Nov 16, 2020

Anxiety is a common symptom in young individuals with autism spectrum disorder (ASD). Though psychological therapies for treating anxiety have been proposed, their efficacy has not been established. T...

Nov 16, 2020

With the opioid crisis continually increasing, it is crucial to understand the biological and biochemical mechanisms of opioid abuse. This study aims to identify the genetic risk variants for opioid u...

Nov 16, 2020

Various therapies have been recognized as adjuncts to pharmacotherapy for bipolar disorder patients. However, their efficacy has not been well studied. This study aims to evaluate how using manualized...

Nov 16, 2020

Several observational studies have highlighted the associations between C-reactive protein and interleukin, a cytokine-stimulating substance that induces depressive symptoms. However, whether inflamma...

Nov 12, 2020

In this work, we studied a series of carfentanyl amide-based opioid derivatives targeting the mu opioid receptor (μOR) and the delta opioid receptor (δOR) heteromer as a credible novel target in pai...

Nov 12, 2020

The purpose of this study is to investigate the association between online sexual solicitation (OSS) and internet accessibility, usage, and addiction in adolescents. The study was conducted with 48 ad...

Nov 12, 2020

During the first 6-months of the COVID-19 pandemic, the primary weapons against the spread of the virus have included local government orders for restriction of movement and broad implementation of fa...

Nov 12, 2020

Dysfunction of cholinergic system plays an important role in disease associated with cognitive blockage, such as Alzheimer's disease (AD). Central administration of scopolamine, an antagonist of acety...

Nov 12, 2020

Parkinson's disease (PD) is diagnosed when motor symptoms emerges, which almost 70% of dopamine neurons are lost. Therefore, early diagnosis of PD is crucial to prevent the progress of disease. Blood-...

Nov 12, 2020

Neurocognitive dysfunction is a common feature of bipolar disorder even in euthymia, and psychopharmacological treatment could have an effect on cognition. Long-term prescription of benzodiazepines in...

Nov 12, 2020

Resistance to pharmacological agents is commonly encountered in the treatment of acute episodes of mania. In contemporary practice guidelines, electroconvulsive therapy (ECT), once a widely used stand...

Nov 12, 2020

A narrative review of past, present, and future of lithium use in psychiatry.The most important references on the topic were reviewed with special emphasis on the author's works.The history of medical...

Nov 12, 2020

Anxiety disorders are highly prevalent across the lifespan, although diagnoses peak early in adolescence. As a method for inhibiting fear, safety signals have the potential to augment conventional tre...

Nov 12, 2020

To examine sexual health, including sexual satisfaction, and perceived changes in relationships and sexual relationships of human papillomavirus oropharyngeal cancer (HPV-OPC) survivors ≥12 months f...

Nov 12, 2020

The lungs are major sites of metastases for several cancer types, including breast cancer (BC). Prognosis and quality of life of BC patients that develop pulmonary metastases are negatively impacted. ...

Nov 12, 2020

Attention deficit hyperactivity disorder (ADHD) is a disorder characterized by problems of inattention and impulsive hyperactivity. Equine-assisted activities and therapies (EAAT) have become an emerg...

Nov 12, 2020

Mortality of Alcohol-related-Liver-Disease (ArLD) is increasing, and liver fibrosis stage is the best mortality predictor. Non-invasive-tests (NIT) are increasingly used to detect fibrosis, but their ...

Nov 12, 2020

Humans are highly social creatures who use others' movements to evaluate their social competencies. Smooth movement specifically signals an attractive, trustworthy or competent person. Those with Deve...

Nov 12, 2020

Fibromyalgia is characterized by the amplification of central nervous system pain with concomitant fatigue, sleep, mood disorders, depression, and anxiety. It needs extensive pharmacological therapy. ...

Nov 12, 2020

Palliative care in patients with advanced heart failure is strongly recommended by Clinical Practice Guidelines. We aimed to calculate the prevalence of advanced heart failure in admitted patients, to...