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Psychiatry General

Comparing an All-RN Unit to a Mixed-Skill Unit at a Hospital.

Nov 16, 2020

The aim of this study was to assess the differences in patient complications as well as patient and staff satisfaction between a mixed-skill unit and an all-registered nurse (RN) unit.It is recognized...

Greater Socioeconomic Disadvantage is Associated with Worse Symptom Severity at Initial Presentation in Patients Seeking Care for Lumbar Disc Herniation.

Nov 16, 2020

Retrospective, observational study.To determine the association of patient socioeconomic disadvantage, insurance type, and other characteristics on presenting symptom severity in patients with isolate...

Influence of Depressive Symptoms on the Outcome of Lumbar Spine Fusion - a 5-year Follow-up Study.

Nov 16, 2020

Prospective follow-up study.The aim of this study was to assess if depressive symptoms change the outcome of lumbar spine fusion (LSF) surgery at a 5-year follow-up.Previous reports of the influence o...

High-dimensional brain-wide functional connectivity mapping in magnetoencephalography.

Nov 16, 2020

Brain functional connectivity (FC) analyses based on magneto/electroencephalography (M/EEG) signals have yet to exploit the intrinsic high-dimensional information. Typically, these analyses are constr...

Ursodeoxycholic acid protects dopaminergic neurons from oxidative stress via regulating mitochondrial function, autophagy, and apoptosis in MPTP/MPP-induced Parkinson's disease.

Nov 16, 2020

Neuroprotection targeting mitochondrial dysfunction has been proposed as a potential therapeutic strategy for Parkinson's disease (PD). Ursodeoxycholic acid (UDCA) has been shown to prevent neuronal d...

Emerging potential of cannabidiol in reversing proteinopathies.

Nov 16, 2020

The aberrant accumulation of disease-specific protein aggregates accompanying cognitive decline is a pathological hallmark of age-associated neurological disorders, also termed as proteinopathies, inc...

Mood stabilizers and/or antipsychotics for bipolar disorder in the maintenance phase: a systematic review and network meta-analysis of randomized controlled trials.

Nov 16, 2020

We searched Embase, PubMed, and CENTRAL from inception until 22 May 2020 to investigate which antipsychotics and/or mood stabilizers are better for patients with bipolar disorder in the maintenance ph...

Effects of Lithium Combined with Second-Generation Antipsychotics for the Treatment of Manic Episodes in Patients with Bipolar Disorder: A Naturalistic Study in China.

Nov 16, 2020

To explore the therapeutic effects of lithium combined with second-generation antipsychotics (SGAs) of quetiapine, clozapine, olanzapine, and risperidone for the treatment of manic episodes in patient...

The time course of psychotic symptom side effects of ketamine in the treatment of depressive disorders: a systematic review and meta-analysis.

Nov 16, 2020

Ketamine is a potential rapid-acting treatment for depression. Studies have suggested that the side effects are minimal and temporary, but the psychotic symptom side effects have yet to be fully exami...

The impact of substance use disorder on the mental health among COVID-19 patients: A protocol for systematic review and meta-analysis.

Nov 16, 2020

Substance use disorder (SUD) is associated with a high risk of physical and mental illness such as anxiety, depression, personality disorders, eating disorders, and abnormal mood changes. During the p...

Incorporating a Trauma-Informed Care Protocol Into Pediatric Trauma Evaluation: The Pediatric PAUSE Does Not Delay Imaging or Disposition.

Nov 16, 2020

Trauma evaluation in the emergency department (ED) can be a stressful event for children. With the goal of minimizing pain, anxiety, and unneeded interventions in stable patients, we implemented the P...

Nucleosome clutches are regulated by chromatin internal parameters.

Nov 16, 2020

Nucleosomes cluster together when chromatin folds in the cell to form heterogeneous groups termed "clutches". These structural units add another level of chromatin regulation, for example during cell ...

Does background metformin therapy influence the cardiovascular outcomes with SGLT-2 inhibitors in type 2 diabetes?

Nov 16, 2020

Metformin has been recommended as a first-line antidiabetic drug (ADD) for all patients with type 2 diabetes even in the presence of high cardiovascular (CV) risk by American Diabetes Association. In ...

Death and Grieving for Family Caregivers of Loved Ones With Life-Limiting Illnesses in the Era of COVID-19: Considerations for Case Managers.

Nov 16, 2020

Family caregivers of a loved one with a life-limiting or terminal illness are often overwhelmed by, and underprepared for, their responsibilities. They often need help from family members and friends ...

Efficacy and safety of Hominis placenta pharmacopuncture on mild cognitive impairment: Randomized, double blind, placebo-controlled, multi-center trial.

Nov 16, 2020

Mild cognitive impairment (MCI) is cognitive decline which can be observed in a wide range of cognitive domains. It is considered as a prodromal stage of dementia; therefore, strategies for treatment ...

Toxicology Screening Testing in Patients Undergoing Spine Surgery: A Prospective Observational Pilot Study.

Nov 16, 2020

Chronic opioid use and polypharmacy are commonly seen in chronic pain patients presenting for spine procedures. Substance abuse and misuse have also been reported in this patient population. Negative ...

Impact of surgical technique and analgesia on clinical outcomes after lung transplantation: A STROBE-compliant cohort study.

Nov 16, 2020

There is paucity of data on the impact of surgical incision and analgesia on relevant outcomes.A retrospective STROBE-compliant cohort study was performed between July 2007 and August 2017 of patients...

Rapid Administration of Ketamine for Abscess Drainage in Children-A Dose Finding Study.

Nov 16, 2020

To estimate the minimum dose and total sedation time of rapidly infused ketamine that achieves 3 to 5 minutes of effective sedation in children undergoing abscess incision and drainage in the emergenc...

Intrinsic Brain Architecture and Attentional & Mood Symptoms

Nov 16, 2020

With the incidence of mental disorders increasing, it is essential to understand the neurodevelopmental trajectory of psychiatric symptoms. This study aims to evaluate whether the strength of cooling ...

Cortical Connectivity Antidepressant Moderators for Depressive Disorder

Nov 16, 2020

Several magnetic resonance imaging (MRI) findings suggest the role of cortical connectivity treatments in the treatment and selectivity for major depressive disorder (MDD). However, its clinical utili...

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