) Database.

May 01, 2023

Appendicitis is one of the most common abdominal surgical emergencies worldwide; however, its causes remain poorly understood. The Japanese Adverse Drug Event Report (JADER) database is a spontaneous ...

Physicochemical Properties of Branded and Generic Infusion Fluid Preparations: Results of a Comparative Experimental Study on Type 2 Hypotonic Infusion Fluid.

May 01, 2023

In Japan, four different types of hypotonic infusion fluids, namely, types 1-4, are available and used depending on the patient's condition. Although branded and generic products for each type of hypo...

Effects of medial prefrontal transcranial alternating current stimulation on neural activity and connectivity in people with Huntington's disease and neurotypical controls.

May 01, 2023

We investigated the effects of transcranial alternating current stimulation (tACS) targeted to the medial prefrontal cortex (mPFC) on resting electroencephalographic (EEG) indices of oscillatory power...

Sublingual Dexmedetomidine for the Treatment of Agitation in Patients with Schizophrenia and Bipolar Disorder.

May 01, 2023

Acute agitation is common amongst individuals with bipolar disorder and schizophrenia and represents a medical emergency. Commonly used medications for agitation, such as benzodiazepines and antipsych...

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