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Psychiatry General

Effect of adjunctive pimavanserin on suicidal ideation in patients with major depression: Analysis of the CLARITY study.

Sep 03, 2020

Up to 15% of patients with major depressive disorder (MDD) attempt suicide and up to 2% complete suicide. This was a post-hoc analysis aimed to evaluate the risk of suicide ideation and behavior assoc...

Prediction of clinical and biomarker conformed Alzheimer's disease and mild cognitive impairment from multi-feature brain structural MRI using age-correction from a large independent lifespan sample.

Sep 03, 2020

Structural neuroimaging has been applied to the identification of individuals with Alzheimer's disease (AD) and mild cognitive impairment (MCI). However, these methods are greatly impacted by age limi...

Thienorphine induces antinociception without dependence through activation of κ- and δ-, and partial activation of μ- opioid receptor.

Sep 03, 2020

Thienorphine hydrochloride is a new anti-relapse drug for opioid abusers that is currently in phase II clinical trial. In the present study, the antinociception, dependence, and signal transduction in...

Review of addiction risk potential associated with adolescent opioid use.

Sep 03, 2020

Adolescence is a critical period of development with robust behavioral, morphological, hormonal, and neurochemical changes including changes in brain regions implicated in the reinforcing effects of d...

Postoperative Opioid Utilization Associated with Revision Risk Following Primary Shoulder Arthroplasty.

Sep 03, 2020

With a substantial increase in utilization of primary shoulder arthroplasty, it is important to understand risk factors that may signal early failure and need for revision. Recent studies have reporte...

Genomic signatures of honey bee association in an acetic acid symbiont.

Sep 03, 2020

Recent declines in the health of the honey bee have startled researchers and lay people alike as honey bees are agriculture's most important pollinator. Honey bees are important pollinators of many ma...

An intracochlear DP-gram: Proof of principle in noise-damaged rabbits.

Sep 03, 2020

Distortion-product otoacoustic emissions (DPOAEs) can be used to assess cochlear damage and are often evaluated by generating a DP-gram in which 2f-f DPOAE levels are plotted as a function of the high...

Functional and radiological outcome of anterior retroperitoneal versus posterior transforaminal interbody fusion in the management of single-level lumbar degenerative disease.

Sep 03, 2020

In this study the authors compared the anterior lumbar interbody fusion (ALIF) and posterior transforaminal lumbar interbody fusion (TLIF) techniques in a homogeneous group of patients affected by sin...

An Operational Clinical Approach in the Diagnosis and Management of Sleep Bruxism: A First Step Towards Validation.

Sep 03, 2020

Exacerbation of nighttime sleep-related oromotor activity is often recognized as a relevant clinical entity commonly known as sleep bruxism (SB). Many pragmatic issues about SB diagnosis and managemen...

Smoking Behaviors in Psychotic Patients and Quality of Life

Aug 31, 2020

The prevalence of smoking in patients with psychosis is high, which can be explained due to the symptom-relieving effects of smoking. The objective of this study is to evaluate smoking behavior in pat...

Medicinal Cannabinoids for Treating Mental Disorders

Aug 31, 2020

Medical cannabinoids have been legalized in several parts across the globe due to the presence of tetrahydrocannabinol (THC) and cannabidiol (CBD), compounds that are known to have therapeutic effects...

Association between First Abortion and First Non-Fatal Suicide Attempt

Aug 31, 2020

Several studies have derived an association between abortion and mental health issues. However, most of the research conducted on abortion and mental health had low accuracy and participation rates. T...

Maternal Cytokine Concentrations and Risk of Psychosis in Offspring

Aug 31, 2020

Cytokines are a category of small proteins that play an important role in cell signaling. Recent studies have suggested that higher concentrations of cytokines in pregnant mothers can increase the ris...

Psychiatric Symptoms Caused by Cannabis Constituents

Aug 31, 2020

Cannabis is one of the most widely used drug worldwide, and it has also been legalized in several states in the US, Canada, and other countries around the world. The increased consumption of cannabis ...

Effectiveness of Zinc Supplementation on Lithium-Induced Alterations in Thyroid Functions.

Aug 31, 2020

Lithium is an integral drug used in the management of acute mania, unipolar and bipolar depression, and prophylaxis of bipolar disorders. Thyroid abnormalities have been associated with treatment with...

Early intervention for people at high risk of developing bipolar disorder: a systematic review of clinical trials.

Aug 31, 2020

Early intervention approaches are built on the premise of preventing disability, burden, and cognitive sequelae caused by bipolar disorder. The objective of this systematic review was to characterise ...

A Systematic Review and Meta-Analysis of Randomized Sham-Controlled Trials of Repetitive Transcranial Magnetic Stimulation for Bipolar Disorder.

Aug 31, 2020

Repetitive transcranial magnetic stimulation (rTMS) is effective in treating unipolar depression. However, the efficacy of rTMS in bipolar disorder (BD) is unclear. This meta-analysis aimed to examine...

The effectiveness of aromatherapy on preoperative anxiety in adults: A systematic review and meta-analysis of randomized controlled trials.

Aug 31, 2020

Preoperative anxiety is very common in adults awaiting all types of surgical procedures, which can interfere with the start and completion of surgery and increase the risk of postoperative complicatio...

Association between psychological morbidities and information provision, reliability, and satisfaction among disaster victims: A cross-sectional study.

Aug 31, 2020

Providing information about disaster relief services and recovery processes reduces the damage from disasters and enables disaster victims to respond to disasters effectively. The present study aimed ...

Esketamine Nasal Spray for Rapid Reduction of Depressive Symptoms in Patients with Major Depressive Disorder Who Have Active Suicide Ideation with Intent: Results of a Phase 3, Double-Blind, Randomized Study (ASPIRE II).

Aug 31, 2020

Patients with major depressive disorder (MDD) having active suicidal ideation with intent require immediate treatment.This double-blind study (ASPIRE II) randomized adults (aged 18-64 years) with MDD ...

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