Jun 12, 2023

Gerstmann-Sträussler-Scheinker (GSS) is a rare prion disease with heterogeneous clinical presentation. Although sleep-related abnormalities are prominent and well-known in other prion diseases such a...

Jun 12, 2023

Treatment of schizophrenia remains a major challenge. Recent studies have focused on glutamatergic signaling hypoactivity through N-methyl-D-aspartate (NMDA) receptors. Low-intensity pulsed ultrasound...

Jun 12, 2023

Epigenetic aberrations are suggested to play an important role in transcriptional alterations in Alzheimer's disease (AD). One of the key mechanisms of epigenetic regulation of gene expression is thro...

Jun 12, 2023

Alzheimer's disease (AD) is diagnosed by the presence of both amyloid β and tau proteins. Recent advances in molecular PET imaging have made it possible to assess the accumulation of these proteins i...

Jun 12, 2023

Chronic mania is a mental health disorder that has been described by various psychiatrists in the past but currently is not a part of nosology. Robust epidemiological data for chronic mania are lackin...

Jun 12, 2023

People with diagnoses of intellectual disability or serious mental illness have higher mortality rates due to physical comorbidities; better understanding is needed to guide best practice in provision...

Jun 12, 2023

Development and functioning of attention-a key component of human cognition-can be affected by environmental factors. We investigated whether long- and short-term exposure to particulate matter with a...

Jun 05, 2023

Transgender persons can use gender-affirming hormone therapy (GAHT) to align their physical appearance with their identified gender. Many transgender persons report poor sleep, but the effects of GAHT...

Jun 05, 2023

Studies have shown that community-based group rehabilitation activities can have a positive impact on patients.This study attempted to improve schizophrenia patients' social and self-cognition through...

Jun 05, 2023

The hypothesis of dopamine dysfunction in psychosis has evolved since the mid-twentieth century. However, clinical support from biochemical analysis of the transmitter in patients is still missing. Th...

Jun 05, 2023

This issue of the Biomedical Journal contains a special section about cell senescence. The reader gets an insight into the crosstalk between immune system and senescent cells, into an approach to figh...

Jun 05, 2023

Manic and depressive mood states in bipolar disorder (BD) may emerge from the non-linear relations between constantly changing mood symptoms exhibited as a complex dynamic system. Dynamic Time Warp (D...

Jun 05, 2023

Common genetic variants located in calcium channel genes are important markers of genetic susceptibility for bipolar disorder (BD). Previous clinical trials with Calcium Channel Blocker (CCB) medicati...

May 29, 2023

Combination therapy with antipsychotics has been investigated for treating schizophrenia, and has shown clear advantages among non-invasive therapies. Transcutaneous electrical acupoint stimulation (T...

May 29, 2023

To examine the impact of comorbid psychiatric disorders on postoperative outcomes in pulmonary lobectomy patients.A retrospective analysis of the Healthcare Cost and Utilization Project Nationwide Rea...

May 29, 2023

The efficacy and safety of lurasidone monotherapy in patients with bipolar I depression with or without rapid cycling has not been previously investigated.We performed subgroup analysis (rapid cycling...

May 22, 2023

Ulotaront (SEP-363856) is a novel agonist at trace amine-associated receptor 1 and serotonin 5-HT receptors in clinical development for the treatment of schizophrenia. Previous studies demonstrated ul...

May 22, 2023

Narcolepsy type 1 (NT1) is a neurological disorder caused by disruption of hypocretin (HCRT; or orexin) neurotransmission leading to fragmented sleep/wake states, excessive daytime sleepiness (EDS), a...

May 22, 2023

Cerebral blood flow (CBF) plays a critical role in the maintenance of neuronal integrity, and CBF alterations have been linked to deleterious white matter changes. Several studies report CBF and white...

May 22, 2023

Individuals with severe mental illness are at a higher risk of violence than the general population. However, there is a lack of available and simple tools to screen for the risk of violent offending ...