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Psychiatry General

Promoting research engagement among women with addiction: Impact of recovery peer support in a pilot randomized mixed-methods study.

May 22, 2023

The impact of involving peers on research engagement is largely unknown. The purpose of this pilot study, a part of a larger research, was to evaluate the impact of recovery peer involvement as a stud...

Dapagliflozin inhibits the activity of lateral habenula to alleviate diabetes mellitus-induced depressive-like behavior.

May 22, 2023

The prevalence of depression in diabetes mellitus (DM) patients is very high, and it severely impacts the prognosis and quality of life of these patients. Sodium-glucose co-transporter 2 (SGLT2) inhib...

Factors associated with objective and subjective cognitive impairment in Chinese patients with acute major depressive disorder.

May 22, 2023

Patients diagnosed withmajor depressive disorder (MDD) usually experience impaired cognitive functioning, which might negatively impact their clinical and functional outcomes. This study aimed to inve...

The role of NMDA receptors in bipolar disorder: A systematic review.

May 22, 2023

Glutamatergic transmission and N-methyl-D-aspartate receptors (NMDARs) have been implicated in the pathophysiology schizophrenic spectrum and major depressive disorders. Less is known about the role o...

The Chronic Pharmacological Antagonism of the CB Receptor is not Involved in the Behavioral Effects of Antidepressants Administered in Mice Submitted to Chronic Unpredictable Stress.

May 22, 2023

Several pieces of evidence suggest that the monoaminergic theory of depression cannot fully explain all behavioral and neuroplastic changes observed after antidepressant chronic treatment. Other molec...

Long-lasting restoration of memory function and hippocampal synaptic plasticity by focused ultrasound in Alzheimer's disease.

May 22, 2023

Focused ultrasound (FUS) is a medical technology that non-invasively stimulates the brain and has been applied in thermal ablation, blood-brain barrier (BBB) opening, and neuromodulation. In recent ye...

Airborne pollen grain detection from partially labelled data utilising semi-supervised learning.

May 22, 2023

Airborne pollen monitoring has been conducted for more than a century now, as knowledge of the quantity and periodicity of airborne pollen has diverse use cases, like reconstructing historic climates ...

Occurrence of Depression and Anxiety Resulting From Long-Term Exposure to Multiple Ambient Air Pollutants

May 16, 2023

The following is a summary of "Long-term Exposure to Multiple Ambient Air Pollutants and Incident Depression and Anxiety," published in the February 2023 issue of Psychiatry by Yang et al. For ...

Brain Binding of Serotonin 4 Receptor in MDD and Its Association with Memory Impairment

May 15, 2023

The following is a summary of "Serotonin 4 Receptor Brain Binding in Major Depressive Disorder and Association With Memory Dysfunction," published in the February 2023 issue of Psychiatry by Köhler-F...

Neuroendocrine response to a psychosocial stress test is not related to schizotypy but cortisol elevation predicts inflexibility of semantic memory retrieval.

May 15, 2023

An altered stress response can contribute to the transition from preclinical psychotic symptoms to the clinical manifestation of schizophrenia and other psychotic disorders. The present study was aime...

The Association between Peripheral Inflammation, Brain Glutamate and Antipsychotic Response in Schizophrenia: data from the STRATA collaboration.

May 15, 2023

Glutamate and increased inflammation have been separately implicated in the pathophysiology of schizophrenia and the extent of clinical response to antipsychotic treatment. Despite the mechanistic lin...

Rhynchophylline inhibits methamphetamine dependence via modulating the miR-181a-5p/GABRA1 axis.

May 15, 2023

Uncaria rhynchophylla (Miq.) Miq. ex Havil. is a plant species that is routinely devoted in traditional Chinese medicine to treat central nervous system disorders. Rhynchophylline (Rhy), a predominant...

Effects of the DICE Method to Improve Timely Recognition and Treatment of Neuropsychiatric Symptoms in Early Alzheimer's Disease at the Memory Clinic: The BEAT-IT Study.

May 15, 2023

Neuropsychiatric symptoms (NPS) are highly prevalent in Alzheimer's disease (AD) and are associated with negative outcomes. However, NPS are currently underrecognized at the memory clinic and non-phar...

Olfactory Obsessions: A Study of Prevalence and Phenomenology in the Course of Obsessive-Compulsive Disorder.

May 15, 2023

Olfactory obsessions (OOs) are rarely described in the medical literature. The features of OOs appear consistent with characteristics of a typical obsession, but since they do not involve the realm of...

Genetic examination of the Mood Disorder Questionnaire and its relationship with bipolar disorder.

May 15, 2023

The Mood Disorder Questionnaire (MDQ) is a common screening tool for bipolar disorder that assesses manic symptoms. Its utility for genetic studies of mania or bipolar traits has not been fully examin...

Impact of atypical working hours on sleep and mood among healthcare workers.

May 15, 2023

Atypical working hours have raised serious concerns about health effects, such as sleep disorders and psychological repercussions. These schedules are frequent among health professionals having the ob...

Generation and Characterization of the First Murine Model of Alzheimer's Disease with Mutated AβPP Inserted in a BALB/c Background (C.B6/J-APPswe).

May 15, 2023

Numerous mouse models of Alzheimer's disease (AD) are available, but all suffer from certain limitations, thus prompting further attempts. To date, no one model exists with amyloidopathy in a BALB/c s...

Cannabidiol in children with treatment-resistant epilepsy with myoclonic-atonic seizures.

May 15, 2023

This multicenter study aimed to evaluate the efficacy and tolerability of add-on cannabidiol (CBD) in treatment-resistant patients with epilepsy with myoclonic-atonic seizures (EMAtS) (n = 22) and S...

The Relationship Between Cannabis Use and Affect Differs by Social Context

May 12, 2023

The following is a summary of "Association between affect and cannabis use varies by social context," published in the February 2023 issue of Drug and Alcohol Dependence by Denson et al. The gl...

The Evolution of Beliefs and Attitudes Towards Alcohol Consumption Across Generations

May 11, 2023

The following is a summary of "Generational shifts in attitudes and beliefs about alcohol: An age-period-cohort approach," published in the February 2023 issue of Drug and Alcohol Dependence by Living...

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