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Psychiatry General

Restless legs syndrome in children and adolescents with attention-deficit/hyperactivity disorder: prevalence, mimic conditions, risk factors, and association with functional impairment.

Aug 24, 2020

To determine the prevalence of restless legs syndrome (RLS) and RLS-mimic conditions, the risk factors for RLS, and whether RLS contributes to functional impairment in children and adolescents with at...

Heme attenuates beta-endorphin levels in leukocytes of HIV positive individuals with chronic widespread pain.

Aug 24, 2020

The prevalence of chronic widespread pain (CWP) in people with HIV is high, yet the underlying mechanisms are elusive. Leukocytes synthesize the endogenous opioid, β-endorphin, within their endoplasm...

Effect of Maternal Eating Disorders on Pregnancy and Neonatal Outcomes

Aug 20, 2020

Eating disorders are prevalent among women of reproductive age, but the effects of bad eating habits on pregnancy and neonatal outcomes have not been well studied. The objective of this study is to as...

Lumateperone for the Treatment of Schizophrenia

Aug 20, 2020

There is currently no cure for schizophrenia, but the condition can be treated and managed. Lumateperone is an antipsychotic medication considered to be a potential treatment for schizophrenia. This s...

Psychiatric Disorders and the Risk of Subjection and Perpetration of Violence

Aug 20, 2020

Subjection to violence and perpetration of violence are the key outcomes in persons with psychiatric disorders. However, the occurrence and prevalence of these outcomes are yet to be clarified. This s...

Aripiprazole and the Risk of Adverse Psychiatric Events

Aug 20, 2020

Aripiprazole is an antipsychotic medication used to treat psychotic conditions like bipolar disorder and schizophrenia. Common side effects of aripiprazole include dizziness and drowsiness, but in som...

High-Potency Cannabis Use and Mental Health Outcomes

Aug 20, 2020

The consumption of cannabis is on the rise, so much so, that several countries across the globe have legalized its sale for personal and medical use. However, the use of high-potency cannabis is conti...

Anticholinergic Drugs and Risk of Dementia

Aug 20, 2020

Anticholinergic drugs block the action of acetylcholine and can treat several conditions like overactive bladder, COPD, and urinary incontinence. The use of anticholinergic drugs is linked with the in...

Paternal Use of Antidepressants and Offspring Outcomes

Aug 20, 2020

The use of antidepressants can cause severe side effects in the patients. However, little is known about the intake of antidepressants by parents and the outcomes in offsprings. The objective of this ...

Development of a Conceptual Model of Chronic Lymphocytic Leukemia to Better Understand the Patient Experience.

Aug 20, 2020

Understanding the patient experience is important for identifying the unmet need in chronic lymphocytic leukemia. The current study aimed to develop a comprehensive chronic lymphocytic leukemia concep...

The effects of bi-anodal tDCS over the prefrontal cortex regions with extracephalic references placement on insight levels, cardio-respiratory and autonomic functions in schizophrenia patients and exploratory biomarker analyses for treatment response.

Aug 20, 2020

We have previously shown the efficacy of bi-anodal transcranial direct current stimulation (tDCS) over the prefrontal cortex (PFC) regions with extracephalic references placement in improving negative...

Characteristics of white matter structural networks in chronic schizophrenia treated with clozapine or risperidone and those never-treated.

Aug 20, 2020

Despite its benefits, a major concern regarding antipsychotic treatment is its possible impact on the brain's structure and function. This study sought to explore the characteristics of white matter s...

Effects of haloperidol inhalation on MK-801- and memantine-induced locomotion in mice.

Aug 20, 2020

The administration of therapeutic agents is difficult in many patients, such as patients with post-operative delirium or dementia or patients with schizophrenia, who are upset in an emergency room. Th...

Differential Expression of Multiple Disease-Related Protein Groups Induced by Valproic Acid in Human SH-SY5Y Neuroblastoma Cells.

Aug 20, 2020

Valproic acid (VPA) is a multifunctional medication used for the treatment of epilepsy, mania associated with bipolar disorder, and migraine. The pharmacological effects of VPA involve a variety of ne...

Caring for the caregiver during COVID-19 outbreak: Does inclusive leadership improve psychological safety and curb psychological distress? A cross-sectional study.

Aug 20, 2020

Public health emergencies and epidemics shatter the assumptions of the world as a safe place. Healthcare workers are at the forefront of such pressures resulting from a persistent threat to their safe...

Prevalence and Correlates of Mental Health Problems in Norwegian Peacekeepers 18-38 Years Postdeployment.

Aug 20, 2020

Peacekeeping missions involve experiences that may impact the mental health of participating soldiers. However, research on the long-term mental health consequences of peacekeeping is sparse. The pres...

Insomnia as a mediating therapeutic target for depressive symptoms: A sub-analysis of participant data from two large randomized controlled trials of a digital sleep intervention.

Aug 20, 2020

Insomnia predicts the onset of depression, commonly co-presents with depression and often persists following depression remission. However, these conditions can be challenging to treat concurrently us...

Joint effect of diabetes and opiate use on all-cause and cause-specific mortality: the Golestan cohort study.

Aug 20, 2020

Many diabetic individuals use prescription and non-prescription opioids and opiates. We aimed to investigate the joint effect of diabetes and opiate use on all-cause and cause-specific mortality.Goles...

State of the art treatment options for Pakistan's opioid, alcohol and methamphetamine crisis.

Aug 20, 2020

The literature review was planned to discuss the extent of opioid, alcohol and methamphetamine use disorder in Pakistan, the neurobiology of opioids, alcohol and methamphetamine, the importance of med...

Comparing perspectives on medication treatment for opioid use disorder between national samples of primary care trainee physicians and attending physicians.

Aug 20, 2020

Most people with opioid use disorder (OUD) are not treated with FDA-approved medications methadone, buprenorphine, or naltrexone. Expanding capacity for evidence-based OUD medication in primary care i...

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