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Psychiatry General

What is the “best intro”—explanatory versus pragmatic antipsychotic drug trials

Oct 26, 2020

There have been many studies that have been conducted so far in order to measure the BeST InTro study which has been conducted by famous scientists like Erik Johnsen and his allies. There was an effor...

The effect of flexible assertive community treatment in Denmark: a quasi-experimental controlled study

Oct 26, 2020

There have been various studies that are being conducted so far in order to measure the flexible assertive community treatment which is a community-based model to cure patients who have been suffering...

Immersive virtual reality vs. non-immersive distraction for pain management of children during bone pins and sutures removal: A randomized clinical trial protocol.

Oct 26, 2020

To examine the efficacy of an immersive virtual reality distraction compared with an active non-immersive distraction, such as video games on a tablet, for pain and anxiety management and memory of pa...

Low-dose ketamine for acute pain control in the emergency department: A systematic review and meta-analysis.

Oct 26, 2020

There has been increased interest in the use of low dose ketamine (LDK) as an alternative analgesic for the management of acute pain in the emergency department (ED). The objective of this systematic ...

Structural and functional alterations in untreated patients with major depressive disorder and bipolar disorder experiencing first depressive episode: A magnetic resonance imaging study combined with follow-up.

Oct 26, 2020

Magnetic resonance imaging (MRI) could assist in identifying objective biomarkers and follow-up study could effectively improve subjective diagnostic accuracy. By combining MRI with follow-up, this st...

Chronic Valproic Acid Administration Increases Plasma, Liver, and Brain Ammonia Concentration and Suppresses Glutamine Synthetase Activity.

Oct 26, 2020

Asymptomatic valproic acid (VPA)-induced hyperammonemia in the absence of liver impairment is fairly common. However, the underlying mechanisms through which VPA causes elevation in plasma ammonia (NH...

Eating disorder pathology and compulsive exercise during the COVID-19 public health emergency: Examining risk associated with COVID-19 anxiety and intolerance of uncertainty.

Oct 26, 2020

COVID-19 has led to disruptions in daily living and increased uncertainty about physical, financial, social, and psychological consequences, which may contribute to anxiety, eating disorder (ED) patho...

Computational modelling of attentional bias towards threat in pediatric anxiety.

Oct 26, 2020

Computational modelling can be used to precisely characterise the cognitive processes involved in attentional biases towards threat, yet so far has only been applied in the context of adult anxiety. F...

Development of a brief psychological intervention for perinatal depression (BIND-P).

Oct 26, 2020

Lack of recognition in national programs, poor referral system, and non-availability of trained human resources are the important barriers for the delivery of perinatal depression (PND) services in lo...

Exparel for Postoperative Pain Management: a Comprehensive Review.

Oct 26, 2020

Multimodal pain management is the most effective way to treat postsurgical pain. However, the use of opioids for acute pain management has unfortunately been a significant contributor to the current...

The role of withdrawal in mesocorticolimbic drug cue reactivity in opioid use disorder.

Oct 26, 2020

Opioid use disorder (OUD) is characterized by heightened cognitive, physiological, and neural responses to opioid-related cues that are mediated by mesocorticolimbic brain pathways. Craving and withdr...

Direct Peripheral Nerve Stimulation for the Treatment of Complex Regional Pain Syndrome: A 30-Year Review.

Oct 26, 2020

Complex regional pain syndrome (CRPS), formerly known as reflex sympathetic dystrophy (RSD), is a difficult to treat condition characterized by debilitating pain and limitations in functional ability....

The Role of the Subthalamic Nucleus in Sequential Working Memory in De Novo Parkinson's Disease.

Oct 26, 2020

Deficits in maintaining and manipulating sequential information online can occur even in patients with mild Parkinson's disease. The subthalamic nucleus may play a modulatory role in the neural system...

Biological fluid levels of iron and iron-related proteins in parkinson's disease: Review and meta-analysis.

Oct 26, 2020

The present systematic review and meta-analysis try to establish the cerebrospinal fluid (CSF) and serum/plasma levels of iron and iron-related proteins (ferritin, transferrin, lactoferrin, haptoglobi...

Association between postnatal second-hand smoke exposure and ADHD in children: a systematic review and meta-analysis.

Oct 26, 2020

Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder which is caused by the interplay of genetic and environmental risk factors such as second-hand smoke (SHS). The associa...

Detecting subtle mobility changes among older adults: the Quantitative Timed Up and Go test.

Oct 26, 2020

The Quantitative Timed Up and Go (QTUG) test uses wearable sensors, containing a triaxial accelerometer and an add-on triaxial gyroscope, to quantify performance during the TUG test with potential to ...

Perceived burdensomeness is a curvilinear, short-term predictor of suicide ideation in a community sample of adults.

Oct 26, 2020

Our primary aim was to test the Interpersonal Theory of Suicide's synergy hypothesis (i.e., the interaction between perceived burdensomeness and thwarted belongingness) in the proximal prediction of s...

Neuroprotective effects of flavone luteolin in neuroinflammation and neurotrauma.

Oct 26, 2020

Neuroinflammation leads to neurodegeneration, cognitive defects, and neurodegenerative disorders. Neurotrauma/traumatic brain injury (TBI) can cause activation of glial cells, neurons, and neuroimmune...

Alterations in Plasma Kynurenine Pathway Metabolites in Children and Adolescents with Bipolar Disorder and Unaffected Offspring of Bipolar Parents: A preliminary study.

Oct 26, 2020

There has been growing scientific evidence in recent years that bipolar disorder (BD) is associated with alterations in the kynurenine (KYN) pathway. However, many of these studies have been limited b...

Evaluation of long-acting injectable antipsychotics with the corresponding oral formulation in a cohort of patients with schizophrenia: a real-world study in Spain.

Oct 22, 2020

To date, only a few studies compared some long-acting injectables (LAIs) antipsychotics showing similar symptom improvement, relapse rates and adherence to treatment. We evaluated the use of LAIs anti...

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