Sep 17, 2020

We utilized a national administrative database to investigate drivers of immediate adverse economic and hospital outcomes, including non-routine discharge, prolonged length of stay (LOS), and admissio...

Sep 17, 2020

A continuing complication, pressure injuries are due to sustained mechanical loading and tissue deformations, which can then be exacerbated by additional intrinsic and extrinsic risk factors. Although...

Sep 17, 2020

Two prior population-based (children born in Olmsted County, MN), retrospective cohort studies both found that multiple exposures to anesthesia before age 3 were associated with a significant increase...

Sep 17, 2020

The decline of nutritional status and depressive symptoms are pandemic in heart failure patients and functional status may play a pivotal role between these. This study aimed to determine whether nutr...

Sep 17, 2020

Coronary tortuosity (CT) is commonly encountered in postmenopausal females and is usually present without obstructive lesions. Circulating sclerostin levels are elevated in postmenopausal females. In ...

Sep 14, 2020

Sleep spindles, defining oscillations of stage 2 non-rapid eye movement sleep (N2), mediate memory consolidation. Schizophrenia is characterized by reduced spindle activity that correlates with impair...

Sep 14, 2020

Reports of psychiatric morbidity associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection tend to be limited by geography and patients' clinical status. Representative sa...

Sep 14, 2020

Lithium is an effective prophylactic and anti-manic treatment in bipolar disorder; however, its use is declining through perceived poor tolerance and toxicity. Lithium inhibits inositol monophosphatas...

Sep 14, 2020

Depressive and neurocognitive disorders are debilitating conditions that account for the leading causes of years lived with disability worldwide. However, there are no biomarkers that are objective or...

Sep 14, 2020

Altered synaptic plasticity is often associated with major depressive disorder (MDD). Disease-associated changes in synaptic functions are tightly correlated with altered microRNA (miRNA) expression. ...

Sep 14, 2020

Rapidly accumulating data from mobile assessments are facilitating our ability to track the patterns of emotions, behaviors, biologic rhythms, and their contextual influences in real time. These appro...

Sep 14, 2020

Individuals with severe psychiatric disorders have a reduced life expectancy compared to the general population. At the biological level, patients with these disorders present features that suggest th...

Sep 14, 2020

Opioid overdose prevention education and naloxone distribution (OEND) programs include information on general risk factors, overdose recognition, and naloxone utilization. This study evaluated a perso...

Sep 14, 2020

Veterans experience chronic pain at greater rates than the rest of society and are more likely to receive long-term opioid therapy (LTOT), which, at high doses, is theorized to induce maladaptive neur...

Sep 14, 2020

Atherosclerosis is mainly caused by stress in arterial microenvironments, which results in the formation of stress granules as a consequence of the stress response. As the core protein of stress granu...

Sep 14, 2020

To identify a parsimonious set of markers that optimally predicts subsequent clinical progression from normal to mild cognitive impairment (MCI).250 clinically normal adults (mean age = 73.6 years,...

Sep 14, 2020

The detection and diagnosis of Parkinson's disease (PD) is of paramount importance for optimal treatment and for participation in disease-modifying trials. The present study assesses the diagnostic ac...

Sep 14, 2020

Bodily gestures play an important role in the communication of expressive intentions between humans. Music ensemble performance, as an outstanding example of nonverbal human communication, offers an e...

Sep 14, 2020

Although fears of negative and positive social evaluation are hallmark cognitive features of social anxiety, attentional difficulties may exacerbate the relation between fears of social evaluation and...

Sep 14, 2020

The use of controlled substances like cocaine increases the risk of cardiovascular disease (CVD) and myocardial infarction (MI). However, outside of alcohol and tobacco, substance use is not included ...