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Psychiatry General

Effect of the morphine/heroin vaccine on opioid and non-opioid drug-induced antinociception in mice.

Nov 12, 2020

Pain is a common symptom in patients with opioid use disorder (OUD), which increases synthetic and illicit synthetic opioid abuse and even fatalities due to opioid overdose. Many FDA-approved drugs ar...

Pathological findings in a patient with alpha-synuclein p.A53T and familial Parkinson's disease.

Nov 12, 2020

The present report documents a patient harboring an alpha-synuclein p.A53T variant from a family presenting with autosomal dominant inheritance, including four patients clinically diagnosed with Parki...

Cost-effectiveness of duloxetine for knee OA subjects: The role of pain severity.

Nov 12, 2020

Establish the impact of pain severity on the cost-effectiveness of generic duloxetine for knee osteoarthritis (OA) in the United States.We used a validated computer simulation of knee OA to compare us...

Predictors of Bipolar Disorder Versus Schizophrenia Diagnosis in a Multicenter First Psychotic Episode Cohort: Baseline Characterization and a 12-Month Follow-Up Analysis.

Nov 09, 2020

The aim of this study was to identify predisposing factors and clinical features at baseline that might help predict diagnosis of bipolar disorder vs schizophrenia in a first-episode psychosis (FEP) c...

Preliminary evidence for a relationship between prospective memory and PTSD symptoms in the general population.

Nov 09, 2020

PTSD sufferers often have problems with remembering the past, but do they also have trouble remembering tasks to be completed in the future? We argue characteristics of PTSD-such as negative appraisal...

Post-COVID-19 Epidemic: Allostatic Load among Medical and Nonmedical Workers in China.

Nov 09, 2020

As the fight against the COVID-19 epidemic continues, medical workers may have allostatic load.During the reopening of society, medical and nonmedical workers were compared in terms of allostatic load...

Action mechanism of Roman chamomile in the treatment of anxiety disorder based on network pharmacology.

Nov 09, 2020

Anxiety disorder is a common psychiatric disease. Roman chamomile as medicine or tea has long been used as a mild tranquilizer to reduce anxiety, but the mechanism is unclear. This research is based o...

Adapting implementation science for higher education research: the systematic study of implementing evidence-based practices in college classrooms.

Nov 09, 2020

Finding better ways to implement effective teaching and learning strategies in higher education is urgently needed to help address student outcomes such as retention rates, graduation rates, and learn...

Muscarinic receptor signaling in the amygdala is required for conditioned taste aversion.

Nov 09, 2020

The sense of taste provides information regarding the nutrient content, safety or potential toxicity of an edible. This is accomplished via a combination of innate and learned taste preferences. In co...

Attention-deficit/ hyperactivity disorder symptoms and suicidal ideation among college students: A structural equation modeling approach.

Nov 09, 2020

Suicidal ideation (SI) among college students is frequently reported. However, the mediating roles of depressive and anxiety symptoms between attention-deficit/hyperactivity disorder (ADHD) symptoms a...

Post-operative Opioid Prescribing and Consumption after Hysterectomy: a Prospective Cohort Study.

Nov 09, 2020

To examine opioid prescribing and consumption patterns after hysterectomy and identify factors associated with post-operative opioid consumption.Prospective cohort study.Single university medical cent...

Health economic design for cost, cost-effectiveness and simulation analyses in the HEALing Communities Study.

Nov 09, 2020

The HEALing Communities Study (HCS) is designed to implement and evaluate the Communities That HEAL (CTH) intervention, a conceptually driven framework to assist communities in selecting and adopting ...

Health communication campaigns to drive demand for evidence-based practices and reduce stigma in the HEALing communities study.

Nov 09, 2020

The HEALing Communities Study (HCS) is testing whether the Communities that Heal (CTH) intervention can decrease opioid overdose deaths through the implementation of evidence-based practices (EBPs) in...

Resurrecting the discussion on neurotoxicity of lithium at therapeutic levels.

Nov 05, 2020

Lithium is widely used in the treatment of bipolar disorder. Here we describe the syndrome of irreversible lithium-effectuated neurotoxicity in a patient within therapeutic doses and levels, which per...

Clinical correlates of seasonality in bipolar disorder: A specifier that needs specification?

Nov 05, 2020

Seasonal pattern (SP) is a bipolar disorder (BD) specifier that indicates a tendency towards affective relapses during specific moments of the year. SP affects 15-25% of BD patients. In the past, SP w...

Population Pharmacokinetics of Cariprazine and its Major Metabolites.

Nov 05, 2020

Cariprazine, a dopamine D-preferring D/D receptor partial agonist, is approved for the treatment of adults with schizophrenia (1.5-6 mg/day) and manic/mixed (3-6 mg/day) episodes associated with bip...

Examining quality of life in an Australian cohort of people with epilepsy over six years - Understanding the role of stigma and mood.

Nov 05, 2020

Research examining quality of life (QoL) among people living with epilepsy (PWE) consistently highlights the detrimental impact of stigma, anxiety, and depression, as well as the dynamic and changing ...

New approach to patients with premature ejaculation: Do social cognition and attachment profiles play a role in premature ejaculation?

Nov 05, 2020

Premature ejaculation is the most prevalent male sexual dysfunction and causes significant individual and relational distress in subjects. This study aimed to investigate the underlying psychopatholog...

Impaired hypothalamic feedback dysregulates brain glucocorticoid signaling in genetically-selected Marchigian Sardinian alcohol-preferring rats.

Nov 05, 2020

Genetically-selected Marchigian Sardinian alcohol-preferring (msP) rats display comorbid symptoms of increased alcohol preference and elevated anxiety-like behavior. Heightened stress sensitivity in m...

Spatiotemporal Trends in Discarded Needle Reports in San Francisco Over a 10-year Period, 2010-2019.

Nov 05, 2020

To describe the geographic and spatiotemporal distribution of needle reports in San Francisco, and examine spatial relationships between needle reports and needle disposal boxes, needle disposal kiosk...

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